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Biomedical subjects

V A Kovalev

Publications and source records attributed to V A Kovalev.

At least 19 recordsLinked to original sources

[Complications after angioplasty and stenting of coronary arteries in ischemic heart disease patients].

The authors have made an analysis of most frequent complications of angioplasty and stenting of coronary arteries in 1900 patients with various forms of ischemic heart disease. The mechanisms, pathomorphology, angiographic and clinical manifestations of such complications as dissection of the coronary artery intima, acute occlusion of the coronary artery, "no-reflow" syndrome, perforation and rupture of the coronary artery, acute thrombosis in the stent area and other complications are considered in detail. Special medical strategy, both therapeutic and surgical, is proposed for each case. The authors propose a number of prophylactic measures allowing to avoid the complications described or to minimize them. Intraoperative lethality in this group of patients was 0.5% (10 patients), during the first week after endovascular intervention 26 patients died (1.4%).

Adult↗

Three-dimensional texture analysis of MRI brain datasets.

A method is proposed for three-dimensional (3-D) texture analysis of magnetic resonance imaging brain datasets. It is based on extended, multisort co-occurrence matrices that employ intensity, gradient and anisotropy image features in a uniform way. Basic properties of matrices as well as their sensitivity and dependence on spatial image scaling are evaluated. The ability of the suggested 3-D texture descriptors is demonstrated on nontrivial classification tasks for pathologic findings in brain datasets.

Brain↗

[Use of absorbable polymers for plastic repair of postoperative ventral hernias].

In surgical clinic of Vladivostok State Medical University 48 patients were operated for postoperative ventral hernias with use of absorbable polymers. In group 1 (42 patients) the explant "Carbonicus-I" was used (period of absorption-2 years). 6 patients of group 2 underwent plastic repair with suture-glue duplication of aponeurosis of abdominal white line. The analysis of the results demonstrated that explants "Carbonicus-I" and tissue glue "MK-7M" can be used for plasty of hernial ring on anterior abdominal wall in large ventral hernias. Polymers with long period of absorption (over 2 years) form dense scar which prevents recurrence of hernia. At the same time polymers with short period of absorption (4-6 months) reduce possibility of early reaction of explant rejection.

Absorption↗

[The surgical treatment of aneurysms of the abdominal aorta].

Based on an experience with treatment of 107 patients with aneurysms of the abdominal aorta subjected to planned or urgent operations the authors discuss the problems of the clinical course, diagnosis, indications for operative treatment, the technique of operative interventions and their results. In planned operations lethality was 4.1%, in ruptures of the aneurysm-64.2%. One year after the operations 90% of the patients were practically healthy, 5 years later they were 70%.

Aged↗

[Hemosorption with the use of porcine spleen in the treatment of purulent-septic diseases in children].

In 14 children with purulent septic diseases, the method of biohemosorption with the use of a porcine spleen was used. In 13 children, the treatment was effective. One child with bilateral uretherohydronephrosis, pyonephrosis, urosepsis, signs of aggravating polyorganic failure died. The data obtained are indicative of the expediency to use biohemosorption for treatment of children with purulent septic diseases.

Animals↗

[Surgical treatment of ischemic heart disease using internal thoracic artery and partial ileal bypass].

The authors recommend complex two-stage treatment of ischemic heart disease, including a reconstructive operation on the coronary arteries and an operation for correcting the disturbed plasma lipid spectrum (partial ileal bypass). The results of operative treatment of 150 patients with the use of the internal thoracic artery were studied. The authors emphasize the advantages of this operation over one using an autovein graft. Complex operative treatment was conducted in the clinic in 60 patients with a good clinical effect. The authors also recommend operation for partial ileal bypass as an independent intervention in dyslipoproteinemia and diffuse affection of the coronary arteries.

Adult↗

[Computer analysis of the contours of the large intestine for the purpose of disease diagnosis].

The authors put forward a new method of structural analysis of images, based on an automatic search for regularities of signs of colonic diseases in the shape of contours of colonic segments. The regularities obtained were used as diagnostic signs. The results of analysis of the shape of contours of the 1st (cecum and the ascending colon) segment and the 5th (the rectum) segment in 83 patients. The results of CT diagnosis coincided with verified clinical conclusions.

Adult↗

[Awl conductor].

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Humans↗

[Surgical treatment of chronic ischemic heart disease].

The authors suggest a new complex approach to the surgical treatment of ischemic heart disease. Operation of coronary shunting for the restoration of the coronary blood flow, operation of partial ileoshunting for correction of hyperlipoproteinemia, plexotomy for removal of the vasospastic component. The sequence of the operations may vary, each one can also be undertaken independently. The operations were conducted on 315 patients. The follow-up period is up to 8 years. Patency of the mammary-coronary shunts was 93.5%, of autologous veins shunt--65%. Disappearance of the signs of coronary spasm++ and stable normalization of the lipid spectrum are noted.

Adult↗