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Biomedical subjects

V A Lishchuk

Publications and source records attributed to V A Lishchuk.

At least 19 recordsLinked to original sources

[Current issues of medical informatics].

Due to the modern high standards of information technologies it is only natural to promote our medical care and to ensure a new quality of clinical services. Information technologies should be introduced into the medical field with due respect to clearly predetermined principles. Analyzed in the paper are the key reasons for a huge number of problems occurring in the sphere of medical informatics; optimal methods of medical-informatics introduction are defined.

Delivery of Health Care↗

[Effect of aortic clamping on hemodynamics at reconstruction of the thoracoabdominal aorta].

This paper describes an experience with monitoring and computerized follow up of the hemodynamic status in 60 patients at and right after reconstruction of the thoracoabdominal aorta. In addition to the routine control, measurements were made of the pressure in the large vessels and cavities of the heart, duration of each heart contraction and CI. The following parameters were computed automatically: the status of the ventricles for each heart contraction, resistance of the greater end pulmonary circulation, elasticity of the arterial, venous, pulmonary arterial and pulmonary venous reservoirs, also for each cardiac cycle. At the generally accepted monitoring the hemodynamic responses to the surgeon's manipulations on the aorta appear smoothed or are not visualized at all. The control of each heart contraction reveals the responses to application of the clamp and its removal from the aorta, with their hemodynamic significance being not questionable. Aortic clamping and clamp removal from the aorta are associated with the generalized response of the regulatory systems of the body. The slow and thoroughly controlled aortic clamping and graded, controlled blood flow restoration due to clamp removal as well as the use of sodium nitroprusside (trimetafan or isofluran are preferable) allow to avoid an abrupt stroke load of the left ventricle of the heart and, respectively, the generalized response of the regulatory systems of the body.

Aortic Aneurysm, Abdominal↗

[Acute disorders of the blood circulation and cardiac insufficiency following open heart surgery].

General theoretical aspects (classification of circulatory disorders and heart failure) and results of research into specific subdivisions of cardiovascular and respiratory system pathology in cardiac surgical patients are discussed. The material is aggregated by the applied clinico-mathematical approach that has been developed and introduced into clinical practice in the recent 15 years at the Bakulev Institute of Cardiovascular Surgery. The extension of the clinico-mathematical approach onto the intraoperative control and analysis of the patients' status, assessment of the anaesthetic administration and cardioplegic protection is first overviewed.

Acute Disease↗

[Changes in left-ventricular contractility and diastolic rigidity and the dynamics of various indicators of blood circulation in patients after aortic valve prosthesis].

The relationship between the stroke output and parameters relating to left-ventricular contraction and relaxation was examined within the early hours after the implantation of prosthetic aortic valve. Quantitative analysis demonstrated a close correlation between left-ventricular performance and diastolic regidity. Left-ventricular diastolic regidity is shown to make a more important contribution than contractility to the formation of stroke output. For this reasons, a therapy aiming only to improve myocardial contractility in patients after prosthetic aortic valve implantation failed to effectively improve their clinical condition.

Adolescent↗

[Role of computer technology and mathematical modelling in the treatment of patients after operations on the heart].

On the basis of ten-year experience in theoretical studies and experimental tests mathematical models of hemodynamics were built for the follow-up of parameters of the cardiovascular system which cannot be determined by means of any other modern methods. Three years of clinical studies of the Hewlett-Pachard monitoring computer system and its modification helped to elaborate the mathematical backing, a bank of mathematical models, original automatic programs for measuring the cardiac index, the index of myocardial viability, etc. The automatic system provides for an individual approach in assessing the patient's condition in actual time and for control of the treatment.

Cardiac Surgical Procedures↗