Biomedical subjects

U Deichert

Publications and source records attributed to U Deichert.

25 records · Page 2Linked to original sources

PubMed1990

[Preoperative reduction of uterine leiomyoma by the GnRH-analog goserelin (zoladex)].

The administration of GnRH analogues is expected to improve treatment by avoiding hysterectomy, since problems connected with the surgical removal of leiomyomata are correlated with their size. In this study the GnRH analogue goserelin in its depot formulation (Zoladex, ICI, Plankstadt) was used for treating isolated leiomyomata of the uterus. All patients were treated for 3 months before myomectomy was performed. The complete regression of a large myoma (206 cm3) was observed in 1 of 11 patients. In 5 cases a reduction in volume of more than 50% was achieved. Ovarian function was suppressed by goserelin, after a short-term stimulation, within 7 +/- 3 days. Serum levels of 17 beta-oestradiol were found to be generally less than 25 pg/ml. All patients reported climacteric complaints, but in no case had therapy to be discontinued. After cessation of goserelin, restoration of ovarian function was observed in all patients.

Adult↗

PubMed1990

[Transvaginal contrast hysterosalpingo-sonography with the B-image procedure and color-coded duplex sonography for the assessment of fallopian tube patency].

Transvaginal hysterosalpingo-contrast-sonography (HYCOSY), a new method for the direct assessment of tubal patency by means of ultrasonography, was employed in 68 women with infertility problems. In 67 cases, the findings were compared with hysterosal-pinography or chromolaparoscopy, performed either subsequently while the patient was still under the anaesthetic or later. The contrast demonstration of the Fallopian tubes was performed with the B mode procedure in 54 cases (Group 1) and by means of colour-coded duplex sonography in 14 (Group 2). In Group 1, the findings agreed completely in 39 cases, partially in 14 and not at all in one. In Group 2, in which 13 of the 14 cases were compared, the findings were identical in 9 cases and partially in 4. From the point of view of image documentation, the more vivid demonstration of free tubal passage in colour Doppler sonography compared to the simple B mode appears to be an advantage. Further studies are needed to determine whether contrast-perfused but dislocated tubes can be detected more easily and quickly with colour Doppler than in B mode.

Adolescent↗

PubMed1989

Transvaginal hysterosalpingo-contrast-sonography (Hy-Co-Sy) compared with conventional tubal diagnostics.

Transvaginal hysterosalpingo-contrast-sonography (Hy-Co-Sy) is described as a new method for direct imaging of the tubal passage in tubal diagnostics. During one period of anaesthesia, a transvaginal Hy-Co-Sy was followed by either hysterosalpingography or chromolaparoscopy in 42 patients with sterility disorders. The contrast-enhanced sonography of the tubes was performed in eight cases with sterile saline solution (group 1) and 34 cases with a specially developed ultrasound contrast medium (SH U 454, group 2). The findings obtained by transvaginal Hy-Co-Sy were compared with those of the conventional method. By both methods, there was complete agreement with respect to the same evaluation of tubal passage for both sides, partial agreement when firstly the tubes were assessed as unilaterally or bilaterally open--without precise localization of the side--depending on the appearance of fluid in the pouch of Douglas, or secondly, only one side, when compared, showed agreement. In group 1 complete agreement was found once, partial agreement five times and non-agreement twice, while in group 2 complete agreement was found 22 times (65%), partial agreement 11 times and non-agreement once.

Adult↗

PubMed1988

[Transvaginal contrast hysterosonography. A new diagnostic procedure for the differentiation of intrauterine and myometrial findings].

In 30 patients with sterility problems, menstrual irregularities, and/or suspected tumor the uterine wall was evaluated by transvaginal hystero-contrast-sonography (CoSy). These findings were compared with those of hysterosalpingography (HSG) or chromo-laparoscopy which were done during the same anesthesia. In 6 patients there was no coincidence, and additional information of relevance could be achieved by the other procedure. One case of submucous and an other of intramural fibroid were exactly differentiated by the transvaginal CoSy. This was not possible by the HSG. In addition two large intramural fibroids were exactly localized by CoSy, where as this couldn't be demonstrated endoscopically. Two uteri arcuati have not been seen by CoSy, but were recognized by HSG. So we recommend the transvaginal CoSy of the uterus as a pretherapeutic procedure for the differentiation and localization of intracavital and myometrial findings. At least at moment it seems to be that the image of light uterine malformations could be better demonstrated by conventional diagnostic methods.

Adult↗

PubMed1987

[The corpus luteum in the ultrasound image and its endocrine function].

The corpora lutea of 38 patients with sterility problems were sonographically measured. In a total of 51 cycles the corpus luteum values were compared with the estradiol (E2) and progesterone (P) plasma levels on the day of sonographic examination (SE). In 49 SEs performed immediately following ovulation the corpus luteum was cystic in 26 cases (means = 14.9 mm) and solid in 23 cases (means = 12.8 mm, p less than 0.05). The postovulatory differences between the corresponding E2 and P values, respectively, were not significant. In the midluteal phase the corpora lutea were cystic in 22 cases (means = 18.2 mm) and solid in 14 (means = 13.4 mm, p less than 0.001). Both E2 (means = 362.8 pg/ml) as well as P (means = 27.7 ng/ml) were higher in the women with cystic than in those with solid corpora lutea (E2 means = 222 pg/ml; P means = 19.4 ng/ml; p less than 0.01 in each case). When the patient collective was split into two groups, with and without stimulation therapy, a significantly higher E2 was only found in the "with therapy" group in patients with cystic corpus luteum in the midluteal phase. The size of the midluteal corpus luteum correlated in particular with the E2 plasma concentrations in all patients (p less than 0.005). Thus, in addition to sonographic measurement of the endometrium, sonographic demonstration of the corpus luteum is also useful in assessing the luteal phase.

Corpus Luteum↗

PubMed1987

[Scleroderma in pregnancy].

The case of a 23-year-old patient with scleroderma in her first pregnancy is described. The problem complexes, the influence of the disease on the continuation of pregnancy, and how the pregnancy affects the prognosis of the scleroderma are discussed and compared with the global literature. It does not appear possible to prove that scleroderma has a specifically deleterious effect on mother and child during pregnancy. Nor does a pregnancy definitely have a positive or negative effect on the subsequent course of a scleroderma.

Adult↗

PubMed1986

The sonographic and endocrinologic evaluation of the endometrium in the luteal phase.

Follicular development and the endometrial thickness were determined sonographically in 19 outpatients with different causes of sterility, treated during natural or stimulated cycles. The estimates of the endometrial thickness, assessed by ultrasound in the mid-luteal phase, and the levels of 17 beta-oestradiol and progesterone in the same patients sampled on the day of sonography were compared. Five patients became pregnant (group 1) and showed good progesterone values. Eight patients who were not pregnant showed progesterone values above 15 ng/ml in the mid-luteal phase (group 2). The progesterone values of group 3 were below 15 ng/ml by definition. The mean endometrial thickness in group 1 (means = 11.3 mm) and group 2 (means = 11.8 mm) were significantly higher than that of group 3 (means = 8.3 mm). The sonographic measurement of the mid-luteal endometrium thickness serves as an additional criterion for the evaluation of the secretory phase of the menstrual cycle.

Adult↗