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Biomedical subjects

V A Samsonov

Publications and source records attributed to V A Samsonov.

At least 37 records · Page 2Linked to original sources
PubMed1990

[Tigazon in the therapy of patients with circumscribed scleroderma].

Therapeutic efficacy of tigason in local scleroderma has been demonstrated in 50 patients. The drug has proved effective at all active stages of the process. Its action is favorable in sclerosis and in deep infiltration foci, when traditional therapy, including cuprenil, are of poor efficacy. Tigason altered the course of the disease, making it more benign. The authors recommend this drug, particularly for patients with intolerance of or resistance to the traditional therapy.

Adult↗
PubMed1989

[Dynamics of immunologic indices in patients with Kaposi's sarcoma during treatment with the preparation leakadine].

Changes in the immunologic parameters of 39 patients with Kaposi's sarcoma over the course of leakadin therapy were under study, i. e. total leukocyte and lymphocyte counts, immunoregulatory cells in spontaneous and complementary rosette formation, and in that with monoclonal antibodies. The therapeutic efficacies and immunostimulating activities of prospidin and leakadin, a new Soviet drug, are compared. Besides sufficient therapeutic efficacy, leakadin has shown a manifest immunocorrective effect, increasing the counts of CD2+ and CD3+ cells, i. e. of the total T-lymphocyte pool (including the "young" cells) and, consequently, of its mature fraction, CD4+ and theophyllin-resistant T-lymphocytes, CD8+ cells; this fact recommends the drug for the treatment of patients with Kaposi's sarcoma. Since the immunomodulating effects of prospidin and leakadin are ambiguous, their combinations are advised for the treatment of Kaposi's sarcoma.

Adjuvants, Immunologic↗
PubMed1989

[The effectiveness of treating patients with malignant skin lymphoma and Kaposi's sarcoma studied via polyamines].

Lymphoproliferative diseases of the skin and Kaposi's sarcoma were found to involve high excretion of polyamines. Therapy with reaferon combined with prospidine and indomethacin improved the clinical course of the process and was associated with a decrease of polyamine excretion. Measurement of the urine polyamines may be used for the assessment of the treatment efficacy in malignant lymphomas of the skin and in Kaposi's sarcoma.

Adolescent↗
PubMed1989

[Skin lesions in diabetes mellitus].

The characteristics of cutaneous manifestations in diabetes mellitus are presented. The clinical features of the skin lesions are described in relation to the severity of metabolic disorders. The clinical and biochemical features of Necrobiosis lipoidica, its classification and methods of treatment are detailed.

Adolescent↗
PubMed1989

[Ocular melanoma metastases to primary liver carcinoma].

Two days after hospitalization, a 64-year-old patient with chronic coronary heart disease developed jaundice. He was diagnosed as having primary liver cancer. During the past 3 years, the patient had lost sight in the right eye. He died of hepatic and cardiac failures 8 days following hospitalization. Pathoanatomic examination revealed massive poorly differentiated carcinoma of the liver and right ocular melanoma (spindle cell one). The latter had metastasized into the episcleral tissue of the same eye, liver, and hepatic tumor tissue, and liver carcinoma had invaded the organ itself and pleura.

Eye Neoplasms↗
PubMed1989

[Comparative analysis of the clinical effectiveness of reflexotherapy and psychopharmacotherapy in the treatment of neurotic disorders in dermatology patients].

Comparative studies on the efficacy of a multiple-modality treatment of patients with chronic dermatoses (atopic dermatitis, eczema, psoriasis), including reflexotherapy (RT) and drug psychotherapy (DPT), have shown high clinical efficacy of RT in cases with hysterical and moderately expressed anxiety-depressive disorders and of DPT in pronounced depressive hypochondriac disturbances. Unlike DPT, RT has not been associated with side effects. Clinical results have been confirmed by the data of comprehensive clinical and psychological examinations of the patients in the course of treatment.

Acupuncture Therapy↗
PubMed1988

[Pathologo-anatomical characteristics of lung cancer (analysis of 2000 autopsy records 1981-1985)].

2000 autopsy protocols have been scrutinized for 1590 males and 410 females who died of lung cancer in Leningrad and Petrozavodsk in 1981-1985. The findings, compared to those for 1953-1957, evidence for older age of the population at the terminal stage of the disease, more frequent cases of associated primary tumors (by 2.19%), greater proportion of squamous and bronchioloalveolar cell carcinoma (a rise from 24.6 and 1.2 to 45.7 and 3%, respectively). The proportion of small cell carcinoma, on the contrary, tended to decrease (from 48.4 to 22.6%). Lung cancer metastases used to emerge with similar frequency in patients subjected to radical operation and those surgically untreated. In 41 out of 144 lethal intraoperative and postoperative outcomes metastases were found to involve the other lung, viscera, mediastinal and distant lymph nodes. Further progress in the diagnosis of metastatic spread and adequate preoperative examination of the patients are thought to promote a valid choice of patients to be operated on.

Adenocarcinoma, Bronchiolo-Alveolar↗
PubMed1988

[Malignant fibrous histiocytoma of the esophagus].

The patient aged 60 underwent extirpation of the thoracic oesophagus followed by esophagogastroplasty and splenectomy. There was a polyp-like neoplasm 12 cm long and 3 cm in diameter on a crus originating from the esophageal wall and diagnosed histologically as a malignant fibrous histiocytoma infiltrating muscular coat at the site of the crus. The patient died of suppurative mediastinitis 8 days later.

Diagnosis, Differential↗
PubMed1988

[Electrophysiological research on pain and itching in the clinic].

To study the central mechanisms of pain and itching, the authors performed electroencephalographic (EEG) examination in acupuncture-treated patients with diffuse neurodermatitis (n = 43) and trigeminal neuralgia (n = 25). The most characteristic EEG finding was increased synchronization of the cortical rhythm. The revealed EEG features point to the functional involvement of the thalamocortical system in the development of pain and itching. Changes of clinical and electrophysiological parameters in the course of acupuncture treatment is an additional evidence of the morphofunctional unity of the development of pain and itching.

Acupuncture Therapy↗