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Biomedical subjects

U Sharma

Publications and source records attributed to U Sharma.

At least 109 records · Page 6Linked to original sources
PubMed1971

Effectiveness of oral killed typhoid vaccine.

A controlled field trial of oral killed typhoid vaccine was carried out in Delhi, India in 1968-69. Altogether, 13 374 children below the age of 17 years were included in the study. Two comparable groups of children were given either placebo or vaccine. Each tablet of vaccine contained 100x10(9) killed Salmonella typhi, and 3 tablets of vaccine or placebo were administered to each child. The vaccinated subjects were followed up from 10 June 1968 to 31 August 1969. The effectiveness of the vaccine was measured by comparing the incidence of typhoid fever (based only on bacteriologically positive cases) in the two groups. It was found that the difference in incidence of the disease in the two groups was not statistically significant. The oral killed typhoid vaccine in the dosage schedule used in the present trial was found not to be effective against the disease.

Administration, Oral↗
PubMedDate not supplied

Standard curves for mid arm circumference and mid-arm/head circumference ratio in newborns.

One Thousand singleton neonates, between 28 and 44 weeks of estimated gestational age (EGA) were measured within 48 hours of their birth for upper mid-arm circumference (MAC), head circumference (HC) and birth weight (BW). Regression analysis was used to draw standard curves for MAC versus EGA and mid-arm circumference/head circumference ratio (MAC/HC) versus EGA. Correlation coefficients were 0.961 for MAC versus EGA and 0.889 for MAC/HC versus EGA (p less than 0.001). MAC, MAC/HC and HC were also highly correlated with birth weight (p less than 0.001). These standard curves make available a discriminating method for evaluation of intra-uterine growth and a non-invasive technique for following somatic protein status in growing preterm infants.

Anthropometry↗
PubMedDate not supplied

Poisoning in children: Indian scenario.

The retrospective data on childhood poisoning from eight regional hospitals in India has been reviewed. The demographic features and types of poisonings encountered have been compared. The analysis of the data indicated that pediatric poisonings constituted 0.23-3.3% of the total poisoning. The mortality ranged from 0.64-11.6% with highest being from Shimla. Accidental poisoning was common involving 50-90% of children below 5 years of age and males outnumbered the females. Suicidal poisoning was seen after 13 years of age and was due to drugs and household chemicals. One of the hospitals in Delhi recorded a very high incidence (66.6%) of drug poisoning in children. The drugs consumed belonged to phenothiazines, antiepileptics and antipyretics. Iron poisoning was seen in younger children. Kerosene was one of the causes of accidental poisoning at all hospitals except Shimla and rural Maharashtra were probably wood charcoal is widely used. Pesticide poisoning was more prevalent in Punjab and West Bengal whereas plant poisoning was very common in Shimla. Significant number of snake envenomation has been recorded from rural Maharashtra. Other less common accidental poisonings in children included alcohol, corrosives, heavy metals, rodenticides, detergents and disinfectants. Thus various regions in the country showed some variation in types and frequency of childhood poisoning which could be attributed to different geographical and socio-economic background.

Adolescent↗