Biomedical subjects

V Alvarez Angel

Publications and source records attributed to V Alvarez Angel.

23 records · Page 2Linked to original sources

PubMed1989

[Anti-endomysium antibodies: new serological markers for the diagnosis and follow-up of patients with gluten-sensitive enteropathy. Preliminary study].

The authors value the parameters of diagnostic efficacy in a preliminary study of anti-endomysium antibodies (EmA), in the diagnostic and follow-up of patients with gluten sensitive enteropathy. The study was made with 84 subjects distributed into four groups. Group I consisted of 21 patients with gluten sensitive enteropathy (GSE) who were eating gluten at the time of diagnosis. Group II consisted of 20 patients with gluten sensitive enteropathy with different periods of time of gluten free diet. Group III consisted of 16 subjects with non-evolutive neuropathies and without intestinal disease. This group was considered as controls. Group IV consisted of 27 patients with toddler diarrhoea. The sensitivity, specificity, positive predictive value, negative predictive value and efficiency were 100%.

Autoantibodies↗

PubMed1989

[The role of IgA and IgA antigliadin antibodies in the diagnosis and management of celiac disease].

The authors reports the results of ELISA IgG and IgA antigliadin antibodies measurements in a study of 271 serum samples proceeding from celiac patients (with and without gluten containing diet) and control subjects. IgA antigliadin antibody measurement had the most specificity and positive predictive value, IgG antigliadin antibody measurement had the most sensitivity and negative predictive value. Our results point out that antigliadin antibodies are helpful in the diagnosis and management of celiac disease. Un the same manner, antigliadin antibodies are helpful to evaluate the adherence of patients to gluten-free diet.

Celiac Disease↗

PubMed1987

[Bronchial provocation test with dermatophagoides in the diagnosis of infantile asthma: sensitivity, specificity and reproducibility].

The purpose of this study has been to prove if the lung is the target organ of an allergen against which a biological hypersensitivity, by means of skin test and RAST, has been found; comparing score Foucard diagnostic with inhalatory test result. At the same time, checking test specificity and reproductibility. Fourty children, both sexes aged between 6 and 14 years diagnosed of bronchial asthma divided in two groups were studied. First group included 31 children with hypersensitivity to dermatophagoides and second group was control group including 9 children. The test with dermatophagoides was performed in both groups according to Cockcroft method. The parameters which indicated test positivity were 20% fall in FEV1 for early response and 40% fall in PERF for late response. The results obtained show 83.9% positive tests with 80.6% early responses and 45.2% positive late response. The specificity and reproductibility were of 100%.

Adolescent↗

PubMed1986

[The metacholine test for the study of unspecific bronchial hyperreactivity in childhood].

To compare the results between asthmatics with different etiology, to study the bronchial reactivity in nonasthmatics, and verify if 8 mg/ml is a good limit of differentiation between asthmatics and healthy ones, a methacholine test was performed in fourty children distributed in four groups: group I (atopic asthmatics); group II (nonatopic asthmatics); group III (nonsymptomatic brothers of asthmatics) and group IV (healthy controls without IV. The means values of PC20 FEV1 were: Group I, 0.42; familiar antecedents of asthma). In groups I and II were all positives, in group III two cases (20%) and none in group II, 0.64; group III, 7.37, and group IV, 16.4 mg/ml. It is verified pathogenic meaning of the bronchial hyperreactivity in the asthma independently of its etiology, and the satisfactory differentiation between asthmatics and healthy ones with 8 mg/ml as limit of positivity. It is suggested the realization of extensive studies in brothers of asthmatics to determine the usefulness of the test as screening in such children.

Adolescent↗

PubMed1981

[Holt-Oram syndrome. Presentation of two cases (author's transl)].

Authors present two new cases of the Host-Oram syndrome in the same family, characterized by the association of cardiac anomalies and the upper members, both aspects varying greatly, transmissible with a dominant autosomal character. In one case there was unilateral renal agenesis, association described for the second time in literature. Data provided by other authors uphold this, as far as the variable and generally progressive penetration of the syndrome are concerned, as well as the frequent association with other diverse malformations.

Abnormalities, Multiple↗