Biomedical subjects
Publications and source records attributed to U Erikson.
A new dimeric contrast medium, Ph DZ 59B, was injected into the subarachnoid space in experimental animals. Excellent films were invariably obtained. Ph DZ 59B was well tolerated by dogs and cats and relatively well by monkeys.
The videodensitometer has been used in a group of 20 patients with aortic incompetence and incompetence combined with stenosis. The method appears effective in the preoperative evaluation of the valvular and ventricular function of the patient. It gives objective and probably more accurate information of the regurgitation fraction and the ejection fraction than the commonly used semiquantitative methods. The method is simple to use and needs no technical changes in the roentgen equipment.
A new manufacturing process and new shapes of the left and right catheters for coronary angiography by the transfemoral route increase the safety of the examination by reducing the time and avoiding the risks involved in catheter occlusion of the arteries. The simultaneous filling of the sinus and the whole coronary artery from its origin increases the anatomic information. Pressure-monitoring is unnecessary.
Polymeric, water-soluble, iodine-containing contrast agents have been synthesized and tested in renal angiography and thoracic aortography in rabbits and in femoral arteriography in dogs. Good filling of the arteries and also of the veins was obtained.
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A newly synthesized dimer Ph DZ 59B and Angiografin were used in high doses in renal angiography. The two contrast media appeared to have no clinical effects. Light microscopy shows no changes from the radiogrphic agents in the kidneys removed due to carcinoma.
The PTB-suction prosthesis has been studied by a roentgenological technique. There is complete contact between the skin of the stump and the plastic inner surface of the socket. The movement of the stump in the socket is minimal. The displacement of the skeletal stump is reduced to half in the PTB-suction prosthesis, compared with the strap-suspended PTB prosthesis. As a result, the stability between stump and socket is increased, provided that the stump is sufficiently long. Skin sores are avoided. The prosthesis, when adequately fitted, guarantees a good circulation within the stump and a cosmetically favourable fit with a feeling of walking with "a normal leg".
The effects of carotid artery injections of some roentgen contrast agents on the EEG have been studied in unanesthetised dogs. The results support earlier clinical studies that the new contrast agent Ph DZ59B is suitable in carotid arteriography.
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