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Biomedical subjects

U Richter

Publications and source records attributed to U Richter.

At least 37 records · Page 2Linked to original sources

[Immune reactions of the conjunctiva and cornea following severe chemical burns of the outer eye].

Conjunctival and corneal tissue samples from nine patients with severe changes after acid and alkali burns were examined immunohistochemically. Epithelial HLA Class II antigen expression was present in three of five conjunctival samples, and all of the antigen markers examined in the conjunctival stroma could be stained. HLA Class II expression was demonstrated in four out of five corneal tissue samples. The results show that in Grade III or IV chemical burns, with the diverse changes of the external eye that they produce, immunological and possibly also autoimmune mechanisms can influence the clinical course.

Autoimmune Diseases↗

[A food-borne infection caused by Campylobacter jejuni serotype Lauwers 19].

Report on a outbreak due to contaminated food involving 556 schoolchildren who got their lunch from a school kitchen. The outbreak occurred abruptly without any secondary infectious. Examinations for Salmonellae, Shigellae, Enteritis-coli, Yersiniae and Rotaviruses were negative. However, Campylobacter jejuni were isolated from 105 specimens of faeces in Rostock. Sixty of these strains and another 2 that had been isolated at the same time but had no relation to the outbreak in Rostock, were further differentiated in Berlin-Buch. All of them proved to be Campylobacter jejuni biotype 2. Serotyping according to Lauwers revealed that 58 out of the 60 strains isolated belong to serotype 19. One of the two remaining strains could not be typed, the other was identified as serotype 1. One of the two cultivated strains that were not related to the outbreak in Rostock, was untypable, the other being of serotype 2. Therefore it can be assumed that the outbreak came from the same source of infection. Epidemiological investigations pointed to some food which had been served 6 days prior to the outbreak. The meal had consisted of white cabbage stew with beef. The kitchen supplies the cooked food to several institutions; 3 different dishes being prepared each day, referred to as dish, A, B and C. The institutions receiving dish A - which on November 1, 1985 was the above-mentioned white cabbage stew - actually included several classes of a school as well as a kindergarten. On that particular day however the kindergarten had not been supplied with dish A but, as an exception, with dish B.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Threshold of hearing by bone conduction. A contribution to international standardization.

Threshold measurements with a Präcitronic KH 70 bone vibrator were carried out on 25 young, otologically normal subjects (50 ears) in the frequency range between 125 Hz and 8 000 Hz. The vibrator was applied to the human mastoid as well as to the forehead. The non-test ear was masked. Equivalent threshold force levels were determined on an artificial mastoid type B & K 4930. Between 125 Hz and 2 000 Hz, the equivalent threshold force levels for mastoid placement decrease steadily by about 13.5 dB/octave, they then increase again by about 10 dB and remain constant between 4 000 Hz and 8 000 Hz. The equivalent threshold force levels for forehead application were found to be higher by about 11 dB in the whole frequency range.

Adolescent↗

[Distribution of enterotoxinogenic strains among Staphylococcus aureus isolated from various sources].

A total of 406 S. aureus strains isolated from wound and mammal secretions in patients with wound infections and mastitis, from the throat of healthy children and those with respiratory disease, as well as during an outbreak of alimentary toxicoinfection, were studied. The capacity of these strains for the production of enterotoxins A, B, C, D, E, as well as the phage groups and phage types of these strains were determined. 34.2% of the strains were enterotoxigenic; the occurrence of this characteristic in staphylococci did not depend on the source of their isolation, but correlated with the results of their phage typing. Enterotoxigenic strains were detected most frequently (56.5--68.0%) in phage groups III, I/III and among staphylococci lyzed by additional phages (Nos. 88--96). Almost half of these strains produced enterotoxin A, each of other enterotoxins was produced by 12--14% of the strains. The isolated from the patients were found to produce mostly enterotoxins A and D, and those from healthy persons B and C. The relatively frequent production of enterotoxin D was found to be characteristic of staphylococci belonging to epidemic phagotype 80/81 isolated in mastitis.

Adult↗

[Studies of enterotoxin production by strains of Staphylococcus aureus of different origins (author's transl)].

376 Staphylococcus aureus strains of clinical and epidemiological origin were tested for their ability to produce the enterotoxins, A, B and C1. For these investigations, microagargel precipitation against specific antisera has been used. Additionally these strains were studied by phagetyping, biochemical typing and for their antibiogram. The strains tested came from human pathological processes, mouth throat swabs of healthy people, persons working in hospitals, outbreaks of food poisoning from cows suffering from mastritis and some from milk samples. Most of the strains isolated from food poisonings were associated with enterotoxin-A-production. Among the group of strains from autopsy material, the enterotoxin-B-producing strains were predominant. The strains from human pathological processes which were found to be enterotoxin producing, were mostly belonging to phage group III. With regard to the antibiogram, the enterotoxin-producing strains were somewhat more resistent than the enterotoxin-negative strains. Correlations between the production of enterotoxin B and methicillin resistance did not become evident in our material. The strains were differentiated, too, as to their classification as var. hominis or var. bovis. With one exception, all enterotoxin-producing strains which could be classified in this way, were belonging to var. hominis. From five enterotoxin-producing strains isolated from cattle, only one strain belonged to var. bovis, the other to var. hominis. Obviously the ability to produce the enterotoxins, A, B and C1 is very rare in the group of var. bovis strains.

Animals↗