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Biomedical subjects

V Bishop

Publications and source records attributed to V Bishop.

30 records · Page 2Linked to original sources
PubMed1982

Single dose doxycycline, cefuroxime and pivmecillinam for treatment of bacterial cystitis.

There is now considerable evidence showing the benefits of single dose antibacterial treatment for uncomplicated urinary tract infections. If single dose therapy is to become widely used it is necessary to clarify the minimum effective dose of the most efficient drugs. This paper reports three trials in women presenting in general practice with bacterial cystitis. In each trial the patients were randomly allocated to either a five day course of oral co-trimoxazole (CTM) or to doxycycline 300 mg orally, cefuroxime 1.5 g intramuscularly or pivmecillinam 600 mg orally. Thirty-eight of 45 patients treated with doxycycline were cured, compared with 44 or 45 treated with CTM. Fourteen of 20 women given cefuroxime were cured, compared with 19 of 20 prescribed CTM. Twenty-three of 30 women treated with pivmecillinam were cured, compared with all 30 given CTM. None of these three drugs, when administered as a single dose, was as effective as a single 1.92 g or 2.88 g dose of CTM used in our previous studies in domiciliary practice. These studies confirmed, however, that single dose therapy was well tolerated, preferred by the patients and side effects were minimal.

Administration, Oral↗
PubMed1981

Cefoperazone in the treatment of severe or complicated infections.

We report the use of cefoperazone in 62 cases of serious infection, most of which occurred in patients with renal impairment. 43 severe or complicated urinary tract infections, 11 cases of pneumonia and 8 with other severe sepsis were treated with cefoperazone 1 to 2 g twice daily usually for 5 to 10 days. Of the patients with urinary tract infection, all who were symptomatic showed a rapid clinical response; 26 (61%) were cured including 11 of 16 with chronic renal failure; 12 relapsed and 5 were reinfected with a different pathogen. All of these patients were infected by organisms sensitive to cefoperazone by disc testing but in 5 of those who relapsed the cefoperazone MIC was in fact greater than or equal to 50 microgram/ml. Ten of 11 cases with radiologically confirmed pneumonia were cured with cefoperazone. 7 episodes of pneumonia were in patients with end-stage chronic renal failure (6 were on dialysis) and 1 was in a patient with acute renal failure. Seven of 8 cases with severe sepsis were cured with cefoperazone. 1 patient was withdrawn from the study when acute bronchospasm followed a 2 g intravenous dose. 2 of the successfully treated patients had functioning renal transplants, 2 of 3 with severe chronic renal failure were on dialysis and 1 had acute renal failure. Side effects included minor disturbances of liver function in 6 patients (11%), diarrhoea in 7 (13%) and marked alcohol intolerance in one, 4 patients with chronic renal failure developed a coagulation disorder which was corrected with vitamin K. None of the patients showed deterioration in renal function while receiving cefoperazone. Cefoperazone promises to be an effective drug for the treatment of a wide spectrum of severe infections in hospitalised patients including those with impaired renal function.

Adolescent↗
PubMedDate not supplied

Clinical supervision questionnaire results.

How do nurses know that they are practising in a safe, effective and professionally enriching way? And how or where do they get the professional support to develop their role when they need it, or the opportunity to share their expertise, to pass it on and expand the body of professional knowledge for the benefit of patient and client care? These questions were raised in an article on clinical supervision in Nursing Times on September 28. With the article was a questionnaire which invited readers to let the Department of Health, the UKCC and local policy-makers know how Nursing Times readers would like clinical supervision to be developed. Respondents were offered the opportunity to attend a major national conference to be held in November and one respondent would win a weekend for two at Ragdale Hall health farm, Leicestershire. This article briefly recaps the events which have led to clinical supervision being such an important and topical subject and discusses the results of the questionnaire.

Demography↗
PubMedDate not supplied

Clinical supervision for an accountable profession.

Clinical supervision has been mooted as the answer to the many challenges nurses will face in the future. In this paper, the author offers a definition of what clinical supervision is and what it will mean to the profession. She argues that nurses need to embrace the concept if they are to deliver good quality care, and outlines the central aims of clinical supervision as safeguarding standards of nursing care, developing professional expertise and delivery of quality care.

Humans↗
PubMedDate not supplied

Clinical supervision: what's going on? Results of a questionnaire.

This paper presents data obtained from a questionnaire sent to trust nurse executives in England and Scotland. While the data indicates a great deal of enthusiasm for clinical supervision, some concern must be shown for the lack of preparation and support for those involved in its implementation, a fact that will undoubtedly reflect badly in any evaluation exercise.

Attitude of Health Personnel↗