Biomedical subjects

U Sehirli

Publications and source records attributed to U Sehirli.

8 recordsLinked to original sources

PubMed2001

Cerebellar connections to the dorsomedial and posterior nuclei of the hypothalamus in the rat.

The stimulation or ablation of cerebellar structures has produced a variety of visceral responses, indicating a cerebellar role in visceral functions. Studies using anterograde and retrograde tracing methods have revealed connections between the hypothalamus and cerebellar structures. The aim of this study is to investigate the cerebellar connections of the dorsomedial (DMH) and posterior hypothalamic nuclei using retrograde axonal transport of horseradish peroxidase (HRP). In the present study, micro-injection of HRP restricted within the borders of the DMH showed that the projections of this nucleus are not uniform throughout its extent. The posterior DMH receives projections from the cerebellum, whereas the anterior DMH does not. These projections were from the (greatest to least concentration) lateral (dentate), anterior interposed (emboliform), and medial (fastigial) cerebellar nuclei. In addition, both the anterior and posterior DMH receive projections from various areas of the brainstem which confirms earlier studies and provides detailed descriptions. This study also demonstrates the distribution of labelled neurons to cerebellar and brainstem nuclei following HRP injection into the posterior hypothalamic nucleus. It provides clear evidence for a direct cerebellar nuclei-posterior DMH and cerebellar nuclei-posterior hypothalamic nucleus connections. We suggest that the brainstem reticular nuclei and other connections, such as the solitary, trigeminal and vestibular nuclei, of both DMH and posterior hypothalamus may contribute to the indirect cerebellohypothalamic connections. These observations offer a new perspective on the question of how the cerebellum may influence autonomic activity.

Animals↗

PubMed2001

The afferent connections of the posterior hypothalamic nucleus in the rat using horseradish peroxidase.

The posterior hypothalamic nucleus has been implicated as an area controlling autonomic activity. The afferent input to the nucleus will provide evidence as to its role in autonomic function. In the present study, we aimed to identify the detailed anatomical projections to the posterior hypothalamic nucleus from cortical, subcortical and brainstem structures, using the horseradish peroxidase (HRP) retrograde axonal transport technique in the rat. Subsequent to the injection of HRP into the posterior hypothalamic nucleus, extensive cell labelling was observed bilaterally in various areas of the cerebral cortex including the cingulate, frontal, parietal and insular cortices. At subcortical levels, labelled cells were observed in the medial and lateral septal nuclei, the bed nucleus of stria terminalis, and various thalamic and amygdaloid nuclei. Also axons of the vertical and horizontal limbs of the diagonal band were labelled and labelled cells were localised at the CA1 and CA3 fields of the hippocampus and the dentate gyrus. The brainstem projections were from the medial, lateral and parasolitary nuclei, the intercalated nucleus of the medulla, the sensory nuclei of the trigeminal nerve, and various reticular, vestibular, raphe and central grey nuclei. The posterior hypothalamic nucleus also received projections from the lateral and medial cerebellar nuclei and from upper cervical spinal levels. The results are discussed in relation to the involvement of the posterior hypothalamic nucleus in autonomic function and allows a better understanding of how the brain controls visceral function.

Animals↗

PubMed1999

An unusual flexor hallucis longus muscle.

During the dissection of the posterior compartment of the left leg, an unusual flexor hallucis longus muscle of a fifty two years-old male cadaver was observed. On the medial side of the flexor hallucis longus, on its lower distal half, a prominent aponeurotic structure was observed. A small unusual muscle mass was attached to this aponeurotic structure. The muscular fibres of the unusual mass were arranged in form of bipennate muscle. It originated via a broad tendon from the muscular fibres of the tibialis posterior and the deep transverse fascia covering the same muscle. It inserted on the aponeurosis of the lower medial half of the flexor hallucis longus muscle. Having in mind the very different pathology in the region of the ankle and the foot, the significance of such a muscle mass could be of practical importance.

Cadaver↗

PubMed1998

An unusual variation of extensor digitorum brevis manus: a case report and literature review.

An unusual variation of the extensor digitorum brevis manus in a male cadaver is presented. The band-shaped muscle was located at the ulnar side of the hand between the fourth and fifth extensors. It originated from the deep carpal fascia and inserted to the extensor tendons of the fourth and fifth fingers with a tendon and a slip, respectively. The origin, insertion, and location of the muscle differ from those previously reported; with these anatomic features, the muscle variation cannot be placed into the current classifications. The phylogenetic and ontogenetic implications of the muscle are reviewed.

Cadaver↗

PubMed1998

A variation of coeliac trunk.

The anatomical variations of the coeliac trunk are due to developmental changes in the ventral splanchnic arteries. This report describes a case in which the left inferior phrenic artery and left gastric artery arose from the long coeliac trunk (4.3 cm.) via a common trunk. The arterial variations, like other anatomical variations, cannot be ignored during the operative procedures in abdomen. Therefore the different forms of variations concerning the coeliac trunk should be kept in mind during both surgical and non-surgical evaluations.

Aged↗

PubMed1997

Celiacomesenteric trunk.

The celiac trunk is the widest ventral branch of the abdominal aorta. The unusual embryological development of the ventral splanchnic arteries can lead to considerable variations. During the dissection of a 54-year-old male cadaver as a rare variation, a celiacomesenteric trunk was observed. The rare occurrence of this variation is stated to be 1%-2.7%. As in the other case, the celiac trunk and the superior mesenteric arteries arose from a common trunk at the level of L1. This case of celiacomesenteric trunk is described in detail, which can be of value in the operative procedures of the upper abdomen.

Celiac Artery↗

PubMed1996

An accessory mylohyoid muscle.

During dissection of the submandibular region of a forty year old male a unilateral left accessory mylohyoid muscle was revealed. This muscle was located between the left anterior belly of the digastric and left mylohyoid muscles. It arose from the left mylohyoid line of the mandible and was inserted into the lower portion of the mylohyoid raphe and hyoid bone. This unilateral accessory mylohyoid muscle is a rare anomaly, which is thought to contribute to the functional support of the floor of the mouth.

Adult↗

PubMed1996

The accessory tendon of the extensor indicis muscle.

The extensor indicis and the extensor pollicis longus muscles differentiates from the extensor digitorum profundus muscle. The extensor indicis muscle is an unstable muscle concerning its variations. Kosugi (1989) found the frequency of variations of this muscle to be 20% and described 18 different types of variations of this muscle. This study describes a rare case of the extensor indicis muscle. The extensor indicis muscle develops an accessory tendon in between the extensor indicis and extensor pollicis longus muscle. It passes under the extensor retinaculum. At the level of 2nd metacarpal bone, the accessory extensor indicis tendon is connected to the tendon of the extensor pollicis longus muscle by a intertendinous connection.

Cadaver↗