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Biomedical subjects

U Haller

Publications and source records attributed to U Haller.

At least 127 records · Page 7Linked to original sources

[Surgical gynecology today and tomorrow. Main topic of the 13th Academic Congress of German-Speaking Faculty of Gynecology and Obstetrics, Hannover, 16-19 May 1993. 2: Hysterectomy, ambulatory surgery and laparoscopy].

It is shown how in gynaecologic oncology, proceeding from former standardized techniques, an individualized multimodal therapeutic concept has been developed. New aspects are introduced concerning diagnosis and treatment in the field of operative urogynaecology. The world-wide problem of performing poorly indicated hysterectomies is also addressed. Dynamic developments in the field of out-patient surgery will become an increasing challenge in the near future, influencing obstetrics and gynaecology to an extent that cannot be present be foreseen for the middle and long range. The forced evolution of conventional and laser-assisted laparoscopic surgery resulted in a nowadays broad spectrum of laparoscopically practicable surgical interventions, which made, even if still questioned by some experts, the vaginally assisted laparoscopic hysterectomy possible.

Ambulatory Surgical Procedures↗

Electrical cutting device for laparoscopic removal of tissue from the abdominal cavity.

The extraction of large tissue masses from the abdominal cavity during laparoscopic surgery is a time-consuming, complicated process. A new prototype instrument is introduced that allows quick laparoscopic removal of fibromas, ovaries, or other tissues from the abdomen. A cylinder with a coning knife at its intra-abdominal end is placed inside the trocar sleeve and is rotated by an electrical micro-engine attached to the trocar. Cylindrical tissue blocks are cut step by step out of the main specimen and removed from the peritoneal cavity through the sleeve with a grasping forceps. Tissue removed is suitable for histologic examination. The principal application is morcellation of fibromas, whereas use in ovarian disease is limited. This new device provides a safe and effective approach inside the abdominal cavity.

Electrosurgery↗

[Differential diagnosis of breast tumors with eczematous breast changes: two rare cases].

It is reported upon two patients who were presented to us to evaluate suspicious tumors of the breast: A 64-year-old patient had very painful tumors in both breasts measuring four centimeters in diameter with additional eczematous lesion of the left mamilla, which has developed within the last weeks. For many years she suffered of a pseudoxanthoma elasticum (PXE) of the skin combined with arterial occlusion disease. Histologically these tumors showed necrosis and typical signs of PXE, which is to our knowledge the first case reported in literature. A 79-year-old patient showed an inverted eczematous nipple, combined with a retromamillar painless tumor of the left breast. The histology was Paget's disease with an underlaying ductal carcinoma. --The clinical picture and the diagnosis are presented, followed by the discussion and the differential diagnosis.

Aged↗

[Significance of the intercostobrachial nerve in axillary lymph node excision].

The anatomy of the intercostobrachial nerves is described; generally two or three of them exist on each side. We followed up 101 modified radical mastectomies with axillary dissection: 53 cases (52.5%) had no sensory disturbances of the intercostobrachial nerves, 48 (47.5%) had either a loss of sensibility or dysesthesias. 8 patients (7.9%) showed an intercostobrachial nerve entrapment syndrome grade I, whereas 4 (3.96%) patients complained of a more intense pain syndrome (2 x grade II, 2 x grade III).

Adult↗

[PERGYN: perinatal-gynecologic information system].

PERGYN is a scientific research project of a purely medical nature. Its goal is to procure and evaluate the entire body of perinatal and gynaecological data in all its complexity. Data input is based on standardized medical concepts. Further details on the medical concept are stored in a course tree. In conjunction with the interview machine the course tree creates storable medical data. Data evaluation criteria are definable in dialogue on screen. Other medical areas can also be integrated into the data model. The conversion of medical constituents of the course tree calls for a process as "knowledge engineering".

Diagnosis, Computer-Assisted↗

Weight percentile at birth. II. Prediction by endocrinological and sonographic measurements.

In a prospective study of 847 singleton pregnancies, the importance of various endocrine methods (serum estriol, HPL, SP1, beta-HCG, estradiol-17 beta, urinary estrogen excretion) and of two sonographic measurements (biparietal and thoracic diameter) for the diagnosis of growth retardation in the third trimester was studied. HPL and estriol determinations were best suited for the diagnosis of growth retardation. The thoracic diameter correlated most closely with the birthweight of the newborns. Sensitivity in relationship to growth retardation was between 17 and 35% for the HPL and estriol determinations as well as for both sonographic methods. Specificity was around 90% for these methods. The validity for all methods improved as the time of birth approached. Through the simultaneous measurement of one of the hormones and the thoracic diameter, an antepartal diagnosis of up to 50% of the hypo- and hypertrophic growth disorders was achieved. In the first two years of life a relationship between development and the HPL and estriol concentrations could be observed which was independent of the weight percentile at birth.

Birth Weight↗

A randomized study of a semisynthetic heparin analogue and heparin in prophylaxis of deep vein thrombosis.

The prophylactic effect of a semisynthetic heparin analogue (SSHA) on deep vein thrombosis was investigated in a prospective double-blind multicentre trial. 440 major general surgical and gynaecological patients were randomized to one of three treatment groups: 50 mg SSHA, 37.5 mg SSHA and 5000 units sodium heparin subcutaneously 12-hourly. Deep venous thrombosis (DVT) was diagnosed with the fibrinogen uptake test and verified with phlebography. Bleeding complications and other side-effects were carefully monitored. There were no significant differences between the three treatment groups of patients in age, sex, type of operation or risk factors. A DVT was diagnosed in 16 patients (12 per cent) in the SSHA 50 mg group, in 21 patients (15 per cent) in the SSHA 37.5 mg group and 21 patients (14 per cent) in the heparin-treated group. No significant differences were found in the number of patients who bled unexpectedly in the postoperative period, required transfusion or developed wound haematomas. Blood loss at operation was similar in all three groups. Three pulmonary emboli were diagnosed by pulmonary scintigraphy, one in each group.

Adult↗

[Ovarian cancers--a solution within reach?].

The overall 5-year survival rate for ovarian malignant tumors is approximately 25-30%. Ovarian cancer is usually recognized and diagnosed too late. Malignant ovarian tumors show a variety of biological and clinical features, as well as a wide spectrum of histiogenesis and histologic findings. The present study deals with epithelial ovarian tumors (80% of all malignant ovarian tumors): serous, mucinous, endometrioid and undifferentiated carcinoma. The incidence of malignant ovarian tumors varies between 2.5 in Japan and 15.1 in Sweden. The aim of surgical treatment lies in the radical removal of tumor masses without producing higher morbidity or mortality figures. Whenever possible the surgical treatment consists of median laparotomy, cytologic, anatomical and histologic staging, as radical as possible tumorectomy, hysterectomy with bilateral adnexectomy, omentectomy, and appendectomy. The prognosis of ovarian cancer depends on histologic findings, and also on the modalities of primary treatment. Further important prognostic factors are residual tumor masses after surgical treatment, the patient's age, the degree of differentiation and the extent of the tumor. Diagnosis, monitoring of patients and follow-up are directly influenced by dissemination of the tumor. Second-look laparotomy is the only reliable method of obtaining data in follow-up of the disease. Clinical assessment is important but insufficient in considering further treatment. Adjuvants to radical surgical treatment are chemotherapy and radiotherapy, for which the indications and therapy schedule are described.(ABSTRACT TRUNCATED AT 250 WORDS)

Antineoplastic Combined Chemotherapy Protocols↗

Continuous pH-measurement on anesthetized patients.

43 patients under general anesthesia were monitored by continuous tissue pH measurement and intermittent micro-blood-samples. The values obtained for the capillary pH and tissue pH were correlated. A highly significant correlation was found between tissular pH and capillary pH. Different methods of general anesthesia apparently do not influence the continuous tissue pH measurement.

Anesthesia, General↗

A new application tool for the ROCHE pH electrode.

Using this tool the application of the pH electrode is nearly as easy as the attachment of a common ECG-scalp-electrode [3]. Visual control and lithotomy position is not necessary any more. The different tools are adapted to each other so that incision place and the tip of the pH electrode are automatically centered perpendicularly. The first results by using this tool promise to be successful. Time of application is short, the maintenance of the pH electrode is good and the application for the patient no longer disagreeable.

Electrodes↗

Continuous tissue pH measurement on the fetus during delivery.

Tissue pH values of 70 fetuses have been measured continuously during labor using the micro-electrode designed by Stamm. Significant correlation between continuous tissue pH and corresponding micro blood values can be shown. However, the relationship between patterns of tissue pH and capillary pH values seems not to be very constant. Therefore, the reliability of individual tissue pH measurements is still questionable.

Capillaries↗