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Biomedical subjects

U Fisch

Publications and source records attributed to U Fisch.

193 records · Page 11Linked to original sources
PubMedDate not supplied

Obliteration of the middle ear and mastoid cleft in subtotal petrosectomy: indications, technique, and results.

Lateral surgical approaches to the base of the skull through the temporal bone often result in a large cavity with exposed dura and vascular structures and no possibility of reconstruction of the middle ear conductive hearing mechanism. Subtotal petrosectomy with tympanomastoid obliteration provides a relatively safe and secure closure of the surgical defect in the temporal bone and eliminates the problems associated with an open mastoid cavity. Eradication of all accessible air cell tracts and mucosa in the petrous pyramid, obliteration of the eustachian tubal orifice, closure of the external auditory canal, and fat obliteration of the middle ear and mastoid clefts are essential in the procedure. Over the last 10 years this technique has been utilized in 372 base of skull procedures with a complication rate of less than 5%. Infection occurred only in those cases with draining cavities or contaminated wounds.

Cerebrospinal Fluid Otorrhea↗
PubMedDate not supplied

Adenomas of the temporal bone.

Three cases of primary adenomas of the petrous bone are presented and compared to an adenoma arising from the external ear canal. In contrast to other adenomatous tumors, these caused slowly progressive inner ear symptoms without other signs, hence making differentiation from other benign lesions difficult. In one case, association with von Hippel-Lindau disease is suspected because of a strong family history and recent discovery of a similar lesion in the opposite ear. Bone destruction was found radiographically and clinically with vascular tumor tissue and cysts permeating the bone, causing adjacent bone destruction and remodeling. The histopathologic examination demonstrated this to be a benign process, however, with no direct tumor invasion or other signs of malignancy. Subtotal petrosectomy is a proven approach for complete removal of these tumors. Review of the literature revealed no previous reports of benign adenomas originating in the petrous bone.

Adenoma↗
PubMedDate not supplied

Experimentally induced facial nerve compression in cats.

An experimentally controlled compression of the facial nerve was induced in 32 cats by applying polyethylene tubes of different diameter on its main trunk. The effect of decompression (removal of the compressing tubes) was investigated by clinical evaluation of the eye blinking reflex, by recording the summation potential of the orbicularis oculi muscle and by histological investigation of the nerve specimens. The results obtained demonstrate that even in presence of degenerated nerve fibers, disrupture of the endoneural tubes can be avoided if decompression is performed within 12 days after injury. The release of circumferential pressure over the degenerated facial nerve within the above-mentioned delay is thus beneficial for optimal regeneration. The possible implications of these findings for the treatment of Bell's palsy are discussed.

Animals↗
PubMedDate not supplied

Measurement of oxygen tension in human perilymph.

The oxygen tension of the human perilymph has been determined without complications by using a technique based upon the polarographic principle. Carbon dioxide produced the most marked increase in oxygen tension in the human perilymph. No change in the perilymphatic PO2 was observed after administration of eupaverine and low molecular weight dextran. 5% CO2-95%O2 has been found to be the gas mixture producing the largest increase in oxygen tension in the human perilymph, without side effects. In order to achieve maximal oxygenation of the perilymph, the therapeutic administration of 5% CO2-95% O2 should continue for at least 30 minutes. At this preliminary stage it is not possible to assess the accuracy of the presented technique in determining the presence of a vascular disorder of the inner ear in patients.

Blood Pressure↗
PubMedDate not supplied

Perilymph oxygenation in sudden and progressive sensorineural hearing loss.

The perilymphatic oxygen tension of the vestibular perilymph of 34 patients with different inner ear losses were measured with the polarographic method before and after inhalation with carbogen. Two patterns of disturbed perilymphatic oxygenation were observed: 1) Characterized by low initial values of perilymphatic oxygenation and normal response to carbogen inhalation was present in sudden deafness and sudden cochleovestibular loss of inner ear function. 2) Characterized by normal initial values of perilymphatic oxygenation and a low response to carbogen, was found in presence of a slowly progressive sensorineural hearing loss. The significance of the obtained results in regard to the possible vascular pathology of the inner ear is discussed.

Adult↗
PubMedDate not supplied

On the pathogenesis of Bell's palsy.

The data obtained from the anatomical study of the Fallopian canal, the intraoperative evoked electromyography and the histopathological evaluation of specimens from the greater petrosal nerve support the entrapment neuropathy concept in Bell's palsy.

Adult↗