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Biomedical subjects

U Jonsson

Publications and source records attributed to U Jonsson.

47 records · Page 3Linked to original sources

External fixation for redislocated Colles' fractures.

Rereduction was carried out in 5% of all treated Colles' fractures and they were externally fixated with a one-bar Hoffmann apparatus. The results of 57 of the first 69 patients treated with a follow-up time of at least 1 year are presented. Using Frykman's criteria, 18 patients were judged as "excellent", 25 as "good" and 14 patients were judged as "unsatisfactory". The anatomical analysis showed no increase of deformity during the fixation. The final mean results were a 3.0 mm radial shortening and the articular plane of the radius at a right angle to the long axis. Among the first patients, five cases of pin-loosening were seen, but there were no adverse effects in the final result. There were no pin-tract infections. The results justify using the method as a routine when a redislocated Colles' fracture is rereduced.

Adult↗

Thermal inactivation of a heat-resistant lipase produced by the psychotrophic bacterium Pseudomonas fluorescens.

Lipase from Pseudomonas fluorescens was studied for thermostability at temperatures ranging from 100 C to 160 C. The heat treatments were in two media, and heating times necessary to inactivate 90% of the enzyme at constant temperature were extremely long even at high temperatures, e.g. 3.6 min at 140 C in nutrient broth and 2.0 min at 170 C in skim milk. The increments of temperature to reduce these heating times 90% were 37.0 C in nutrient broth and 38.9 C in skim milk. The lipase was inactivated only partly after 20 h at 20 C in 8 M urea, 6 M guanidine hydrochloride, and 1.0% sodium dodecyl sulfate. Four percent 2-mercaptoethanol showed no effect.

Animals↗

Autoxidation of N-hydroxyphenylalkylamines: the inhibitory effect of some anions on copper catalysed autoxidation of N-hydroxyphentermine.

The inhibitory effect of certain electrolytes and buffers on the copper catalysed autoxidation of N-hydroxyphentermine (2-hydroxylamino-2-methyl-1-phenylpropane) has been investigated. The presence of ions such as SO4(2-), Cl- or Br- markedly reduced the rate of oxidation. Phosphate and carbonate buffers had a similar effect with halides and phosphate buffers being the most inhibitory. The occurence of 2-methyl-2-nitro-1-phenylpropane and 2-methyl-1-phenylpropene-(1) as secondary oxidation products was also established.

Buffers↗