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Biomedical subjects

U Kleinhaus

Publications and source records attributed to U Kleinhaus.

At least 37 records · Page 2Linked to original sources

Ultrasonography in Crohn's disease.

Eighteen patients with acute and subacute Crohn's disease were examined by ultrasound. In 7, ultrasound was the initial screening procedure leading to the diagnosis of Crohn's disease. This diagnosis was subsequently proved by results of barium studies. The most frequent ultrasonographic finding was conglomeration: an irregular mass containing scattered echodense and sonolucent areas that represented matted inflamed bowel loops. Some of the conglomerations showed a fine diffuse echo pattern with ill-defined posterior borders due to poor transmission. These areas denoted mesenteric fat covering the matted loops (fatty conglomeration). Other ultrasonographic findings were the "target" or "bull's eye" sign, abscess formation, and fluid in the cul-de-sac.

Adult↗

Diagnostic radiology in wartime.

During the Lebanon War, 1982, over 80% of the wounded were sent from the triage area of the hospital directly to the radiology department. This article reports changes in the working pattern and organization of the department that were instituted for emergency treatment in wartime, and describes radiological examination methods for different organs. Computerized tomography is emerging as the most important diagnostic tool in addition to conventional radiological examinations.

Abdominal Injuries↗

Computed tomography in the diagnosis of adrenal pathology.

Computed tomographic diagnosis of adrenal pathology, based on experience with 13 cases, is presented. These include five pheochromocytomas, two functioning cortical adenomas and one case each of nonfunctioning adenoma, adrenal cyst with adenoma, carcinoma, metastasis, and bilateral hyperplasia. One additional case of a small adrenal tumor of undetermined nature was probably a small nonfunctioning adenoma. The smallest tumor detected was 25 mm in diam and the largest was 150 mm. Other imaging modalities employed were mainly conventional urography with tomography and ultrasonography. By these means only the larger adrenal tumors were detected. The relative merits and drawbacks of other imaging procedures are discussed and compared to computed tomography. Computed tomography should be the initial imaging procedure of choice when adrenal pathology is suspected.

Adenoma↗

Computed tomography-guided percutaneous drainage of right upper abdominal abscesses.

Definitive computed tomography-guided percutaneous drainage of right upper abdominal abscesses was performed in eight patients (11 procedures). A lateral perpendicular approach was used in all cases. An Argyl trocar catheter was used in nine procedures and a pigtail catheter in two. The drainage was successful in seven patients. In one patient no drainable abscess was found. Percutaneous abdominal abscess drainage should be considered a satisfactory alternative to surgical drainage in poor-risk patients as well as in patients who have had repeated operations in whom any further surgery may be unduly difficult.

Abdomen↗

Computed tomographic diagnosis of abdominal abscesses.

The CT signs of abdominal abscess are evaluated, based on experience gained with 41 abscesses in 38 patients. The majority of abscesses were located in the upper abdomen, the largest groups being 12 hepatic and 9 subphrenic. In 16 patients the abscesses were postoperative. The most common CT sign of an abdominal abscess was a homogenous low density lesion. Other primary signs were: well defined wall, mass effect and pathological extraintestinal gas. The role and types of contrast enhancement are discussed. Contrast enhancement are discussed. Contrast enhancement was not essential for the diagnosis of abdominal abscess in the majority of cases. The diagnosis of abdominal abscess by CT is compared to ultrasonography and conventional radiography.

Abscess↗

Splenic abscess diagnosed with the aid of abdominal computerized tomography: report of 2 cases.

Two patients with splenic abscess successfully diagnosed and treated are described. The first case, a diabetic, developed a pyogenic abscess caused by klebsiella, while the other suffered a splenic infarct complicated by splenic abscess. although relatively easy to treat, solitary abscess of the spleen is a potentially lethal condition due to diagnostic difficulties. In both present instances the final diagnosis was easily achieved before surgery by the aid of computerized tomography (CT). This investigation seems to be more accurate than 99Tcm-sulphur colloid scan and ultrasound scan, which failed in both cases to diagnose splenic abscess clearly. The use of this investigation is suggested in every suspected case and will, no doubt, confirm the diagnosis at an early stage of the disease. Splenectomy with antibiotic cover will usually result in cure.

Abscess↗

Sonographic features of gastrointestinal leiomyosarcoma.

Five cases of gastrointestinal leiomyosarcoma were studied by ultrasound. Sonographic features of a huge mass with a thick echogenic rim and central sonolucent cavitation were seen in four cases with presenting symptoms of an abdominal mass. In a fifth case necrotic metastasis was seen in the liver after removal of a leiomyosarcoma. Although not pathognomonic, such features should strongly suggest the diagnosis of leiomyosarcoma.

Aged↗

An analog patient model derived from computed tomograms for three-dimensional radiotherapy planning.

An analog model of the part of a patient's body containing a tumor is constructed by drawing anatomical contours obtained from computed tomograms on a set of transparent plastic sheets. The coverage of radiotherapy fields in the patient is visualized in three dimensions using the model and the light beam from the radiotherapy machine or a simulator. A clinical example is presented.

Humans↗

Long bone growth during prolonged intermittent corticosteroid treatment and subsequent rehabilitation.

Immature A/J mice were treated for up to 7 weeks intermittent doses of triamcinolone hexacetonide and were thereafter allowed to recover for 7 weeks. Qualitative and quantitative morphological measurements were performed on the epiphyseal cartilage plate and diaphyseal bone of the humerus. By the third injection significant structural changes were noted in the cartilaginous tissue followed by a complete cessation of bone growth. The hormonal inhibitory effect on long bone growth lasted throughout the experimental period. However, at the end of the recovery period the length of the humerus was 96% of the normal. In contrast, the humeral width at midshaft and the width of its medullary cavity revealed slower recovery, achieving only 80% of the control values. Following rehabilitation, the growth of experimental epiphyseal plates exceeded that of nontreated animals as their width and the number of hypertrophic chondrocytes were 131% and 125% of their controls respectively. Thus, in A/J mice (a highly susceptible inbred strain of mice) intermittent (every four days) administration of a long-acting corticosteroid hormone arrested endochondral and periosteal bone formation; the former, however, underwent full recovery following the termination of the hormonal treatment.

Animals↗

Rectosigmoid pseudostenosis due to urinary retention.

Pseudostenosis of the rectosigmoid colon due to compression by a dilated urinary bladder may pose a diagnostic problem. Although probably quite common, it has not received much attention in the radiological literature. Four cases are presented and the radiological features on barium enema are described.

Aged↗