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Biomedical subjects

U Fagiolo

Publications and source records attributed to U Fagiolo.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

[Nickel-induced allergic contact dermatitis: reactivation by oral administration of hapten].

Recent reports suggest the high frequency of nickel induced allergic contact dermatitis and the absence in some patients of a clinical improvement following topical avoidance of sensitising allergen. In this study we evaluated the role of food ingested nickel in the maintenance and exacerbations of the disease. A high frequency of cutaneous exacerbations was obtained after oral challenge with a low nickel containing diet. These results suggest a pathogenetic role of nickel present in foods and indicate that an appropriate diet may be useful in the prophylaxis and in the therapy of nickel dermatitis in sensitized patients.

Dermatitis, Contact↗
PubMedDate not supplied

Family occurrence and hla system in tumoral calcinosis.

A 35-year-old patient, from a ten sibling family, was eight years old at the first presentation of tumoral calcinosis. Since then, in spite of several surgical excisions, the masses have increased in number and size are to be found in various para-articular areas. One brother and one sister of the patient, of 39 and 45 years respectively, had also had tumoral calcinosis, but recovered completely, on surgical removal of the masses. The HLA system studies carried out in the siblings revealed the HLA A10 BW16 haplotype in nine of them, including the three patients. If confirmed in other cases, our data might indicate that tumoral calcinosis is a disease associated with the HLA system.

Adult↗