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Biomedical subjects

U Mennen

Publications and source records attributed to U Mennen.

At least 19 recordsLinked to original sources

The evaluation of function of the flail upper limb classification system: its application to unilateral brachial plexus injuries.

The evaluation of function of the flail upper limb (EFFUL) classification system measures in numerical terms the improvement achieved through hand surgery and hand therapy in patients with peripheral nerve injuries. To research the effectiveness of the EFFUL system a study was conducted that included 103 adult traumatic brachial plexus palsies. The measurement of upper limb function has 2 distinct phases: function without adaptation and function with adaptation. Patients will naturally adapt in order to cope whether we encourage them or not. This jump in gain of function by adaptation is a bonus that cannot be measured for comparison with other patients because each patient is different. Differences include factors such as each individual's personal pattern of adaptation with or without assistive devices, intelligence, dominant hand, and, in particular, motivation. Measurement of preoperative and postoperative function (with its associated hand therapy) therefore may not include adaptation. The EFFUL system is a method developed to measure unadapted function; it measures residual function of the flail upper arm using practical, everyday tasks performed by the shoulder, elbow, forearm, wrist, and hand, ie, all upper limb regions. It is a ranking system with a hierarchy of increasingly higher demands placed on function until normal function has been achieved. The execution of the tasks focuses on 2-handed coordination and hand dominance. The score is divided into no function, minimal nondominant arm function, supportive arm (nondominant side) function, minimal dominant arm function, useful arm function as done by the dominant arm, and normal arm function. These descriptive scores are subdivided into scores ranging from 0 to 10. Thus, the EFFUL classification system is an objective method of measuring residual function before and after treatment. The clinical examination and functional evaluation ought to have equal significance in the final report on outcome. This approach to upper limb function is holistic but does not generalize in broad terms. An EFFUL-o-gram (patient profile) is used to record the progress and outcome of each individual patient.

Activities of Daily Living↗

Variations of the posterior interosseous nerve.

The posterior interosseous nerves of 58 cadaver forearms of black South Africans were dissected to study their order of branching. In 43 specimens (74%), the most common order of branching was: extensor carpi radialis brevis; supinator; extensor digitorum; extensor carpi ulnaris; extensor digiti minimi; abductor pollicis longus; extensor pollicis brevis; extensor pollicis longus and extensor indicis. In 15 specimens (26%) different variations of the nerve were observed, some of which are reported for the first time. The knowledge of these variations could be useful during operations in the vicinity of the nerve, and when repairing a nerve injury or forecasting the location of a compressive lesion.

Humans↗

Triplication of the thumb.

A child with triplication of the thumb is presented. Each thumb was fully developed with neurovascular bundles, flexor and extensor tendons. Although all three thumbs were triphalangeal, they shared a common metacarpal and two shared a common proximal phalanx. Since this anomaly does not fit in the existing accepted Wassel (1969) classification, a new category is suggested.

Humans↗

End-to-side nerve suture--a technique to repair peripheral nerve injury.

End-to-side nerve suture (ETSNS) has until recently been extensively researched in the laboratory animal (rat and baboon). Lateral sprouting from an intact nerve into an attached nerve does occur, and functional recovery (sensory and motor) has been demonstrated. We have demonstrated conclusively that ETSNS in the human is a viable option in treating peripheral nerve injuries, including injuries to the brachial plexus. Among the many advantages of this new technique are: (i) simple and short operation; (ii) shorter recovery time--suture is done closer to the target organs; (iii) nerve grafts to bridge injured gaps are eliminated, reducing the morbidity of nerve surgery to a minimum; (iv) innervation of paralysed muscles, for which there was previously thought to be no hope of recovery, opens up many new treatment options; and (v) certain aspects of nerve function and regeneration, unknown until recently, open new horizons and understanding. ETSNS has given us new dimensions in the management of peripheral nerve injuries.

Animals↗

Upper limb triplication with radial dimelia.

We report a very unusual case of upper limb triplication. The fused upper two limbs present as a duplicated mirror hand, joined along the ulnar side from the small finger up to the humerus. This exceptional abnormality further corroborates the theory that the development of the more distal segments of the limb is determined by the more proximal segments.

Amputation, Surgical↗

Side-effects of rinsing fluids on the rat femoral artery. A histological and electron microscopic study.

Rinsing rat femoral arteries with various fluids in experimental conditions similar to those in clinical practice was found to have deleterious effects on the intimal and medial layers of the vessels. No statistically significant difference was found between the effects of Ringer's lactate and normal saline. Heparinized saline produced significantly less damage to the medial layer and less platelet cell deposition. Lignocaine 2% was found to be extremely damaging to the whole vessel wall, and highly thrombogenic. Nevertheless, all the arteries in each group remained patent 4 days after rinsing.

Animals↗

The EFFUL (Evaluation of Function in the Flail Upper Limb) system. A ranking score system to measure improvement achieved by surgical reconstruction and rehabilitation.

The EFFUL (Evaluation of Function of the Flail Upper Limb) system measures in numerical terms the improvement, achieved through reconstructive surgery and hand therapy, in patients with brachial plexus injuries. The EFFUL system measures practical, everyday activities performed with the shoulder, elbow, forearm, wrist and hand. The ranking system is based upon a classification of function, with a hierarchy of increasing functional demands until normal function has been achieved. These activities focus on two-handed coordination and hand dominance. The score is plotted on a star histogram known as the patient's profile, and shows the preoperative score achieved in the first evaluation, and the postoperative score achieved in the second evaluation. The shaded area between the two plotted points clearly demonstrates any improvement in function obtained by surgery and rehabilitation. It also demonstrates the interrelationship between the various regions: improvement in function in one region often results in improvement in other regions.

Activities of Daily Living↗

Arthrogryposis multiplex congenita in a monozygotic twin. An intrauterine lesion?

Arthrogryposis multiplex congenita is a specific, well-defined congenital deformity which primarily affects muscles of limbs resulting in secondary joint deformities. The aetiology is still uncertain. One of monozygotic twin brothers with classical arthrogryposis multiplex congenita is presented, proving that this specific condition is not genetically transmitted.

Arthrogryposis↗

Early corrective surgery of the wrist and elbow in arthrogryposis multiplex congenita.

An early one-stage corrective surgical procedure for the elbow and wrist of patients suffering from arthrogryposis multiplex congenita is advocated. The procedure involves adequate proximal row carpectomy, tendon transfers to achieve a balanced wrist and a triceps to radius transfer for elbow flexion. Experience with 47 limbs showed that the best results were obtained in children operated on between 3 and 6 months of age.

Age Factors↗

Fingertip injuries management with semi-occlusive dressing.

We have developed a simple, cheap and efficient method of management of fingertip injury using a semi-occlusive dressing ("Opsite"--Smith and Nephew). The fingertip is covered with the "Opsite" once a week only. The dressing provides a temporary "skin", making the finger painless. This semi-occlusive "skin" allows the healing environment to reach an optimal milieu (e.g. pH, oxygen, tension, immunoagents) actively promoting granulation tissue formation and epithelialization. The result of 200 fingertip injuries treated with this method proves the development of a near normal pulp shape and useful epithelium within an average of 20 days.

Amputation, Traumatic↗

An alternative method of treating comminuted intra-articular fractures of the distal radius.

Comminuted intra-articular fractures of the distal radius will inevitably end in poor results if inadequately treated. We recommend an external fixator by two proximal and one distal Steinmann pins incorporated into a short plaster of Paris cast. This distraction method is easy, does not need special instrumentation, and is very cost-effective. Our method differs from previous methods in its simplicity and predictably good results if the recommended technique is followed.

Adult↗

Application of a quadriceps endurance programme to patients with femur fractures immobilised by skeletal traction.

Disuse atrophy of the quadriceps muscle and knee joint stiffness at the end of a 3-month period of immobilisation in patients with a fracture of the shaft of the femur is a common problem. A new approach to it was recently researched by applying a quadriceps endurance programme to a sample of this target population. Endurance capacity of matched experimental and control groups, consisting of 11 patients each, was tested at the end of the immobilisation period. Only the experimental group received the treatment intervention. Quadriceps endurance capacity in the experimental group at the end of the test period was at a 97% level compared with normal, uninjured subjects, while the control group's performance level was 57%. The difference is highly significant (P less than 0.0001). The problem of disuse atrophy had been successfully overcome in the experimental group. The unaffected leg of 10 patients from the same target population was also tested at the end of the immobilisation period. The mean value achieved was similar to the norm, i.e. there was no significant difference when compared with normal quadriceps endurance capacity.

Exercise Therapy↗

Extensor pollicis longus opposition transfer.

A new technique of opposition transfer uses the extensor pollicis longus tendon, which is sectioned just proximal to the metacarpophalangeal joint of the thumb, routed through the interosseous membrane, advanced subcutaneously across the anterior surface of the forearm but deep to the extensor pollicis brevis tendon, and sutured to its distal stump with a 1 cm overlap. This technique differs from th at of Riley et al. in several significant ways, although the same motor is used. Experience in 35 cases has yielded good or excellent results in 31 instances.

Adolescent↗

Elbow flexorplasty: a comparison between latissimus dorsi transfer and Steindler flexorplasty.

The latissimus dorsi transfer and the Steindler flexorplasty were compared to restore elbow flexion in seven cases. All patients had sustained upper trunk brachial plexus injuries and were adults of productive age. Both operations were successful. The results showed that the latissimus dorsi transfer provides more powerful elbow flexion and a greater range of movement one year post-operatively. The criteria for selection of candidates for both operations are set out.

Adult↗

Free plantaris (or tendo Achillis) osseotendinous transfer to restore finger flexion.

A new method to restore flexion of fingers is described whereby the plantaris tendon (or part of the tendo Achillis), with its bony insertion, is transferred to the finger. Strong bony anchorage is achieved in the distal phalanx, while a sound interweaving suture technique proximally in the palm will ensure enough strength to allow immediate mobilisation.

Achilles Tendon↗

Human fight-bite injuries of the hand. A study of 100 cases within 18 months.

100 consecutive patients whose finger had been bitten by another person, or who had cut it on a tooth in a fight, have been studied. 82 healed completely but 18 eventually needed amputation. Early and thorough debridement is required, plus a suitable mixture of antibiotics. Once infection is established in bone or tendon sheath, amputation is often needed, but most infected joints can be saved.

Adolescent↗