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Biomedical subjects

U Fisch

Publications and source records attributed to U Fisch.

At least 73 records · Page 4Linked to original sources

The infratemporal fossa approach for adenoid cystic carcinoma of the skull base and nasopharynx.

The infratemporal fossa approach to the skull base is an established method of treating neoplasms of this region. The type C variation has proved an effective means of removing adenoid cystic carcinoma invading the infratemporal fossa and skull base from the nasopharynx. A classification of these tumors is proposed, the surgical technique is described, and the results are given in this article.

Adult↗

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Journal Article↗

Facial nerve grafting.

The techniques of facial nerve grafting have undergone several adjustments and refinements within the last 20 years. Those techniques that have stood the test of time are discussed, and new approaches to facial nerve grafting in the temporal bone are explored.

Facial Nerve↗

Radical mastoido-epitympanectomy with tympanoplasty and partial obliteration: a new surgical procedure?

The modern concept of an open cavity is to combine a safe with a dry, self cleansing ear. The prerequisites to achieve this goal are: the radical exenteration of the mastoid, antrum and epitympanum, the maximal reduction of the volume of the cavity by extensive lateral removal of bone and the adequate shaping of the cavity walls by obliteration of the bone pockets. To perform correctly a radical mastoido-epitympanectomy with tympanoplasty and partial obliteration is difficult and requires a perfect anatomical knowledge of the deepest regions of the temporal bone, particularly of the supralabyrinthine space. Using the technique exposed in this article, 75 out of 79 ears (95% of our revision cases) achieved a dry and self cleansing cavity at three years follow-up.

Cholesteatoma↗

Long-term results of treatment for children's cholesteatoma.

Fifty-seven of 98 children with cholesteatoma treated between 1976 and 1985 were available for long-term follow-up. The clinical records of the 57 children were analyzed retrospectively. The purpose of this study was to compare the incidence of recurrent and/or residual cholesteatoma, postoperative otorrhea, and hearing results between two groups of patients. One group (n = 40) of children was treated with a radical mastoidoepitympanectomy (RMET) and the other group (n = 17) was treated with intact canal wall tympanoplasty/mastoidectomy (ICWT). Residual cholesteatomas were twice as frequent (17% versus 7.5%) in the ICWT group while recurrent disease was the same. There was no difference in postoperative otorrhea between the two patient groups. Hearing results were equally good in the Type III and in the ICWT group with staged TORP. It is concluded that a Type III tympanoplasty is an excellent one-stage method of hearing reconstruction in patients with good eustachian tube function and an intact stapes and that a correctly performed RMET offers a safe trouble free alternative to ICWT. In selected patients with limited disease and a well pneumatized mastoid, ICWT is still used.

Child↗

Intratemporal facial nerve anastomosis: a temporal bone study.

The temporal bone findings in a patient who suffered a transverse temporal bone fracture and subsequently underwent intratemporal facial nerve anastomosis are presented. The patient returned a year after surgery with otorrhea and partial return of facial function that was documented clinically, and by electromyograph 12 days before death. The temporal bone shows breakdown of the posterior external canal wall and infection of the surgical cavity. At the facial nerve anastomosis, there is a fibrosis and lack of myelination in the few regenerating nerve fibers. These results demonstrate a seldom-mentioned complication of the translabyrinthine approach, and suggest changes in the technique of facial nerve anastomosis to improve the results.

Adolescent↗

Neural infiltration of glomus temporale tumors.

Biologic behavior of glomus temporale tumors in relation to cranial nerve infiltration remains unclear. An analysis of cranial nerve involvement in relation to tumor staging was undertaken in a series of 102 glomus temporale tumors. Frequent neural infiltration was noted to occur in large glomus tumors, and a grading system of infiltration with both pathologic and surgical relevance introduced.

Adolescent↗

Central neurofibromatosis: a clinical-pathological correlation.

Central neurofibromatosis is a genetic disorder of neural crest tissue derivatives that includes bilateral acoustic neuromas and other central nervous system tumors, usually meningiomas or gliomas. This is different from peripheral neurofibromatosis because of the primary central nervous system manifestations and frequent lack of accompanying peripheral neurofibromas and café au lait spots as well as different alterations of nerve growth factor. We present the temporal bone histopathology of a unique case of unsuspected central neurofibromatosis that included bilateral acoustic neuromas invading the cochlea and an asymptomatic glioblastoma multiforme occurring in the absence of a family history and without any accompanying peripheral stigmata of neurofibromatosis. As bilateral tumors frequently invade the cochlea, the modified transotic rather than the translabyrinthine approach is recommended for complete tumor removal. Contralateral tumor removal should be delayed while useful hearing remains.

Brain Neoplasms↗

The fallopian canal and facial nerve in sclerosteosis of the temporal bone: a histopathologic study.

Sclerosteosis is an uncommon subtype of osteopetrosis that is frequently associated with recurrent facial nerve palsy. Because of the need for detailed measurements of the fallopian canal and facial nerve in this disease, a study was carried out using a new method of surface area measurement. The results show narrowing of the fallopian canal and facial nerve in the labyrinthine, distal tympanic and mastoid segments. Maximum surface area loss occurred in the labyrinthine segment for both the canal and nerve. In addition, bony occlusion of the stylomastoid artery was found. From these findings we conclude that ischemia and bony compression are the underlying causes of recurrent facial palsy in this disease. We also conclude that because the labyrinthine segment is the most severely affected, surgical decompression must include this portion of the fallopian canal.

Adult↗

Menière's symptoms resulting from bilateral otosclerotic occlusion of the endolymphatic duct: an analysis of a causal relationship between otosclerosis and Menière's disease.

An association between otosclerosis and Menière's disease has been proposed on both a clinical and temporal bone histopathologic basis for well over three-quarters of a century. Controversy persists over a causal relationship between these two entities, however, and the underlying pathophysiologic mechanisms relating capsular otosclerosis with Menière's disease remain speculative. The first case of total, bilateral endolymphatic duct occlusion resulting from extensive capsular otosclerosis is presented in a woman manifesting Menière's symptoms. The severe endolymphatic hydrops resulting from otosclerotic endolymphatic duct occlusion is given as histopathologic proof of a causal relationship between these two entities. Analysis of 18 of our own temporal bone cases of extensive capsular otosclerosis without endolymphatic hydrops and review of the literature indicates the uniqueness of such a firm causal relationship in the present case.

Adult↗

Preauricular pilomatrixoma: a diagnostic pitfall.

Although pilomatrixomas are well known to dermatologists and dermatopathologists, surgeons encountering these lesions over the parotid gland frequently do not consider this benign neoplasm in the differential diagnosis. Presentation of a subcutaneous preauricular lesion, coupled with an erroneous cytologic diagnosis of malignancy, can potentially result in histologic "overdiagnosis" and more aggressive therapy than is required for these benign hair follicle neoplasms. A case is reported to illustrate this potential diagnostic trap, and a series of 206 cases collected at the University Hospital of Zurich from 1975 to 1987 is reviewed.

Adolescent↗

Lesions of Rathke's duct: another indication for the infratemporal fossa approach.

Rathke's duct is a midline structure, arising from the primitive stomodeum and extending upward to the hypophysis. The duct, which normally involutes in utero, may persist on occasion. This most frequently results in intracranial disease. Occasionally, disease may become manifest in the extracranial skull base. We present three such cases: cystic craniopharyngioma, Rathke's cleft cyst, and a persistent cerebrospinal fluid rhinorrhea caused by a patent craniopharyngeal canal. Each lesion involved the clivus and the parasphenoid region. Surgical management of such lesions requires not only extirpation of disease, but also the ability to recognize and preserve the many important regional structures. The procedure that best allows for the wide exposure necessary to accomplish these goals is the infratemporal fossa approach to the lateral skull base.

Cerebrospinal Fluid Rhinorrhea↗

Jugular foramen peripheral nerve sheath tumors.

Though jugular foramen nerve sheath tumors are uncommon, they involve a critical area of the skull base. Therefore, a precise classification system is needed to accurately define the extent of these tumors and reflect their surgical management. A series of seven cases is reviewed incorporating such a classification system to illustrate the management of these lesions using the infratemporal fossa type A approach.

Adolescent↗

Malignant transformation of a nasopharyngeal angiofibroma.

The malignant transformation of a nasopharyngeal angiofibroma is a rare occurrence. This report describes the development of a fibrosarcoma in a patient over a 20-year period after four surgical procedures and two courses of radiation therapy to control a nasopharyngeal angiofibroma. A review of the literature revealed similar descriptions of this problem. Radiation likely plays a major role in causing the malignant change. An initial complete surgical excision can prevent recurrence of a nasopharyngeal angiofibroma as well as sarcomatous transformation. With the availability of surgical procedures that can completely and safely resect almost all nasopharyngeal angiofibromas, radiation therapy can be avoided.

Adolescent↗

The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach.

Large juvenile nasopharyngeal angiofibromas are a therapeutic challenge because of their relation to major vasculature and cranial nerves at the base of the skull, and their propensity for recurrence. A classification scheme based on the growth pattern of this tumor is proposed to help the surgeon choose a procedure to access this lesion. This report describes the results obtained with the surgical removal of large (class III and IV) nasopharyngeal angiofibromas through the infratemporal fossa approach. Fourteen patients were cured and one individual developed a recurrence which was totally removed at a second procedure. Surgical morbidity was minimal and there was no mortality. Radiation therapy was necessary in only one patient who had tumor infiltration of the cavernous sinus.

Adolescent↗

Management of the internal carotid artery in surgery of the skull base.

Management of the internal carotid artery in skull-base surgery can be a difficult problem when disease involves this vessel or resection is anatomically limited by it. The recent radiologic development of the detachable balloon catheter has permitted occlusion of the internal carotid artery in a controlled setting prior to any surgical procedure. An obvious prerequisite to using this technique is the demonstration of adequate collateral blood flow to the brain. Patients are evaluated with arteriography and temporary arterial balloon occlusion while monitoring physical signs and electroencephalography (EEG). Although usually performed preoperatively, internal carotid artery occlusion is needed intraoperatively on occasion. This essential adjuvant technique for the skull-base surgeon will be detailed along with its indications and limitations in 24 patients.

Carotid Artery, Internal↗

Histology of synthetic ossicular prostheses.

Thirty-three synthetic middle ear prostheses removed after two to 99 months of implantation were examined histologically. All prostheses were infiltrated by fibroblasts, capillaries, collagen fibrils, and multinucleate foreign body giant cells. Although some of the giant cells contained tiny particles of the prosthetic material, there was no evidence of erosion or engulfment of larger particles of the prosthesis or structural dissolution of the prosthesis. New histologic findings were aseptic necrosis and focal calcification in the interior of some of the prostheses.

Ear, Middle↗