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Biomedical subjects

V A Orlov

Publications and source records attributed to V A Orlov.

At least 73 records · Page 4Linked to original sources

[Hemodynamic structure of pressor reactions to vasoactive substances].

In cats, similar changes of the blood pressure had different hemodynamic structures under the influence of catecholamines or angiotensin. Adrenalin was able to evoke a pressor response by means to either caridac or vascular factor. In the former case, the increase in the cardiac output was induced both by an increasing blood flow towards the heart and by an additive outflow of the blood from the minor to the major circulation; in the latter case, the increase in the general peripheral resistance entailed a decrease in the cardiac output in spite of the augmentation of the venous return which determined a delay of the blood in the minor circulation. The latter variant of interrelationships among hemodynamic parameters can occur under the influence of noradrenaline as well. A combined similarly rendered participation of the cardiac and the vascular factors in the increasing the blood pressure occurs under the influence of angiotensin and sometimes of noradrenaline. The participation of cardiac output in the pressor response may depend on hemodynamic shifts in the minor circulation which either limit or facilitate, or leave unchanged the rate of increment of the cardiac output.

Angiotensin II↗

[Cytophotometric study of the AChE-containing nerve cells and fibers of the rabbit heart after electrostimulation of the area hypothalamica posterior].

By means of cytophotometry and a computer in the cardiac intramural neural plexus of 17 experimental and 17 control rabbits acetilcholine esterase (AChE) activity (revealed by Karnovsky--Roots' method) was investigated. It was stated that a prolonged electrostimulation of the area hypothalamica posterior (AHP) produced statistically significant 2-fold decrease of AChE activity in the cardiac neural cells and fibres. When the stimulation of AHP was stopped, the decreased enzymatic activity was observed for the first two weeks, then by the end of the 4th week it again reached its control level. The results of the work were discussed in view of possible disorders of regulating vegetative-trophic effects of the posterior hypothalamus on innervative and executive tissue elements of the heart.

Acetylcholinesterase↗

Significance of angiography of the pancreas in the diagnosis of chronic pancreatitis.

The author made angiographic studies of pancreas in 94 patients with chronic pancreatitis. In all patients there were alterations in angiographic architecture of the pancreas. Ten angiographic signs were described which in combinations of three or more, were deemed sufficient for diagnosis of chronic pancreatitis. Wide use of angiography of pancreas is recommended for diagnosis of chronic pancreatitis as well as for morphological assessment of the pancreas.

Adult↗