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Biomedical subjects

V B Matiushichev

Publications and source records attributed to V B Matiushichev.

At least 19 recordsLinked to original sources

[Age-related specificity of the blood picture in females with diffuse toxic goiter].

The factor analysis was used to examine a relationship of a number of clinical and blood biochemical parameters to the level of triiodothyronine (T3), tyroxine (T4), and thyroid-stimulating hormone (TSH) in third-fourth degree diffuse toxic goiter (DTG) in females aged 17-45 and 46-58 years. It was established that the changes in T4 and TSH values were coordinated and T3 values varied independently. In DTG, the concentration of T4 correlated with that of K' and the levels of TSH and T4 correlated with those of cholesterol only in the age group less than 45 years. The specific features of the leukogram were associated with the level of T4 in females aged under 45 years and with that of TSH in females over 45 years of age. In DTG, there was a drop in blood TSH concentrations only in the group of 46-59 years.

Adolescent↗

[The specific distribution of erythrocytes and blood platelets according to the volume of cells in different-age children].

The reference volumes of erythrocytes and blood platelets were evaluated for different age groups of children. The mean volume of cells and the parameters of its distribution, i.e. SD, As and Ex, were found. The mean volume of erythrocytes and the value of positive Ex for the volume of blood platelets were shown to be reliably higher in adults. The investigated blood parameters in children were proven to depend in children on their age and sex. It was concluded that the mentioned peculiarities should be considered in the practice of clinical laboratory examinations.

Adolescent↗

[Correlation of erythrocyte electrophoretic mobility and the velocity of their sedimentation in the norm and renal pathology].

It was established, while making blood tests for healthy males and for patients with glomerular nephritis at exacerbation, that there is a statistically reliable interrelation between the erythrocyte electrophoretic mobility and their sedimentation velocity. Its nature is subject to modifications as the functional body state and the investigated range of concurrently altering parameters are changing. Such hierarchy, in neuropathy, can be also the case at the level of mean parameters; and in health, it can be observed only as a conjugated reconstruction of the erythrocyte population structure.

Adolescent↗

[Potentialities of enhancing the diagnostic efficiency in registering the electrophoretic mobility of erythrocytes].

The potentialities of optimizing the clinical use of electric surface properties of erythrocyte blood samples were investigated. The ordinarily used parameter of the eletrokinetic erythrocyte potential based on the mean value of electrophoretic mobility was shown to be inaccurate and low informative. Asymmetry factor and erythrogram excess (distribution parameters) are recommended for use to enhance the adequate evaluation of changes in the above parameter and to make it diagnostically more effective. Principles of interpretation of changes' results are described.

Cell Movement↗

[The efficiency of endoscopic therapy of duodenal ulcer by laser copper emanation].

A factor analysis of 16 clinical-anamnestic indices was used in order to estimate their significance for the assessment of efficiency of high energy endoscopic laser therapy of duodenal ulcers with yellow, green and yellow-green emanation of the copper laser. It was demonstrated that the rate of ulcer cicatrization was dependent on its size, course of the ulcer disease, manifestations and steadiness of pain syndrome, but the morphological severity of the injury did not correlate with its clinical symptoms, and duration of the remission period after the phototreatment was mainly determined by the color of the laser beam.

Copper↗

[Regulation of electrokinetic properties of human blood erythrocytes following exposure to emotional stressor].

Using the factor analysis, we studied the influence of psychoemotional strain, experienced by students under taking examinations, on the electrophoretic mobility of their erythrocytes. Under stress condition, redistribution of shares of cells with different mobility occurs, directed to the maintenance of the optimal value of the index average level in the total pool of erythrocytes of an individual. Under stress, five factors, taken in different combinations, participate in the control of erythrokinetic properties: those of restriction of cell accumulation with abnormal mobility, and of the population quantity heterogeneity control, in addition to factors of total functional condition, emotional tension, and individual psychological steadiness of students before examination. The expression and character of stress influence on the state of erythrocyte population depend on the intensity of the functional load of the organism.

Cell Movement↗

[Additional potentialities of using blood cell characteristics for diagnosis of nonspecific ulcerative colitis].

The potentialities of increasing the resolving capacity of standard hematological parameters used for the diagnosis of chronic nonspecific ulcerative colitis were investigated. The mean volume of erythrocytes decreases and the shape of population erythrogram is modified in this disease. White blood is characterized by qualitative changes (mean cell volume and parameters of its distribution for neutrophils lymphocytes, and monocytes). Consideration for the corpuscular volume of these cells helps differentiate between slight, medium, and severe chronic nonspecific ulcerative colitis.

Adolescent↗

[Effect of strophanthin on the electrophoretic mobility of blood erythrocytes in adults and children].

As assessed by changes in the erythrograms asymmetry coefficient, selectivity of the strophantin effect on cell populations with different mobility and age specifics of reciprocal responses, was revealed in adult subjects and in children. The data obtained suggest existence of difference in quality of functional condition of the erythrocytes with normal as well as reduced mobility in children and in adults.

Adult↗

[Dependence of the size of leukocytes on their number in human blood].

An interaction was shown to exist among the quantities of neutrophiles, lympho- and monocytes in circulation and characteristics of their corpuscular volume. The correlation embraces all the leukocyte classes, being apparent in indices of separate classes as well as on the intertype level. Such a co-ordination is involved in maintenance of the normal microcirculation level and manifested in a series of intra- and intertype correlations of relative content and parameters of the corpuscular volume distribution of the cells.

Adolescent↗

[Relations between number and volume of erythrocytes and leukocytes in the human blood].

Total concentration of erythrocytes and leukocytes, a relative contents of neutrophils, lymphocytes, monocytes, average volume of these types of cells, were determined in humans. Changes in the cell indices seem to be correlated and sex-dependent. Thus, erythrocytes and leukocytes are correlated in their contents and volume characteristics. A control mechanism seems to exist in humans, involving microcirculation in capillaries.

Adult↗

[Electrophoretic mobility and oxidizing status of rat blood erythrocytes at scald trauma].

On model of scald trauma the correlation of electrophoretic mobility of rat blood erythrocytes with intensity of lipid oxidation of erythrocyte membranes and with activity of catalase were studied. It is shown that in dynamics of scald disease development the erythrocyte mobility decreases, the velocity of oxidizing ability of their lipids increases and the protective action of blood antioxidation system is blocked. It is found that there is a close dependence between the level of oxidative processes and electrogenic properties of erythrocytes at the height of manifestation of scald toxaemia. A conclusion was made that the oppressing influence of increasing lipid oxidizing ability a on electrokinetic potential of erythrocytes is of a threshold nature and is realized through change in the membranes' state of these cells.

Animals↗

[High-energy laser therapy of stomach ulcers].

Efficacy of local therapy with copper laser was tried in 105 patients with drug-resistant gastric ulcers. The exposure to yellow-green light each other day brought about scarring of the defects for 15.4 +/- 2.0 days, on the average. In the two-times a week regimen the healing was reached for 24.1 +/- 2.3 days. Separate use of yellow and green light proved highly effective, 42.5% of patients were in remission for 5 years. Frequency of the exacerbation before the treatment and duration of the remission were unrelated. Not a single case of malignant transformation of the ulcer was registered.

Adolescent↗

[Sex differences in the electrokinetic properties of the erythrocytes in normal children and in iron-deficiency anemia].

The electrophoretic mobility of children blood erythrocytes in norm and with iron-deficiency anemia was studied. The age peculiarities and sex specificity of this index was revealed, demonstrated chiefly by dynamics of shape of its distribution curve reflecting a ratio of cell subpopulations with different electrokinetic potential. The state of anemia is accompanied with modification of histogram profiles of both individual and group cell mobility, with patterns of changes also depending on the child sex. The obtained data suggest that at children iron-deficiency anemia the structure or functional status of erythrocyte membrane are changed, but the pathological process does not eventually involve all the populations of circulating erythrocytes.

Aging↗

[The mechanisms of changes in erythrocyte electrophoretic mobility in nephropathology].

A correlation between erythrocyte electrophoretic mobility (EEM) and a complex of clinico-biochemical indices in the blood of patients with chronic pyelo- and glomerulonephritis was studied. It is established that the EEM homeostasis as a whole, comes to the redistribution of cell subpopulation parts with high and low mobility. For keeping stability of EEM, of great significance in the control patients is the total protein content in the plasma, whereas in patients with kidney pathology of primary importance is the level of neutrophils.

Cell Movement↗