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Biomedical subjects

V A Moyer

Publications and source records attributed to V A Moyer.

23 records · Page 2Linked to original sources
PubMed1992

Hepatitis B screening in pregnancy: practical aspects.

Hepatitis B may be acquired at birth from a mother who is a chronic carrier and may result in debilitating liver disease later in life. Screening of pregnant women and preventive measures have been shown to be clinically effective and at least marginally cost-effective. The Centers for Disease Control recommends universal screening of pregnant women. Cost-effectiveness has been evaluated using estimated costs and assuming patient compliance. The practical aspects of screening a high-risk population are described in the context of a single program, with discussion of excess costs and problems with implementation.

Carrier State↗
PubMed1990

Total and differential leukocyte counts in clinically well children. Information or misinformation?

To determine whether the total and differential leukocyte count is of value as a case-finding test, we applied the evaluation criteria developed by the US Preventive Services Task Force. The criteria comprise review of the current burden of suffering of the disease to be prevented, the attributes of the intervention to be used, and the quality of the evidence available. A literature search revealed no evidence in the form of data from patients, so a chart review of all complete blood cell counts ordered during a 1-year period by one group of pediatricians was undertaken. At least one value outside of published normal ranges was found on 74.7% of the tests performed on clinically well children. No unsuspected illness was discovered as a result of an abnormal total and differential leukocyte count.

Adolescent↗
PubMedDate not supplied

Evidence syntheses in child health.

Evidence syntheses, also known as systematic reviews, differ from traditional reviews in that they are scientific evaluations of existing studies. Systematic reviews have explicit and reproducible methods and, as with any other scientific endeavor, the result of an evidence synthesis or systematic review can be critically appraised. Many sources for high-quality evidence syntheses now exist, with considerable support from government agencies to develop both the methods and the products of such reviews. Evidence syntheses can increase the efficiency and effectiveness of medical practice but face many hurdles, particularly in child health. These center around 4 areas: lack of high-quality primary studies, the difficulty of finding studies that do exist, the variability and usefulness of the outcome measures in child health, and problems with production and dissemination. Increasing attention to the need for high-quality child health research will help to ameliorate some of these issues, whereas solutions to others are under development or remain elusive.

Child↗