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Biomedical subjects

U Fisch

Publications and source records attributed to U Fisch.

At least 109 records · Page 6Linked to original sources

Modified transotic approach to the cerebellopontile angle.

A modification of the transotic approach to the cerebellopontile angle involves complete removal of the otic capsule bone, obliteration of the middle ear cleft, and removal of the posterior external auditory canal wall, while leaving the fallopian canal intact. The major advantage of this technique is that it allows more direct visualization of the most vulnerable portion of the facial nerve medial to the anterior wall of the internal auditory canal during acoustic tumor removal.

Cerebellopontine Angle↗

Management of sudden deafness.

Measurements according to the polarographic principle in cats have shown that the factors influencing the perilymphatic oxygen tension are the arterial PCO2, the arterial PO2, and the systemic blood pressure. In patients with sudden deafness, the oxygen supply to the vestibular tissues is significantly reduced but the response to carbogen is still possible. The vasodilation induced by carbogen in sudden deafness is not accompanied by a reduction (stealing effect) but by an increase of perilymphatic oxygenation. Therefore carbogen inhalation was used for the treatment of sudden deafness. In a prospective randomized study, carbogen inhalation yielded significantly better results than the intravenous infusion of papaverine and low-molecular dextran. Carbogen inhalation is recommended for the effective, noninvasive treatment of sudden deafness.

Animals↗

The infratemporal fossa approach for nasopharyngeal tumors.

The technique and results of the infratemporal fossa surgical removal of carcinomas and juvenile angiofibromas of the nasopharynx are presented. Effective palliative removal of T4 and radical removal of T1 and T2 nasopharyngeal carcinomas was achieved. A classification of juvenile nasopharyngeal angiofibroma is presented. The infratemporal fossa approach allows radical removal of type III tumors and subtotal removal of type IV tumors. If residual tumor has to be left back in the cavernous sinus, irradiation is used to stop further growth of the tumor. If radiotherapy fails the neurosurgical removal of the intracranial portion of the tumor is indicated.

Adolescent↗

Effect of diatrizoate meglumine (Hypaque) on the perilymphatic oxygen tension.

The effect of diatrizoate meglumine (Hypaque) upon the perilymphatic oxygenation has been investigated using the polarographic method in cats submitted to various conditions such as normoxia, apnea, hypercapnia and chronically reduced vascularization. The minimal changes of the perilymphatic PO2 recorded after the injection of Hypaque permit to conclude that this drug has no practical effect upon the oxygenation of the perilymph.

Animals↗

[On the problem of the congenital (?) cholesteatoma of the petrous bone (author's transl)].

The congenital cholesteatoma of the petrous bone is a rarity. The topographic situation corresponds to a congenital dermoid. The evolution is typic. On the beginning the ear drum is intact, very early one will find a loss of the labyrinth function, often accompanied by a facial paresis. The suppuration of the middle ear comes in a later state. The drainage operation is insufficient. The subtotal petrosectomy with permanent anterior dislocation of the facial nerve gives the chance for a definitive healing.

Adult↗

Stapedotomy versus stapedectomy.

The postoperative results in 392 otosclerotic ears were analyzed. Stapedotomy with wire Teflon piston does not increase the risk of postoperative fistula formation in comparison to stapedectomy with tissue graft sealing. Stapedotomy with a 0.4 mm wire Teflon piston yields poorer results in the lower frequencies 3 weeks postoperatively but results as good as those of 0.6 mm stapedotomy at 3 months and 1 year follow-up. The advantage of 0.4 mm stapedotomy is to permit creation of the desired fenestra into the footplate and placement of the prosthesis before violating the integrity of the incudostapedial joint and of the stapedial arch. Stapedotomy with the 0.4 mm wire Teflon piston is the operation of choice for otosclerosis, since it is less traumatic to the inner ear and achieves better results than stapedectomy.

Bone Conduction↗

Surgery for Bell's palsy.

Electroneuronographic study of the spontaneous course of Bell's palsy shows that chance of a satisfactory spontaneous return of facial function is reduced by 50% when 95% or more maximal degeneration is reached within two weeks of onset. For this reason immediate surgical decompression (including the meatal foramen) was performed on 14 patients with 90% or more degeneration within three weeks of palsy onset. These patients and 13 who refused treatment under similar conditions were reviewed one to three years later by three physicians familial with facial nerve problems. Results show that to obtain satisfactory (80% to 100%) return of facial movements in all cases of Bell's palsy, surgical decompression should be performed within 24 hours when degeneration reaches 90% to 94% within one to 21 days after onset. By using these guidelines, the number of unnecessary operations will be kept under 16%.

Adult↗

Glomus tumors of the temporal region. Technique of surgical resection.

Since a previous study conducted at the Ear, Nose and Throat Department, University Hospital, in Zurich, Switzerland, 16 additional cases of glomus jugulare of the temporal region have been evaluated and treated surgically in this department. This article describes our experience with these additional cases and gives an in-depth description of the surgical techniques that are used in the treatment of more complicated tumors. We report one case in detail.

Adult↗

Polyarteritis nodosa as a cause of sudden deafness. A human temporal bone study.

Pathological changes in the temporal bone are described in a case of polyarteritis nodosa in a 48 year old man in whom the onset of sudden unilateral deafness and vertigo occurred seven months prior to death as one of the early manifestations of the disease. The patient had received only a seven week course of prednisolone and, earlier, a two week course of anti-inflammatory agents. Autopsy revealed involvement of the arteries supplying the kidneys, testes, and pancreas. Changes within the temporal bone were seen bilaterally and there was thickening of the mucosa of the middle ear. Inner ear involvement was mainly limited to the cochlea, the deaf ear showing more pronounced changes. These changes included loss of the organ of Corti in the hook portion of the basal coil, absence of the tectorial membrane, and atrophy of the stria vascularis. The scala tympani was obliterated by fibrosis and new bone formation. The scala media showed hydrops, and a marked decrease in the spiral ganglion cells and nerve fibers supplying this portion of the cochlea was evident. Focal changes were seen throughout the remainder of the cochlea. The vestibular structures showed no detectable pathologic changes. Small vessel arteritis was found in the dural and subacuate vessels in both temporal bones.

Arteries↗

Experimental study on the perilymphatic pressure.

The hydrostatic pressure was successfully and accurately measured through the round window membrane of the cat over a wide pressure range and long duration using glass micropipets of 1-5 micrometer tip inner diameter and an active nulling pressure measuring system. The dynamic changes in perilymphatic pressure occurring after inhalation of different gas mixtures (5 percent CO2 and 95 percent O2/carbogen, 5 percent and 10 percent CO2 in room air) were recorded. The maximal oxygenation of the perilymph combined with minimal increase in pressure was achieved following inhalation of carbogen. The correlation between variations of pressure of the perilymph and of the systemic blood circulation shows that a regulatory system is present in the inner ear vessels. The pressure measuring system used has proven to have all the requirements that are needed for its use in humans.

Animals↗

Maximal nerve excitability testing vs electroneuronography.

In an article published in 1977, Adour et al compared electroneuronography (neuromyography) with maximal nerve excitability testing (NET) and reached the conclusion that the prognostic value of the latter was more reliable in facial paralysis. Further analysis of the results of Adour et al leads, however, to the opposite conclusion and illustrates how one may avoid the pitfalls that exist in using electrical stimulation to evaluate facial nerve function. Certainly, electroneuronography (ENoG) is not a foolproof method and experience is needed in order to avoid errors in technique and to achieve reproducible results. The great advantage of ENoG vs maximal NET is the quantitative analysis of the number of degenerated fibers and the assessment of an accurate degeneration profile in Bell's palsy.

Action Potentials↗