Biomedical subjects

U Hanson

Publications and source records attributed to U Hanson.

40 records · Page 3Linked to original sources

PubMed1983

Glycosylated hemoglobins in normal pregnancy: sequential changes and relation to birth weight.

In order to evaluate changes in hemoglobin A1 levels during nondiabetic pregnancy, 19 pregnant women were followed by determination of hemoglobin A1 with a two to four week interval. There was an early decrease in the hemoglobin A1 level already between the 12th and 16th weeks of pregnancy, with a further decrease in the course of the pregnancy. This physiologic fall in hemoglobin A1 during nondiabetic pregnancy could be important in evaluation of hemoglobin A1 changes in diabetic pregnancies. Correlations between different levels and changes in hemoglobin A1 and relative birth weight were also calculated. Relative birth weight was best correlated to the changes in hemoglobin A1 during the third trimester (r = 0.56, P less than .01), which suggests that availability of glucose is one factor determining fetal growth during the last trimester.

Birth Weight↗

PubMed1982

Psychophysiological stress responses in postmenopausal women before and after hormonal replacement therapy.

Seventeen females with a history of hot flushes, perspiration, and amenorrhea of at least 6 months' duration, and a serum FSH level exceeding 40 IU/l entered a cyclic treatment with 17 beta-estradiol and estriol combined with norethsterone (Trisekvens, Novo). Each patient took part in three experimental sessions, six weeks apart, in which stress was induced by mental performance tests. To permit separation of treatment and habituation effects the patients were randomly assigned to one of two groups, Group 1 starting therapy after the first, Group 2 after the second session. Treatment eliminated hot flushes and perspiration and reduced serum FSH levels without causing changes in blood pressure or heart rate. There was no correlation between hormonal treatment and excretion of catecholamines during stress. Testosterone and androstenedione serum levels remained unchanged during therapy. Self-reports showed that tiredness, headache, tension and anxiety were significantly reduced following treatment.

Adult↗

PubMed1981

Dosage of insulin during delivery and the immediate post-partum period in pregnant diabetics.

Several different principles have been presented for treatment of the pregnant diabetic in connection with labor. There is, however, a lack of documentation of blood glucose levels in the immediate post-partum period. On the day of delivery and on the 2 following days, 55 diabetics were given one daily injection of an intermediate-acting insulin, irrespective of the mode of delivery. The amount of insulin given was one-third of the total dose on the day before delivery. From 07.00 hours on the day of delivery, blood-glucose levels were determined every fourth hour for 48 hours. This insulin dosage gave a satisfactory control of glycemia with a low incidence of hypoglycemia and additional insulin was very seldom required.

Adolescent↗

PubMedDate not supplied

Effect of treatment with insulin or diet on intermediary metabolites in pregnant women with chemical diabetes in the third trimester of pregnancy.

The diurnal (07(30) - 16(00) profiles of glucose, 3-hydroxybutyrate (3-HB), non-esterified fatty acids (NEFA), and glycerol were studied in 19 pregnant women with gestational diabetes and eight pregnant non-diabetic controls. Nine of the gestational diabetic women were treated with intermediate and in some cases with fast acting insulin and diet and 10 were treated with diet alone. Although fasting plasma glucose levels were normal (less than 6.0 mmol/l) in 8 insulin-treated and 9 diet-treated gestational diabetics before the start of treatment, the profiles of glucose, NEFA and glycerol were generally higher in gestational diabetic compared to non-diabetic pregnant women. The insulin-treated group had lower, but not normal, plasma glucose and higher levels of glycerol than the women treated with diet only. The levels of 3-HB and NEFA were not significantly influenced by the type of therapy. It is suggested that treatment of gestational diabetes should consist of multiple injections of fast acting insulin.

3-Hydroxybutyric Acid↗