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Biomedical subjects

V Boucher

Publications and source records attributed to V Boucher.

4 recordsLinked to original sources

Polarization switching in a planar optical waveguide.

The multiscale expansion formalism is applied to the study of nonlinear planar optical waveguides. It allows us to describe the linear and nonlinear propagation for both transverse electric and transverse magnetic modes, and the interaction between them. An accurate computation of the nonlinear self- and cross-phase modulation coefficients allows one to give account of the polarization switching which has been observed experimentally.

Journal Article↗

Effects of speaking rate on the control of vocal fold vibration: clinical implications of active and passive aspects of devoicing.

Stevens (1991) has suggested that, while speakers control glottal apertures in producing consonants, the buildup of intraoral pressure during an oral closure creates decreases in transglottal flow, which can, in itself, reduce or halt vocal fold vibrations. The object of this study was to determine whether speakers can take advantage of such pressure effects in controlling the voicing attributes of intervocalic stops. Intraoral pressure, vocal fold vibration (Lx portions of electroglottograms), and electromyographic (EMG) activity of the orbicularis oris inferior were monitored for 6 subjects while they produced at "slow," "normal," and "fast" speaking rates utterances containing intervocalic stops /p/ and /b/. Product-moment correlations between the intervocalic pressure rises and the amplitude contour of Lx showed strong negative relationships at normal-to-fast rates of speech. However, this relationship was not maintained at slower rates, where decreases in the amplitude of Lx sometimes occurred before the onset of EMG activity in the labial adductor. The findings suggest that, at normal-to-fast rates of speech, speakers can use the passive effects of pressure in controlling vocal fold vibration for stop consonants.

Adult↗

[Desensitization].

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Desensitization, Immunologic↗

Expression of human CD4 in transgenic mice does not confer sensitivity to human immunodeficiency virus infection.

Transfection of the human CD4 molecule into mouse cells does not confer susceptibility to human immunodeficiency virus type 1 (HIV-1) infection. Expression of the human CD4 molecule in transgenic mice was seen to offer some new possibilities. However, transgenic mouse T cells expressing either the human CD4 receptor, or a hybrid human/mouse CD4 receptor alone or in conjunction with human major histocompatibility complex class I molecules, were refractory to in vitro HIV-1 infection. In addition, no infection was observed after in vivo HIV inoculation to mice of these various transgenic lines. Injection of recombinant gp160 viral protein to the transgenic mice did not alter their T and B cell populations. The existence of a dominant block in mouse cells that prevents HIV entry is discussed.

Animals↗