Malignant melanoma presenting as renal tumor.
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Biomedical subjects
Publications and source records attributed to V A Politano.
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Subtracted bladder pressure recording is the ideal method to diagnose bladder instability in supine and erect positions. Uroflowmetry demonstrated higher peak flow rates in our stable bladder group. Lateral cystourethrography showed a higher degree of urethral hypermobility in the same group. We believe that cystometry with subtraction is still the cornerstone in the evaluation of these patients. Uroflowmetry and lateral cystography may add some information and deserve further investigation in a large number of patients. Intravesical pressure alone, external urethral sphincter electromyography, and static urethral pressure profilometry were of no value in the evaluation of our patients.
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We are reporting on a 23 year old white male with neurogenic bladder disease secondary to spinal cord injury, who recently was discovered as having a primary transitional cell carcinoma of the posterior urethra. He is the youngest patient with neurologic involvement of the lower urinary tract presenting a malignant urethral tumor.
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Ten patients, three to fifteen years postvasectomy, underwent vasovasostomy. Using 2-0 nylon, stents were brought to the scrotal surface. Vas anastomosis was accomplished with a single transmural layer of 6-0 or 7-0 proline or chromic sutures under loupe magnification. Stents were removed in seven to ten days. After two years, a pregnancy rate of 70% was achieved, comparing favorably with other more difficult operative techniques.
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A case of leiomyosarcoma of the prostate is presented. The patient was successfully treated with transperineal radon seed implantation and external irradiation. The five-year, disease-free survival suggests that such patients can benefit from this therapeutic approach.
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A case of angiosarcoma of the right corpus cavernosum with direct extension to the bladder, prostate, and seminal vesicles and metastasis to brain, liver, and cheek is presented, and the literature is reviewed.
We herein review the last 29 patients with priapism treated at our hospitals with respect to the physiology and pathophysiology of erection and priapism, respectively, and present a rational approach to the management of priapism. Emphasis is given to the corpus cavernosum to corpus spongiosum shunt with a vascular anastomosis technique.
The relative effectiveness of different combinations of estrogen therapy and radiation therapy against the R-3327 prostatic adenocarcinoma of the Copenhagen rat was studied. Because of similar actions of estrogens and radiation in the cell cycle, and possibly antagonistic effects reported in the clinical literature, we looked for an antagonism between these two therapeutic modalities. Radiation therapy consistently showed a greater tumor inhibitory effect than estrogen therapy alone at the dose tested. Combinations of radiation therapy with hormonal manipulation did not appear to show a greater inhibition of tumor growth than radiation therapy alone. There also did not appear to be an antagonistic effect between these two modalities in this system.
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