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Biomedical subjects

U S Nayak

Publications and source records attributed to U S Nayak.

At least 19 recordsLinked to original sources
PubMed2002

Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome.

In nephrotic syndrome, large amounts of plasma proteins are lost in urine, causing a decrease in the plasma oncotic pressure. This leads to enhanced hepatic synthesis of albumin and other proteins, including lipoproteins, causing a secondary hyperlipidemia. Essential fatty acids such as gamma-linolenic acid (GLA) can prevent accumulation of cholesterol in the body, and spirulina has an appreciable amount of GLA. In this study 23 patients (age 2 to 13 years) with nephrotic syndrome received either medication (group I) or medication plus 1 g/day Spirulina (group II). Height, weight, and serum levels of fasting blood sugar, triglycerides, total cholesterol (TC), and low- and high-density cholesterol fractions (LDL-C and HDL-C, respectively) were measured before and after the 2-month study period. Mean height and weight were normal compared with healthy, age-matched Indian children. Lipoprotein cholesterol levels were significantly increased at baseline. TC significantly decreased by 116.33 mg/dl, LDL-C by 94.14 mg/dl, and triglycerides by 67.72 mg/dl in group II; in control group I, these values fell by 69.87, 61.13, and 22.62 mg/dl, respectively. The LDL-C:HDL-C ratio also decreased significantly, by 1.66 in group II and 1.13 in group I. TC:HDL-C decreased by 1.96 in group II and 1.19 in group I. HDL-C:LDL-C also improved significantly in both the groups. It can be concluded that spray-dried Spirulina capsules, rich in antioxidants, GLA, amino acids, and fatty acids, helped reduce the increased levels of lipids in patients with hyperlipidemic nephrotic syndrome.

Adolescent↗
PubMed1999

Prevalence of lower urinary tract symptoms and self-reported diagnosed 'benign prostatic hyperplasia', and their effect on quality of life in a community-based survey of men in the UK.

OBJECTIVES: To assess the prevalence of lower urinary tract symptoms (LUTS) in a community-based population in the UK, to measure the impact of these symptoms on quality of life and health status in men with self-reported 'benign prostatic hyperplasia' ('BPH'), and to evaluate health-seeking behaviour in this population. SUBJECTS AND METHODS: A postal survey was distributed to an age-stratified random sample of 1500 men aged 50 years or older from throughout England, Scotland and Wales. The self-administered survey included: demographic questions; the EuroQoL (EQ-5D) instrument, consisting of a health-status index questionnaire and a visual analogue scale (VAS) on which participants rated their current health status; the International Prostate Symptom Score (IPSS) questionnaire; and a questionnaire assessing the participants' health-seeking behaviour and awareness of BPH. RESULTS: Responses to the survey were received from 1115 (74%) of the 1500 men. Overall, 41% (450/ 088) had an IPSS of > or =8, indicating moderate-to-severe LUTS, yet only 196 men (18%) reported that they had been diagnosed with 'BPH'. Both quality of life (as measured by the EQ-5D) and general health status (as measured by the VAS) decreased as urinary symptom severity increased, and the greater the severity, the more men who reported a problem with mobility, self-care, usual activity, pain/discomfort, and anxiety/depression (the five domains of the EQ-5D). The possibility of symptoms worsening appeared to be the key determinant in the respondents' decisions to consult a medical professional for their LUTS. Less than 11% of the respondents were aware of the availability of specific prescription drug therapies or surgical options for the treatment of 'BPH'. The most common first treatment strategy for those consulting for symptoms was watchful waiting (34%), followed by surgery (30%) and prescription drugs (21%). CONCLUSIONS: Moderate-to-severe LUTS were relatively common in this UK population of men over the age of 50, yet relatively few had been diagnosed with 'BPH'. As LUTS adversely affect quality of life, improved treatment options and increased public awareness of BPH and LUTS are needed to combat a problem facing the growing number of elderly men in the population.

Aged↗
PubMed1992

Effects of cervical collars on standing balance.

The effect of cervical collars on standing balance in two age groups was examined. Twenty healthy women aged 60 to 78 years and 20 healthy women aged 18 to 29 years stood on a Kistler force platform with and without a cervical collar. Total, lateral and anteroposterior sway velocity were measured in each of three positions; long-base stance and eyes open, wide-base stance and eyes open, and wide-base stance and eyes closed. Analysis of variance showed no significant difference (p < .05) between the collar and no collar conditions for any of the standing balance measures. Older women had significantly more sway velocity (p < .001) than younger women during long-base standing both with and without the collar. Also they showed significantly more sway velocity in both the total (p < .01) and the anteroposterior (AP) directions (p < .001) of wide-base standing. There were no significant lateral sway velocity differences (p < .05). With eyes closed, sway velocity was greater in all age groups. In the wide-based condition there were significant differences in sway velocity between AP (p < .001) and total and lateral (p < .01). These results indicate that a cervical collar does not disturb standing balance in healthy women in the age groups tested.

Adult↗
PubMed1989

The effect of visual deprivation and proprioceptive change on postural sway in healthy adults.

In 39 healthy active people aged 17 to 79 who had not fallen, anteroposterior sway during quiet standing increased slightly with age; there was no increase with age in lateral sway. Sway increased on deprivation of visual information and altered proprioception due to foot pressure sensory change in all age groups, and especially when both forms of sensation were altered concurrently; but the increase of sway on pressure sensory change was no greater in the older than in the younger subjects.

Adolescent↗
PubMed1988

Visual push: a sensitive measure of dynamic balance in man.

Forty-six subjects aged 17 to 79 years who had not fallen in the previous year were exposed to an illusory visual stimulus while they stood on a force platform, with or without the introduction of a polyurethane foam pad under their feet to reduce proprioception. The amplitude of sway obtained in this way was not correlated to age, but the sway path in the anteroposterior plane increased logarithmically with increase in age. The method proved to be more sensitive than similar measures obtained without the illusory visual stimulus.

Adolescent↗
PubMed1988

Balance function in elderly people who have and who have not fallen.

Balance function was measured by a "visual push" method in three groups of subjects aged 65 and over. These groups were comprised of 27 "recent fallers" who had fractured their wrists, 15 subjects who had fallen at least once in the previous year although not recently ("remote fallers"), and 20 subjects who had not fallen in the previous year ("nonfallers"). Subjects who had fallen recently or remotely had significantly more sway on illusory visual stimulation than subjects who had not fallen. The "visual push" test of balance may be capable of distinguishing between elderly people who are and who are not at enhanced risk of falling.

Accidental Falls↗
PubMed1987

Comparison of the Wright ataxiameter and the Kistler force platform in the measurement of sway.

A comparison has been made between two methods of measuring body sway during quiet standing. In the first method a Wright ataxiameter was used to measure the trunk movement in the anteroposterior direction; whilst in the second method a Kistler force platform was used to monitor the locus of the resultant ground reaction force. The good correlation between the two sets of data has resulted in a regression equation to convert one set into the equivalent other set. This equation should be useful while comparing the sway data from various research centres.

Adult↗
PubMed1987

Why do old people stoop?

Measurements of balance and of stooping were made in 38 healthy and active volunteers of various ages, and in 16 patients who had suffered falls and subsequent limitations of mobility. All subjects were able to stand unsupported for 30 seconds. Balance function as measured sensitively on a Kistler force plate showed a tendency to progressive impairment with increasing age. No difference was detected in balance between those who had fallen and between normal subjects of the same age. No relationship was observed between the measurements of stooping and age or the occurrence of a fall. Stooping does not occur as an adaptation to the minor degrees of balance impairment demonstrated in these subjects.

Accidental Falls↗
PubMed1987

Rapidly filling pleural effusion due to a subarachnoid-pleural fistula.

Only five cases of subarachnoid-pleural fistula in children have been reported previously. All had a history of trauma and associated neurologic deficit which gave clue to the diagnosis. The authors present a child who presented with a massive, rapidly filling, clear pleural effusion in whom there was no neurologic deficit. The history of an automobile accident in the past had almost been forgotten. A subarachnoid-pleural fistula was discovered on exploratory thoracotomy. The entity should be thought of, and actively investigated, in a child with a history of trauma and a pleural effusion of obscure etiology, even if there is no associated neurologic deficit.

Accidents, Traffic↗
PubMed1986

Balance in elderly patients: the "get-up and go" test.

The "get-up and go test" requires patients to stand up from a chair, walk a short distance, turn around, return, and sit down again. This test was conducted in 40 elderly patients with a range of balance function. Tests were recorded on video tapes, which were viewed by groups of observers from different medical backgrounds. Balance function was scored on a five-point scale. The same patients underwent laboratory tests of gait and balance. There was agreement among observers on the subjective scoring of the clinical test, and good correlation with laboratory tests. The get-up and go test proved to be a satisfactory clinical measure of balance in elderly people.

Accident Prevention↗
PubMed1985

Positional and optokinetic nystagmus in healthy old people.

Positional nystagmus and asymmetry of the optokinetic response were each found in four of 10 symptomless subjects aged 69 to 76 years who had normal balance function as demonstrated on the Kistler force platform. Positional nystagmus was also found in one of 10 healthy young subjects, none of whom had an abnormal optokinetic response. Abnormalities of these responses are therefore common in healthy old people and lack diagnostic specificity.

Adult↗