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Biomedical subjects

V A Degtiarev

Publications and source records attributed to V A Degtiarev.

At least 19 recordsLinked to original sources

[Contrast media: present status and future of their production and use].

Analysis of the problems involving the design and application of Soviet-made radiocontrast agents showed that the synthesis of such drugs as Iodamid, Triombrast, Etiotrast, Bilimin, and Bilignost in this country made it possible to eliminate the arrears in this field. Together with the elaboration of topics concerning the pharmacokinetics and adverse effects of the above contrast agents, this helped to create a sound scientific base for further work on the unsolved problems, primarily, (1) to synthesize Soviet non-ionogenic radiocontrast agents; (2) to prepare and introduce Soviet ultrasonographic contrast agents into practice; (3) to prepare and introduce magnetic resonance contrast ones into practice; and (4) to introduce unique radiocontrast agents such as triombrast as oil emulsion, oleoferrotrast, fine-dispersion barium sulphate, and chromoetiotrast into clinical practice and to set up their production.

Contrast Media↗

[Color decoding of roentgenograms and scintigrams of malignant lung neoplasms].

The authors have shown that the color decoding of x-ray-radioisotope information on 50 lung cancer patients (150 radiograms and 80 scannograms) raised the diagnostic efficacy. It opens up opportunities for the objective quantitative processing of results by performing histographic analysis of similar optical density zones. These data are impossible to obtain by using common methods of visual and roentgenogrammetric analysis. TV decoders of UAR-1 type are recommended for clinical practice.

Color↗

[Possibilities of measuring the dynamics of the stroke volume according to the data of ultrasonic Doppler-cardiography].

The possibility of determining the relative changes in the stroke volume of the left ventricle on the basis of ultrasonic Doppler-cardiography was studied in animal experiments and in tests with volunteers. The dynamic measurements of the cardiac output by means of ultrasonic Doppler-cardiography were performed on the basis of recording the amplitude of excursions of the posterior wall of the ventricle during the ejection phase by way of integrating the Doppler frequencies in the 150--800 cycles range. Simultaneously the dynamics of the cardiac output was studied electromagnetically (in animal experiments) and rheographically (in volunteers). The results of both the methods correlated closely: the reciprocal correlation coefficient in animal experiments comprised r=0.89 (p less than 0.001), in volunteers r=0.78 (p less than 0.001). The authors concluded that ultrasonic Doppler-cardiography can be used for measuring the relative changes in the stroke volume.

Adult↗