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Biomedical subjects

U H Sjostrand

Publications and source records attributed to U H Sjostrand.

3 recordsLinked to original sources
PubMed1985

Conventional and high-frequency ventilation in dogs with bronchopleural fistula.

Seven anesthetized dogs with bronchopleural fistulas were subjected to a sequence of continuous positive-pressure ventilation (CPPV), volume-controlled high-frequency positive-pressure ventilation (HFPPV), and high-frequency vibratory ventilation (HFVV). Adequate short-term ventilation and oxygenation were possible with all three ventilatory modes. During HFPPV and HFVV, PaCO2 was unchanged, but hypercarbia developed during CPPV. PaO2 decreased during each mode of ventilation, but HFPPV maintained PaO2 at a sufficient and constant level during the 30-min test period. HFPPV was the most efficient technique with respect to delivery of minute ventilation, the relation between fistula flow and delivered ventilation, and maintenance of both ventilation and oxygenation.

Animals↗
PubMed1984

Regional organ blood flow during high-frequency positive-pressure ventilation (HFPPV) and intermittent positive-pressure ventilation (IPPV).

The effect of high-frequency ventilation (HFV) on cerebral blood flow (CBF) at normal and elevated intracranial pressure (ICP) was compared with flows measured under the same conditions during intermittent positive pressure ventilation (IPPV). Renal, lung (bronchial artery supply), and cardiac blood flows also were measured during HFV and compared with flows observed during IPPV. Measurements were made in canines with stable hemodynamic variables and arterial CO2 and O2 tensions in the normal range, CBF during HFV was comparable to the CBF during IPPV. Following an increase in ICP to a mean of 44 +/- 18 mmHg (SD), mean CBF decreased to 22.5 +/- 11 ml . 100 g-1 . min-1 (SD) during IPPV and 21.7 +/- 13.2 ml . 100 g-1 . min-1 (SD) during HFV. No statistical differences could be noted in regional or global flow as a function of ventilatory mode. Renal, lung (bronchial artery supply), and cardiac blood flows also showed no statistical variation between HFV and IPPV. Ventilator-synchronous fluctuations in ICP observed during IPPV were reduced during HFV at normal ICP and eliminated by HFV at elevated ICP.

Animals↗