Biomedical subjects

V B Maksimenko

Publications and source records attributed to V B Maksimenko.

20 records · Page 2Linked to original sources

PubMedDate not supplied

[Hypokinesia, nutrition and lipid metabolism. Lipids and lipoproteins in the blood].

Long-term hypokinesia of August and Wistar Albino Glasgow rats caused some alterations in composition of total lipids and cholesterol esters both in blood serum and in individual lipoprotein fractions. The most distinct alterations were the following ones: I. increase in content of very low density lipoproteins (VLDL) and of low density lipoproteins (LDL), 2. decrease in the level of cholesterol esters in blood serum with a simultaneous increase of their content in VLDL and LDL as well as with alteration of their composition, 3. decrease of triglyceride content in VLDL and increase--in LDL, exhibiting the alteration in activity of lipolytic enzymes. Functional activity of muscles was very important for maintaining of the normal level of blood serum lipids and lipoproteins.

Animals↗

PubMedDate not supplied

[Lipid metabolism disorders in the long-term consumption of a diet with wheat gluten as the protein source].

The two-month feeding of male August rats with the wheat gluten-containing diet led to an increase in the blood level of low density lipoproteins (LP), free and esterified cholesterol, free fatty acids and acylglycerides. Meanwhile the content of very low density LP and high density LP declined. Cholesterol esters showed a rise in the content of cholesterol linolenate, cholesterol oleate and cholesterol palmitate. Liver microsomes demonstrated an increase in the amount of arachidonic and eucosotrienic acids. The shifts cited were largely determined by the changes in cholate formation and bile excretion, which were marked by the reduced levels of tauro- and glycocholic acids, increased amount of phospholipids and free fatty acids in the bile, and decreased content of cytochromes P-450 and b5 in hepatocyte microsomes.

Animals↗