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Biomedical subjects

V Amato Neto

Publications and source records attributed to V Amato Neto.

At least 307 records · Page 17Linked to original sources
PubMedDate not supplied

[Experimental evaluation in mice of vitamin B complex repellent activity against Culex quinquefasciatus].

One untested but widely held opinion in Brazil is that oral use of vitamin B complex is useful as a mosquito repellent. We exposed Balb-C mice to a large number of Culex quinquefasciatus females, after giving vitamin B complex to mice (drops by mouth). There was no difference between mice attractiveness to mosquitoes in the vitamin B group compared to normal, but very few of the females bite mice in both groups, so the experiment was inconclusive. We suggest further experiments in this subject, using other models were the animals are more attractive to mosquitoes.

Animals↗
PubMedDate not supplied

[Characterization of Trypanosoma cruzi strains isolated from patients with heart transplantation].

Three strains of Trypanosoma cruzi were isolated in Chagas' disease patients transplanted for heart failure. These strains were studies in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with those of the standard strain Y. The strains had differences in the studies parameters, but there was no clear relationship between them and the post-transplant evolution of the patients, probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model.

Adolescent↗
PubMedDate not supplied

[Casual influence of the stimulation of macrophage production by proteose-peptone, in the experimental infection of mice by Plasmodium berghei].

Proteose-peptone is a known powerful stimulator of macrophages. This stimulation was studied in an experimental malaria infection model, using Plasmodium berghei in mice. Parasitemia and mortality did not change in stimulated animals, and macrophage mobilization, contrary to other published papers, was not effective to increase either parasite levels in the blood or mortality.

Animals↗
PubMedDate not supplied

[Human pulmonary dirofilariasis acquired in Brazil: report of a case].

We report the second published case of human dirofilariasis acquired in Brazil. The patient had two pulmonary coin lesions seen in conventional chest roentgenogram and confirmed as solid round nodules by computerized X-ray chest scan. Diagnosis was done by surgical removal of one of the lesions and anatomopathological study of tissue removed.

Aged↗
PubMedDate not supplied

[Effect of quinolones on mice experimental infection by Plasmodium berghei and their possible therapeutic usefulness].

The search for new antimalarial drugs is important for many reasons, specially because of the resistance of plasmodia. Some clinical and laboratory studies have recently indicated that quinolones, currently in use for treatment of bacterial infections, have antimalarial activity. So, we evaluated the possible action of ciprofloxacin, norfloxacin, ofloxacin and pefloxacin in mice experimentally infected by Plasmodium berghei, by the oral route. Taking into account parasitemia and mortality, we came to conclusion that these drugs are not effective, as judged by the methods used.

Animals↗
PubMedDate not supplied

[Congenital malaria: report of a case and considerations about the subject].

We report a case of Plasmodium falciparum malaria in a 21 day old child that was born from a mother that developed clinical signs of falciparum malaria just after giving birth and died. Transmission could have occurred either by the transplacental route or by maternal blood reaching the child during the childbirth. Literature review shows that malaria should be considered as a cause of a febrile disease in the newborn, particularly if there is a low birthweight and the newborn is a child of a woman coming from an endemic malaria region.

Adult↗
PubMedDate not supplied

[Current risk of AIDS transmission by transfusion].

Transmission of HIV infection by blood transfusion was first reported in 1982. By systematic blood testing of the donors the risk of transmission of HIV by blood transfusion has been diminished. In the USA the risk to be infected by HIV with blood that was tested negative is about 1/60.000. In Brazil this risk is much greater: it is believed that in São Paulo the HIV infection occurs in between 1/2500 and 1/15000 of transfusions.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Serological evaluation for human immunodeficiency virus (HIV) and for hepatitis B (HBV) among candidates who have passed the admission tests at a hospital institution in São Paulo].

Health professionals (HP) are frequently exposed to accidents with materials contaminated with blood and/or body fluids, thus representing a population at risk for the acquisition of human immunodeficiency virus (HIV) and hepatitis B virus (HBV). PURPOSE--To determine the prevalence of HIV and HBV infection among HP admitted to the University Hospital, Faculty of Medicine, University of São Paulo (UH-FMUSP), and to identify the possible sources of contamination. METHODS--A total of 345 HP who sequentially passed the hiring examination at UH-FMUSP from March 1 to June 23 1993 were evaluated and compared to 2521 blood donors using serologic tests for the detection of AgHBs and total anti-HBc of HBV. The ELISA method was also used for HIV-1, with subsequent confirmation by Western blot. Questionnaires were distributed to the HP for the identification of possible sources of contamination. RESULTS--Positivity to HIV-1 was 0.48% for HP and 0.23% for blood donors, and positivity to HBV was 8.89% and 6.17%, respectively. CONCLUSION--There was no statistically significant difference in the results of the serologic tests for HIV and HBV detection between the two groups, even taking into consideration the different professions of those who work in the health area and their potential exposure to blood and secretion.

Acquired Immunodeficiency Syndrome↗