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Biomedical subjects

V A Mikhel'son

Publications and source records attributed to V A Mikhel'son.

At least 19 recordsLinked to original sources
PubMed1991

[Medium-weight molecules in the determination of the level of endogeneous intoxication in newborn babies].

Criteria for the diagnosis of the syndrome of endogenous intoxication were specified in neonates in a critical condition because of pathology of the early neonatal period. It has been established that early diagnosis of toxicosis is promoted by the determination of the pool of medium-weight molecules, the growth of which precedes the clinical picture manifestation. The totality of the indicators of the content of medium-weight molecules and the leukocytic index of intoxication determine the type of toxicosis (infectious, hypoxic, traumatic), predict its course and outcome, being an alternative in the choice of methods for body detoxifying.

Humans↗
PubMed1990

[The diagnostic and prognostic value of the indices of the colloid-osmotic state of the blood in children with the crush syndrome].

Eighteen infants with compression syndrome (CS) were managed with simultaneous evaluation of changes in the blood colloid osmotic status. The examination findings showed that plasma osmolality is an integral index of endogenous intoxication which objectively reflects the gravity of the general condition of patients and requires adequate correction. The osmolality gap was measured by the difference between the measured and calculated osmolalities; its stable two- or threefold increase was found to be the most unfavourable factor in the disease course and prognosis. It was found that control of osmotic homeostasis in infants with CS is essential to decide that extracorporeal blood clearance techniques be used and to elaborate effective infusion therapy programmes.

Adolescent↗