[Cancer: the history of its study, its epidemiology and the problems].
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Biomedical subjects
Publications and source records attributed to V A Kazakov.
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The study was concerned with analysis of the data on 342 patients with lung cancer aged more than 70 years, 170 of whom had undergone surgery (peripheral cancer--117, central--53). Considering the poor functional status of the patients and their low compensatory potential, mostly organ-saving procedures (80.4%) (lobe-, bilobectomy, segmentectomy or wedge pneumonectomy) were used. Postoperative, largely bronchopulmonary and cardiovascular, complications developed in 37.6%. Postoperative lethality rate was 14.7%: after partial resection of the lung--13.5%, pneumonectomy--29.6%.
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Lung cancer morbidity in Moscow in recent years is discussed. Two-thirds of the patients were 60 years of age or older. Lung cancer operability in Moscow has remained relatively stable accounting for 10-15%. The age distribution of the said parameter was as follows: patients under 60 years--30-32%; 60-69 years--12-14% and those over 70--4-5%. Results can be better if more middle-aged and elderly patients are operated on. The authors' clinical data on 842 surgical cases of lung cancer (males and females of varying age) are analysed.
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Among 5,400 male patients with lung cancer examined at Oncological Dispensaries of Moscow and Khabarovsk in 1967-1982, 37 men (0.7%) had never smoked. The latter group was characterized by prevalent incidence of glandular form of cancer and a relatively high percentage of old and middle-aged patients. No difference in the localization, clinical picture, operability and resectability of tumor was established between male smokers with lung cancer and non-smokers.
The data suggest that none of the materials produced in the USSR or imported, did fully reproduce the microrelief of the surface of metal standard. This is accounted for by the processes taking shape on the surfaces of elastomeric compositions upon their vulcanization.
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From analysis of the position and width of the diffuse maximum from X-ray scattering on hydrocarbon chains of phospholipid molecules, the average distance between neighbour chains in a bilayer and the values of interaction (correlation) radia were estimated. Comparison with the results of other methods applied shows that the cluster model of molecule packing in lipid bilayers explains the experimental data in the best way. The minimal dimensions of the clusters, average areas per molecule and approximate fraction of molecules in the clusters were estimated.