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Biomedical subjects

U Stosiek

Publications and source records attributed to U Stosiek.

32 records · Page 2Linked to original sources
PubMed1976

[Changes in blood coagulation and thrombocyte aggregation during extended inhibition of labor (author's transl)].

The influence of extended tocolysis with Partusisten on blood coagulation was examined in 30 patients at various times during pregnancy. A rapid and statistically significant reduction of thrombocyte aggregation was found in all examined parameters. The effect was independent of the method of administering the medicine and continued during the whole period of time examined. Values, with which an increased tendency toward hemorrhage could be expected, did not occur. The values possibly reflect an increased disaggregation of the thrombocytes. The decreased whole blood viscosity with an unchanged hematocrit could also improve placental perfusion and, thereby, the nourishment of the fetus. All examined parameters of plasmic coagulation remained normal. No signs of a hypercoagulability or an increased fibrinolysis were present.

Blood Coagulation↗
PubMed1975

[The effect of radiotherapy on blood clotting and thrombocyteaggregation in patients with gynecological carcinomas (author's tranls)].

This is a study about changes in blood clotting and thrombocyteaggregation in 55 patients with gynecological carcinomas undergoing radiotherapy. The usual thromboembolism prophylaxis were supplemented by 10000 USP-U Heparine administered subcutaneously in 12-hour-intervals. After radiotherapy there was no change in blood clotting values, gross-thrombocyte count or in percentage of thrombocytes involved in aggregation. Aggregation velocity was significantly higher directly after radiotherapy compared to before, it reached normal values after 4 days. The increase was virtually independent of age, body weight or radio therapy dosage. The strangest increase with doubling of normal aggregation speed was found in primary insertions. Second- and third-time insertion showed only smaller increases. Subcutaneous application of Calciparin was simple and painless, in one case the medication had to be discontinued because of a bleeding in the pectoralis area. An increased bleeding tendency was not observed. Thromboembolic complications did not occur.

Adult↗
PubMed1975

[The influence of hydroxyethyl starch on blood clotting (author's transl)].

It has been shown in clinical experiments that blood coagulation was delayed by Dextran 60 and Hydroxyethylstarch (HAS). During the postoperative period up to the 2nd postoperative day the measured clotting factors were decreased within the physiological range. Platelet adhesiveness was mainly reduced in the group of Dextran 60 and in the male Hydroxyethylstarch group. A similar effect of haemodilution as seen by haematocrit and blood viscosity results was produced by Dextran 60 and Hydroxyethylstarch. In the electrolyte group the values obtained did not show any significant influence on blood coagulation apart from a light and temporary trend to hypercoagulation during the day of operation.

Adult↗