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Biomedical subjects

U Meldolesi

Publications and source records attributed to U Meldolesi.

49 records · Page 3Linked to original sources
PubMedDate not supplied

A controversial problem: is there a relationship between parathyroid hormone level and parathyroid size in primary hyperparathyroidism?

The current study was undertaken with the aim of studying the relationship between parathyroid hormone and hyperfunctioning parathyroids by a sophisticated method of analysis. Our clinical study included 25 patients undergoing surgery for primary hyperparathyroidism. The measurement of basal circulating intact PTH (pg/ml) and the volume (mm3) of the removed gland(s) were recorded. It was essential for the distribution of the sample values to be normal before Pearson's correlation and regression analysis were performed. The Kolmogorov-Smirnov test showed sufficient sample data agreement (p > 20%) with normal distribution after their transformation into natural logarithm (ln) and so statistical analysis was performed utilizing ln transformed data. The regression line between basal ln of iPTH levels (x) and ln of tumor volume (y) was highly significant (y = 2.3828 + 1.0424 x, r = .72504, p < .0001). In our opinion, the above is a correct statistical procedure with reliable results.

Adult↗
PubMedDate not supplied

Repeated 99mTc-Sestamibi studies for the evaluation of salvaged myocardium and of its relationship with postinfarction ischemia.

Pre- and post-treatment myocardial scans with 99mTc-Sestamibi demonstrated effective reperfusion after thrombolysis in a patient with acute myocardial infarction. Late follow-up images showed at rest a further noteworthy reduction of the uptake defect and that during exercise a large part of the salvaged territory became ischemic. This report demonstrates that a remarkable amount of myocardium in the posttreatment images was hibernated; furthermore, it was possible to visualize directly that the salvaged territory is the actual site of exercise induced postinfarction ischemia.

Heart↗