[New analogs of NAD containing a fluorescent pyridine fragment].
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Biomedical subjects
Publications and source records attributed to V A Iakovlev.
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The following were studied in 24 healthy men aged from 20 to 40 years: circadian rhythm of catecholamines and their precursors production, 17-ketosteroids, 17-oxycorticosteroids, variational pulsometry indices, arterial pressure parameters, resilient-viscous properties of large arterial vessels and arterioles, indices characterizing the mechanical activity of the myocardium. Comparison of the results obtained indicated that, although there existed no complete correlation between these indices, there proved to be a nocturnal tendency to reduction of noradrenaline and dopamine production, to reduction of 17-ketosteroids and 17-oxycorticosteroids, along with rarefaction of cardiac contractions, increased variation in the rhythm, and diminution of arterial pressure and cardiac output parameters. Reverse changes were noted during the day-time.
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