Biomedical subjects

Ugo H Buzzi

Publications and source records attributed to Ugo H Buzzi.

4 recordsLinked to original sources

PubMed2004

The effect of anterior cruciate ligament reconstruction on lower extremity relative phase dynamics during walking and running.

The purpose of this investigation was to use relative phase dynamics to evaluate gait in individuals with a reconstructed anterior cruciate ligament (ACL) during walking and running. Relative phase dynamics can describe the coordination strategies between the interacting segments at the lower extremity. Ten subjects who had undergone ACL reconstruction using the central third of their patellar tendon and ten healthy controls walked and ran on a treadmill at a self-selected pace. Relative phase dynamics were calculated for the foot-shank and shank-thigh coordinative relationships. Statistical differences between the groups were noted for the foot-shank relationship (p < 0.05) during both walking and running and for the shank-thigh relationship (p < 0.05) during walking. Our results indicate that current ACL reconstructive techniques may result in altered relative phase dynamics. These changes in relative phase dynamics could be related to a loss of sensory information about joint position and velocity that is typically provided by the intact ACL. Additionally, relative phase adaptations could be a learned response from the early stages of postsurgical rehabilitation. Relative phase dynamics provide quantitative information about the dynamic status of the ACL-reconstructed knee that cannot be gained from the conventional time-series evaluation of gait analysis data. Relative phase dynamics measures should supplement the conventional gait analysis measures that are used today for the clinical evaluation of the functional dynamic stability of the reconstructed knee. The examination of relative phase dynamics could be clinically important for the quantification of new ACL surgical interventions and of patient performance at various stages of rehabilitation. Further research should incorporate relative phase dynamics to understand the influence of ACL reconstruction on coordination and functional patient outcomes.

Adult↗

PubMed2004

Modeling dynamic resource utilization in populations with unique constraints: preadolescents with and without Down syndrome.

In this study we used a damped inverted pendulum and spring with an escapement function model to compare the global levels of stiffness and forcing used by 12 preadolescents with Down syndrome (DS) and 12 with typical development (TD). Participants walked overground at their self-selected speed and on a treadmill at speeds slower and faster than overground. Children with DS, who are characterized as hypotonic with reduced capacity for producing muscle force, exhibited significantly higher levels of stiffness and forcing (angular impulse) when walking on the treadmill and higher forcing but not stiffness overground, than children with TD. Both groups adapted to imposed speed increases similarly by increasing their global stiffness and angular impulse. We propose children with DS increased stiffness in order to overcome their hypotonia and joint laxity, thus, optimizing on stability, rather than metabolic efficiency. Higher angular impulse values for children with DS may reflect higher energy cost associated with increasing stiffness and their inherent biomechanical and physiological characteristics that reduce efficiency. We conclude that the inverted pendulum and spring with escapement function model is a useful tool for uncovering solutions to movement problems-solutions that reflect the dynamic resources of the individual and ones that are discovered, rather than prescribed.

Child↗

PubMed2004

Dynamic stability of gait cycles as a function of speed and system constraints.

The purpose of this study was to examine the dynamic stability of two groups of children with different dynamic resources in changing contexts. The stability of the lower extremity segments of preadolescent children (8-10 years old) with and without Down syndrome (DS) was evaluated as children walked on a motorized treadmill at varying speeds. Tools from nonlinear dynamics, maximum Lyapunov exponent, and approximate entropy were used to assess the behavioral stability of segmental angular displacements of the thigh, shank, and foot. Our results suggest that children with DS show decreased dynamic stability during walking in all segments and that this might be a consequence of inherently different subsystem constraints between these groups. Differences between groups also varied, though not uniformly, with speed, suggesting that inherent differences could further constrain the behavioral response to changing task demands.

Anthropometry↗

PubMed2003

Nonlinear dynamics indicates aging affects variability during gait.

OBJECTIVE: To investigate the nature of variability present in time series generated from gait parameters of two different age groups via a nonlinear analysis. DESIGN: Measures of nonlinear dynamics were used to compare kinematic parameters between elderly and young females. BACKGROUND: Aging may lead to changes in motor variability during walking, which may explain the large incidence of falls in the elderly. METHODS: Twenty females, 10 younger (20-37 yr) and 10 older (71-79 yr) walked on a treadmill for 30 consecutive gait cycles. Time series from selected kinematic parameters of the right lower extremity were analyzed using nonlinear dynamics. The largest Lyapunov exponent and the correlation dimension of all time series, and the largest Lyapunov exponent of the original time series surrogated were calculated. Standard deviations and coefficient of variations were also calculated for selected discrete points from each gait cycle. Independent t-tests were used for statistical comparisons. RESULTS: The Lyapunov exponents were found to be significantly different from their surrogate counterparts. This indicates that the fluctuations observed in the time series may reflect deterministic processes by the neuromuscular system. The elderly exhibited significantly larger Lyapunov exponents and correlation dimensions for all parameters evaluated indicating local instability. The linear measures indicated that the elderly demonstrated significantly higher variability. CONCLUSIONS: The nonlinear analysis revealed that fluctuations in the time series of certain gait parameters are not random but display a deterministic behavior. This behavior may degrade with physiologic aging resulting in local instability. RELEVANCE: Elderly show increased local instability or inability to compensate to the natural stride-to-stride variations present during locomotion. We hypothesized that this may be the one of the reasons for the increases in falling due to aging. Future efforts should attempt to evaluate this hypothesis by making comparisons to pathological subjects (i.e. elderly fallers), and examine the sensitivity and specificity of the nonlinear methods used in this study to aid clinical assessment.

Adult↗