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Biomedical subjects

V A Rogozina

Publications and source records attributed to V A Rogozina.

8 recordsLinked to original sources
PubMed2003

[Comparative efficacy of mezakol and sulfasalazine in treating chronic relapsing ulcerative colitis].

This research testifies to the fact that it is more preferable to use mesacol than sulfasalazine in treatment of common forms of ulcerative colitis of light and average severity. Mesacol acts faster in arresting inflammations in proximal parts of the larger intestine. One can assume that the pH-dependent release of 5-aminosalicylic acid in these forms of the disease suffers less than the destruction of the diazo link by the anaerobic microflora, due to which a higher concentration of the preparation is formed in the large intestine. Another alternative explanation can be the dose-dependent effect. Thus, 2.4. g of mesacol correspond to 6 g of sulfasalazine. The dose of sulfasalazine was smaller in our study. Mesacol had no advantages over sulfasalazine in treatment of distal colitis, which can and must be treated with rectal introduction of corticosteroids and 5-aminosalicylic acid preparations. Thus, mesacol must be reserved for treatment of patients with common ulcerative colitis of light and average severity in case of intolerance to sulfasalazine or impossibility to increase the preparation dose over 4 g/day. Its efficiency and price make the preparation available for most patients and patient care institutions.

Adult↗
PubMed2002

[Absorption function of the large intestine in patients with nonspecific ulcerative colitis].

Colon absorption function was examined in twenty fife patients with active non-specific ulcerative colitis (15 persons with the distal form and 10 with left-side form investigate by rectal antipyrin test. The state of absorption was estimated on duration of antipyrin half-absorption, on attainment of its maximal concentration and on level of its salivary concentration. Most of patients (n = 19) with active non-specific ulcerative colitis had disorders of colon absorption. This was demonstrated by reduced antipyrin absorption and decreasing amount of absorbed material. But in 6 patients with expressed destructive-inflammatory processes the antipyrin absorption was intensified. In patients with ulcerative colitis the disorders of colon antipyrin absorption depend on activity of inflammatory processes.

Adult↗
PubMed2002

[Disorders of hemostasis in clinical picture and pathogenesis of inflammatory diseases of the colon (literature review)].

Hemostatic disorders are involved in the pathogenesis of inflammatory large intestine diseases. Both thrombocytes and humoral coagulation factors are involved in this process. An attempt to correct these disorders will allow not only to declare a new approach to the treatment of inflammatory large intestine diseases but also to clarify their role in the occurrence and persistence of an active inflammation during these diseases.

Blood Coagulation Disorders↗
PubMed2002

[Hemorrhoids].

Hemorrhoids is believed by right to be one of the most widely spread human sufferings ranking first among diseases of the rectum and large intestine. According to the data of numerous studies devoted to this problem, from 2.9 to 27.9%% of population of different countries suffer from hemorrhoids. Most authors agree that men suffer from hemorrhoids more often than women do and that its frequency increases with the aging. For the sake of justice, it is necessary to note that some researchers insist that men and women suffer from this disease equally often but that men ask for medical care 1.5 times more often.

Female↗
PubMed2001

[Morphometry in the diagnosis of colon villous polyps].

Endoscopic biopsies were carried out in 62 patients with colon villous adenomas and 28 patients with colon adenocarcinomas. Differential-diagnostic schemes of evaluation different morphological versions of colon villous adenomas were used for processing results of hystological investigations. These schemes were offered by G.G. Avtandilov et all. Multifactorial analysis of diagnostic features showed a possibility of transition from villous adenoma to adenocarcinoma.

Adenocarcinoma↗