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Biomedical subjects

V Benigno

Publications and source records attributed to V Benigno.

33 records · Page 2Linked to original sources

[Urinary tract infections in the first 2 years of life. Usefulness of anamnesis in the identification of at risk subjects with malformation uropathies].

We have retrospectively studied 101 patients with an age below 24 months consecutively hospitalized, for symptomatic urinary tract infections, in the "Ospedale dei Bambini" of Palermo and subjected to radiological studies (urography and voiding cystouretrography). We have considered if the symptoms and the clinical objectivity could have given useful indications in the choice of the patients to be subjected to radiological studies. The clinical-anamnestic data have not allowed to distinguish, among patients with U.T.I., between the individuals with an abnormal conformation those with a normal one; however they have allowed to focus our attention on patients with U.T.I. through the singling out of some symptoms such as fever, vomit, cyanosis and anomaly micturition. Another datum standing out from our study is that the beginning of the symptoms in patients with U.T.I. was more precocious if at their basis there was urinary malformation.

Age Factors↗

[Hydronephrosis in childhood. Long and mid-term morphologic and functional results].

Hydronephrosis in infancy and childhood is a frequent urinary malformation and is almost always congenital. In over 80% of the cases it is due to ureteropelvic junction obstruction; in about 17%, anomalous renal vessels at the ureteropelvic junction are present. The authors analyze their experience in the surgical treatment of hydronephrosis. 360 hydronephrosis out of 335 patients were operated on from November 1971 to November 1988. 108 patients were less than 1 year old (32.2%). Primary nephrectomy was carried out only in 11 of the 360 hydronephrosis operated on (about 3%). An anterior approach and a simple dismembering pyeloplasty were performed in the majority of the cases. From the radiological point of view there was an impressive amelioration or normalization in about 92% of the cases operated on. From the functional point of view the radionuclide scan showed a normal or slightly reduced renal function in almost 90% of the cases operated on. The preoperative and postoperative radionuclide study showed a moderate increase of the renal function in the majority of the cases controlled. The authors stress the importance of prenatal ultrasound diagnosis to improve long term results of an early surgical treatment.

Child↗

[Palmar dermatoglyphics. Analysis carried out on 315 subjects of western Sicily].

The study of dermatoglyphics is one of particular diagnostic interest in many diseases, especially in the identification of some chromosomal aberration syndromes. The frequent occurrence for observation of this pathology and the need for comparison of the relevant dermatoglyphics with those of an adequate control group, caused us to carry a dermatoglyphic analysis of our population. We examined 315 normal subjects (147 males and 168 females) of Western Sicily.

Dermatoglyphics↗

[A case of transitory Fanconi syndrome associated with acute renal insufficiency and hypoplasia of the bone marrow].

The authors report a case of an eight-years old child, who presented with transient Fanconi syndrome, mild renal failure and hypoplastic bone marrow. No recognized etiology of the Fanconi syndrome was demonstrated in the patient. Laboratory data and clinical course are consistent with the hypothesis of a tubulo-interstitial lesion caused, directly or through an abnormal immune response, by an unknown etiologic agent.

Acute Kidney Injury↗

[Urinary tract malformations. Symptomatology, delayed diagnosis and urinary tract infections].

The authors examined 88 patients (32 Males and 56 Females) aged between 1 day and 13 years, suffering from urinary tract malformation, diagnosed during 1981-82 . The vesicoureteral reflux was the urinary tract malformation most frequently observed (56.81%). The patients showed symptoms of the illness within the first year of life in a percentage of 52%, while the 82% was symptomatic in 5 years. 30 months and 11 days was the average age at which the symptoms of the illness appeared, while the diagnosis was effected at an average of 47 months and 15 days. The authors pointed out the reasons of this diagnostic delay and the possibilities of filing it up. Urinary tract infection was found at the time of hospitalization in a percentage of 55%. The authors described the kind of germs isolated and their resistance to the most common antibiotics.

Age Factors↗

[Sugiura's operation in the treatment of hemorrhaging esophageal varices].

Rebleeding, the long time high occurrence of encephalopathy and the impairment of hepatic function in the successful cases have led to increasing dissatisfaction in the last years with portasystemic shunt procedures. In the past 12 years we have operated on 14 children for bleeding esophageal varices using the Sugiura procedure (esophageal transection with paraesophagogastric devascularization); in two cases the entire procedure was performed through the thoracic approach. We had no mortality. Complications include bleeding in the early postoperative period in two children and partial leakage from the esophageal suture in two others. Patient follow-up has been between 16 months and 11 1/2 years with an average of 6 1/2 years. The long term controls have been gratifying in 12 patients with disappearance of the varices and no evidence of rebleeding, esophageal strictures, gastroesophageal reflux, encephalopathy or impairment of the hepatic function; in two other patients the operations was unsuccessful. In our opinion the Sugiura procedure should be the elected operation in the surgical treatment of esophageal varices bleeding in pediatric age, after an attempt with sclerotherapy.

Child↗

[Ring chromosome 4 in twins].

A case of ring chromosome 4 in an eleven months old male child with severe mental retardation, microcephaly and craniofacial anomalies is described. The karyotype was: 46,XY, r(4) p16----q35). The patient shows only few elements of the Wolf syndrome, whose phenotype is observed in most of the other cases with analogue karyotype.

Abnormalities, Multiple↗

[48,XXYY syndrome in a 4-year-old subject].

The authors present a four years old boy with genitalic infantilism, mild mental retardation and karyotype 48, XXYY. This rare gonosomic aneuploidy is exceptionally discovered during childhood because it is diagnosed in most of cases after puberty for its phenotype similar to the Klinefelter's Syndrome.

Child, Preschool↗

[Laboratory parameters as a guide for the radiologic study of infections of the urinary tract in childhood].

Forty-nine children with urinary tract infection aged between 15 days and 10 years were studied. Thirty-three of them (67.3%) had urinary tract malformations. We valued the following parameters: a) White Blood Cells; b) Leukocyte differential; c) ESR at the first hour; d) CRP; e) Concentration ability; f) Body temperature. We wanted to investigate the usefulness of these parameters to predict which patients should be studied by X-ray of urinary tract. Single parameters did not prove very sensitive; the highest correlations were found with ESR and CRP, which were positive in 76% of the cases of malformations. Furthermore we valued the sensitivity and specificity of the tests grouped together: the highest values of sensitivity (97%) and specificity (31%) were obtained coupling the ESR and concentration ability.

Blood Sedimentation↗

[Results of the surgical treatment of primary obstructive megaureter in the child].

Primary obstructive megaureter (P.O.M.) is a dilatation, different in size, of upper urinary tract without reflux and secondary to a functional obstructive malformation of terminal segment of ureter. Infection and renal function impairment complicate P.O.M. in a rather high percentage of cases. In Authors' experience, in about 22% another urinary malformation and in more than 8% an extraurinary malformation are associated. Authors' experience in the treatment of 119 P.O.M. (102 patients) is reported. 14 P.O.M. (9 patients) were not operated on. In 104 megaureters (92 patients) an ureteric reimplantation with shortening and tailoring without preoperative temporary urinary diversion was carried out. In 4 megaureters a V.U.R. and in another 4 an ureteric stenosis taken place as postoperative complications. In 96 ureters (92.3%) positive results were obtained with normalisation or impressive improvement of upper urinary tract and improvement of renal function.

Child↗

[Proposed functional classification of urination disorders of a neurologic nature in children].

It is absolutely necessary for all individuals engaged in the care of pediatric patients with neurogenic voiding dysfunction to have a useful means of categorizing the patient's problems. Actually the most accepted classifications are the "urodynamic" proposed by Krane and Siroky and the "functional" proposed by Wein. These Authors present two different approaches to accomplishing the same purpose: namely, directing the appropriate therapy for the patient's problems. In the authors opinion, from a diagnostic and therapeutic standpoints, a working understanding of both of these classifications seems advisable. In this paper the authors present a functional-urodynamic classification of neurologic voiding dysfunctions in pediatric age, clinically and therapeutically useful.

Child↗

[Hydronephrosis in infancy and childhood].

Hydronephrosis in infancy and childhood is almost always congenital. In 80% of the cases is due to ureteropelvic junction obstruction, in 20% is due to anomalous renal vessels sometimes associated to ureteropelvic junction obstruction. The authors analyze their experience in the surgical treatment of this urinary malformation during a ten years period (1971-1981). 119 hydronephrosis out of 105 patients were operated on. The surgical procedures were successful in 93% of the 119 operated hydronephrosis and in 80% of the giant hydronephrosis. Primary nephrectomy was carried out in only 5% of the operated hydronephrosis (6/119). The Authors stress the importance of early diagnosis to improve surgical results.

Child↗