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Biomedical subjects

U Welander

Publications and source records attributed to U Welander.

At least 19 recordsLinked to original sources

Orthodontic application of color image addition to visualize differences between sequential radiographs.

A new technique was developed making it possible to visualize changes that take place after premolar transplantation. Three sequential radiographs from a series of standardized control examinations were digitized and registered to the first radiograph in the series using subtraction technique. The digitized radiographs were then transformed into monochromatic images: red, blue, and green. After correction of gray level and contrast, the three radiographs were superimposed. All details that were common in the radiographs were then displayed in black-and-white. Details that were different appeared in color. Red and blue combines into magenta, blue and green into cyan, and green and red into yellow. A procedure was developed to create color-coded radiographs according to the above. The procedure was applied to cases that had been treated by premolar transplantation. The color coding offers the possibility to identify any radiographic changes that take place over time, eg, growth, apposition or resorption of bone, and progression or regression of pathological processes.

Bicuspid

Comparison of observer reliability in assessing alveolar bone changes from color-coded with subtraction radiographs.

OBJECTIVES: To assess intra- and interobserver agreement on marginal changes in periodontal bone from color-coded compared with subtraction radiographs. METHODS: Sequential radiographs from patients undergoing periodontal treatment were acquired using direct digital intra-oral radiography. Fifty-one pairs of color-coded and subtraction radiographs were produced and evaluated twice by six dentists for changes in marginal bone. Intra- and interobserver agreement were calculated. RESULTS: Intra-observer agreement was significantly higher for the color-coded radiographs (P < 0.05). Interobserver agreement was significantly higher for color-coded radiographs at the second (P < 0.001) but not the first (P = 0.34) evaluation. CONCLUSIONS: Color coding of radiographic differences by means of image addition may be a feasible alternative to the subtraction technique for evaluating periodontal bone changes.

Alveolar Bone Loss

A three-dimensional photographic method for documentation and measurement of dental conditions.

A 3-D photographic technique was developed for the registration of bite conditions. This technique may replace plaster models for archiving purposes. To achieve this, photographic equipment and computer programs should be user friendly, not too expensive, and allow measurements that satisfy scientific demands. This purpose was fulfilled by combining the following elements: a photographic unit with standardized conditions for 3-D photography and a reference object with known coordinates where bite impressions or models are placed during photography. To reconstruct 3-D coordinates from photographs these are placed on a digitizer connected to a computer programmed for reconstructing 3-D coordinates from the digitized 2-D data. The accuracy of the 3-D reconstruction of coordinates, x, y, z, was tested by means of 3-D photographs of a test object with reference points having a precision of +/- 0.5 micron. The mean error for distances of 5 mm and 15 mm varied between -0.17 mm and +0.15 mm. Measurements of 45 degrees and 90 degrees angles had an accuracy that varied from -0.5 degree to +0.9 degree and from -1.2 degrees to +1.5 degrees respectively. An angle between lines and a plane of 54.7 degrees displayed a mean error of +/- 1.6 degrees. The test of the accuracy of the 3-D photographic technique for calculating distances and angles demonstrated that it fulfills demands for scientific applications on clinical material.

Calibration

The perceptibility curve test applied to direct digital dental radiography.

OBJECTIVE: To compare the effect of an additional scintillator layer on the psychophysical properties of a CCD detector for digital dental radiography. METHODS: Radiographs of a test object containing ten holes of increasing depth were obtained throughout the exposure range of two CCD detectors at 70 and 90 kVp. One was the original detector for the Sens-A-Ray system (Regam Medical Systems, Sundsvall, Sweden) and the other the same detector covered by a scintillator layer. Ten viewers evaluated the radiographs for the number of perceptible holes. From these data and the dose response functions for the two detectors, the minimum perceptible exposure difference was found. The reciprocal values of this parameter were plotted against the logarithm of exposure to create Perceptibility Curves (PCs). RESULTS: The four PCs had essentially the same shape and height. There was a shift to lower exposures in the PCs for the detector covered by a scintillator. CONCLUSIONS: The two detectors have essentially the same psychophysical properties. Since the detector covered by a scintillator layer is more sensitive, it should be preferred for clinical practice since the dose to the patient is reduced.

Absorptiometry, Photon

A sensitometric comparison of four dental X-ray films and their diagnostic accuracy.

OBJECTIVES: To compare the sensitometric properties and accuracy in the diagnosis of approximal caries of two E-speed (Ektaspeed Plus and EV 57) and two D-speed (Ultra-speed and DV 57) films. METHODS: Speed and contrast for the four films were determined following 30 exposures for each film. Base plus fog density was measured on unexposed films and the increase was studied over a 18-month period. Seventy-five extracted premolars with known pathology were radiographed under standardized conditions and the radiographs assessed by nine observers for approximal caries. Receiver Operating Characteristic (ROC) curve technique was used to analyse the diagnostic accuracy. RESULTS: The sensitometric analysis showed that the Ektaspeed Plus film had the highest speed of the four films. At a density of 1.0 it was 2.28 times faster than Ultra-speed. The contrast of Ektaspeed Plus was comparable with that of the other films and base plus fog density plateaued at 0.4 ten months before expiry date. There were no statistically significant differences in diagnostic accuracy for white spot lesions between the four films. For cavitations there was a significant difference between EV 57 and DV 57 and Ektaspeed Plus (P = 0.005) but not between Ultra-speed and Ektaspeed Plus nor between Ultra-speed and EV 57 and DV 57. CONCLUSION: Ektaspeed Plus film is comparable with D-speed and a conventional E-speed film. Since it is at present the fastest available dental film it should be recommended for general dental practice.

Analysis of Variance

Absolute measures of image quality for the Sens-A-Ray direct digital intraoral radiography system.

To study the noise characteristics of the Sens-A-Ray (Regam Medical Systems AB, Sundsvall, Sweden) system, 20 radiographs were obtained at each of three different exposure levels at 70 and 90 kVp with a homogeneous x-ray field. Exposures were measured with an ionization chamber. Noise power spectra were calculated over three areas within each radiograph, and ensemble averages were subsequently found from 60 data files at each exposure level. Noise equivalent quanta were calculated with the noise power spectra and modulation transfer function data from previous studies. Finally, the detective quantum efficiency was calculated by dividing the noise equivalent quanta by the estimated incident photon fluence at the different exposures. The system has a maximum detective quantum efficiency of approximately 0.030 at 70 kVp and 0.025 at 90 kVp. A broad maximum exists at approximately 2 cycles/mm, indicating that the signal-to-noise ratio is most favorable at this spatial frequency.

Algorithms

Computerized measurements of the lower third molar related to chronologic age in young adults.

Chronologic age is an utmost important birth record in many industrialized Western countries. When the date of birth is unknown, there is a demand for establishing the chronologic age. Dental methods for age estimations are considered more reliable than most other methods by the majority of researchers and are among the most commonly used means to determine age. Traditionally, these methods have most often been based on subjectively estimated, radiographic stages of tooth development. In the present study metric measurements of the length of the forming root have been used and are compared with one standard method. The formed part of the root of the lower third molar as seen in a panoramic radiograph was digitized. Data were directly stored in a computer for subsequent statistical analysis. The technique of collecting data with the aid of a computer had some statistical advantages. The precision of age estimations was, however, slightly inferior to the standard method.

Adolescent

Color coding of radiographic changes over time by means of image addition.

Differences between sequential radiographs may be displayed in color if the individual radiographs are transformed into monochromatic images and then added. Information in regions where the radiographs are identical is retained whereas differences are emphasized by the color coding that comes about in a quantitative manner from the gray level values in the sequence of radiographs. By using the three additive primary colors, red, blue, and green, two or three radiographs from a sequence may be added. Every possible state of a bone disease, progression, regression, or any combination, will produce a different and specific color code. Different development cycles are described, and the color coding that appears when color image addition is performed is analyzed. The color addition technique should constitute a useful substitute or alternative to subtraction.

Alveolar Bone Loss

Exposure parameters and their effects on diagnostic accuracy.

A new method for analyzing diagnostic accuracy is introduced. A diagnostic accuracy curve may be obtained by plotting receiver operating characteristic analysis data, P(A), as a function of exposure. By means of diagnostic accuracy curves the effects on diagnostic accuracy of tube potential, exposure, and size of carious lesions was studied. It was found that the effect of the tube potential on the accuracy of caries diagnosis is negligible. About 25% of the variation in diagnostic accuracy depends on the exposure and about 80% on lesion depth. With the lesion depth constant, about 75% of the variance in diagnostic accuracy depended on observer performance. The peak of a diagnostic accuracy curve indicates optimum performance. This is found at an exposure that gives a radiographic density of about 1 in enamel and dentin although the tolerable exposure increases with increased lesion depth.

Absorptiometry, Photon

A simple method for measuring MTF in direct digital intraoral radiography. Technical note.

Conventional methods for measuring the modulation transfer function require the exposure of a narrow slit or straight edge followed by computationally intense data analysis. An alternative method applicable to digital systems uses the standard deviation of gray levels within different frequency regions of a bar pattern. To verify that this method gave reliable results, measurements performed for two systems for intraoral radiography with the use of this method have been compared with modulation transfer function values calculated from Fourier transformations of line spread functions measured for the two systems. The almost identical results confirm the consistency of both sets of modulation transfer function measurements and demonstrate the utility of the bar pattern method for performing rapid measurements.

Fourier Analysis

Resolution as defined by line spread and modulation transfer functions for four digital intraoral radiographic systems.

Line spread functions for four commercially available systems for direct digital intraoral radiography were determined from images of a slit of negligible width. From the fitted line spread functions presampling modulation transfer functions were calculated. The four systems were the Sens-A-Ray (Regam Medical System AB, Sundsvall, Sweden), the VIXA/Visualix (Gendex, Chicago Ill.), the RVG (Trophy Radiologic, Paris, France), and the Flash Dent (Villa Sistemi Medicale srd, Buccinasco, Italy). Digital intraoral radiography is in a state of rapid development, and detectors as well as computer hardware and software are continually modified and improved resulting in successively changing system parameters. As this occurs the present work provides a method that may be used to determine comparable data on future systems.

Electronics, Medical

Age estimation with the aid of tooth development: a new method based on objective measurements.

The common methods of age determination with the aid of teeth have been criticized because they rely on subjective estimations of tooth development, as seen in radiographs, and subsequent comparisons with pictures and descriptions in compiled dental charts. The distribution around an estimated age with these methods is usually more than +/- 2 yr between the 10th and 90th percentiles. In an attempt to avoid subjective estimations, objective measurements of developing teeth were correlated with subjects' chronologic ages. The structures measured were crown height, apex width, and root length. With the aid of a multiple regression model, a linear relationship between some of these distances and age was shown. The distances which were best correlated with age differed according to sex and age. This method has a 95% C.I. of about +/- 2 yr around an estimated age. It therefore seems to be more accurate than the earlier methods. Thus, the individual variation in tooth development is of the same order of magnitude, and a better estimation can therefore not be done in children 6-14 yr of age.

Adolescent

Radiographic interproximal angulations: implications for rotational panoramic radiography.

Axial radiographs were taken on 160 subjects at the screening clinic of the Dental School, University of Texas Health Science Center at San Antonio. Intermeatal and midsagittal lines, together with coordinate axes and polynomial curves that represent the average dental arch form, were overlaid on each radiograph. Coordinate references for interproximal tangents at 3154 contacts along the average dental arch form were digitized and angulations between the arch form and midsagittal plane calculated. Interproximal angulations at the average arch form were found to vary greatly but the average fluctuated around 90 degrees over the length of the arch. Optimal beam angulations were shown to be considerably different from central ray angulations of current panoramic machines, and although most machines demonstrated favorable interproximal beam angulation in the anterior region, discrepancy in the premolar region ranged from 15 degrees to over 40 degrees. Overall the OrthOralix SD (Gendex Dental Systems, S.r.l., Monza, Italy) orthogonal projection and PM 2002 CC (Planmeca Inc. Helsinki, Finland) deviate least from optimal interproximal angulation over most of the dental arch. However, the Planmeca gives a better angulation in the canine/premolar region, whereas the OP5/10 (Palomex Instrumentarium Corp., Helsinki, Finland) is comparable with the OrthOralix SD in the molar region.

Analysis of Variance

Basic technical properties of a system for direct acquisition of digital intraoral radiographs.

The Sens-A-Ray system for direct digital intraoral radiography may be used with any computer compatible with an IBM PC/AT. The system relies on a charge-coupled device designed for direct conversion of x-ray energy to an electronic signal. It is the first such device for direct acquisition of radiographs. Technical properties of charge-coupled device detectors when exposed to radiation energies in the range of x-rays used in dental radiography have been studied. Even in the absence of light or x-radiation there is a spontaneous generation of charge within a charge-coupled device detector that gives rise to a background signal, a dark current. It was found that the dark current is a linear function of exposure time. The dose response of the charge-coupled device detector was determined at nominal kilovoltages that range from 50 to 90 kVp. The dose response was shown to be a linear function of exposure. The functions for all kVp settings were practically identical. The charge-coupled device detector is more sensitive to x-radiation than conventional dental films and, consequently, its exposure range is more narrow. The signal-to-noise ratio was calculated from the digital radiographs used for the dose response test. The ratio is above 10 for exposures higher than about 2 microC/kg. The line spread function was determined from test radiographs of a 10 microns wide slit in a test object of 1.5 mm thick tantalum. After curve fitting, the line spread function could be expressed as the sum of a Gaussian and an exponential function. Presampling modulation transfer functions valid at the detector plane and at an object plane were calculated from fitted data on the line spread function. It is concluded that the Sens-A-Ray system has such technical properties that it may replace conventional film-based systems.

Computer Graphics

Dimensional reproduction in direct digital rotational panoramic radiography.

A linear x-ray detector array can be used to perform rotational panoramic radiography provided a technique for data acquisition is used that emulates the dimensional reproduction of a conventional rotational panoramic radiographic system. This may be accomplished with the use of a variable integration time throughout the excursion. The required interval depends upon the scanning geometry, the selected image plane, and the size of pixels used in the digital image. In a prototype device developed around an Orthopantomograph Model OP10 with 0.225 mm square pixels, the integration times range from about 8 milliseconds to 28 milliseconds. An experimental test was performed by radiographing a number of steel spheres positioned at different object depths. Within the limits of experimental error, there was satisfactory agreement between the measured and theoretical magnification.

Humans

Layer thickness in panoramic radiography as defined by different noise-equivalent passbands.

The layer thickness in rotational panoramic radiography is presented with the use of the concept of the noise-equivalent passband. Conventionally, the layer thickness has been calculated only from one-dimensional data in the horizontal or rotational dimension of panoramic radiography. In the present study, results from calculations using both one- and two-dimensional data are presented. When the vertical dimension is included in the calculations, the layer is wider than when calculated from data in the horizontal dimension only. It is pointed out that the wider layer that follows from the introduction of the vertical dimension may be the most reliable measure of layer thickness in panoramic radiography.

Bone Density

Preliminary evaluation of a digital system for rotational panoramic radiography.

A prototype system for direct digital panoramic radiography has been evaluated with respect to density, contrast, magnification, distortion, resolution, and overall image quality. Density and contrast depend on detector calibration and may be modified by the display system or by digital processing of the captured image. Variation of magnification in the horizontal and vertical dimensions gives rise to distortion phenomena that are identical to those encountered in film-based systems. Resolution in the vertical dimension is determined by the pitch of the detector elements. In the horizontal dimension, resolution is limited by the effective width of the detector elements. To evaluate the clinical acceptability of the images, radiologists and general practice residents were asked to assess the perceptibility of important radiographic landmarks in film-based and digital images of both a radiographic phantom and a patient. The digital system performed on a par with film in the representation of normal morphologic structures of the clinical human subject whereas more differences were apparent in the phantom images. The general practice residents consistently rated the digital images higher than their radiologist counterparts did. No consistent trends were found to indicate any inherent deficiencies of the digital system in the depiction of any one area. The results indicate the promise of direct digital acquisition as a method of panoramic imaging.

Evaluation Studies as Topic