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Biomedical subjects

U Mennicke

Publications and source records attributed to U Mennicke.

2 recordsLinked to original sources

Solid-supported lipid multilayers: structure factor and fluctuations.

We present a theoretical description of the thermal fluctuations in a solid-supported stack of lipid bilayers, for the case of vanishing surface tension gamma = 0 and in the framework of continuous smectic elasticity. The model is successfully used to model the reflectivity profile of a thin (16 bilayers) DMPC sample under applied osmotic pressure and the diffuse scattering from a thick (800 bilayers) stack. We compare our model to previously existing theories.

Computer Simulation↗

Dewetting of solid-supported multilamellar lipid layers.

Thin multilamellar assemblies of neutral lipid bilayers deposited on silicon substrates are shown to be unstable upon hydration. We analyze the stability of these systems taking into account a reduction of the fluctuation-related components of the bilayer interaction potential. The sizes of the patterns observed are consistent with a spinodal dewetting process.

Journal Article↗