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Biomedical subjects

U Ambanelli

Publications and source records attributed to U Ambanelli.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

Association between DR3 and thrombocytopenia due to gold or tiopronin. Case reports and review of the literature.

Two patients who developed thrombocytopenia while on Tiopronin and gold salts respectively were HLA typed. Their common haplotype was A25(10), B8, DR3. A survey of the literature showed that the association between DR3 and the sudden onset form of thrombocytopenia is striking. A genetic predisposition, besides other unknown factors, seems to play a crucial role.

Amino Acids, Sulfur↗
PubMedDate not supplied

Serum and synovial fluid concentrations of alpha2 macroglobulin and alpha2 neuroamino-glycoprotein in rheumatoid arthritis.

The serum and synovial fluid concentrations of alpha2 macroglobulin and alpha2 neuramino glycoprotein of patients with rheumatoid arthritis have been studied. For, both protein fractions have antiprotease activity and inhibit, though to different degrees, many factors concerning inflammation. Even though both fractions have certain activities in common, in rheumatoid arthritis, we neither see a parallel increase nor antagonistic actions in the case of alpha2 macroglobulin and alpha2 neuramino-glycoprotein.

Adult↗
PubMedDate not supplied

Clinical features, scintiscan characteristics and X-ray progression of late onset rheumatoid arthritis.

The clinical features, serology behaviour, scintiscan characteristics and the degree of X-ray progression according to the disease duration were compared in two RA groups with a disease onset after 65 years of age (LORA) and before 65 (EORA) respectively. No differences emerged in either the clinical findings or in the scintiscan picture. A sub-group of LORA showed acute flares of the illness presenting with very high ESR values and high fever. The erosive index (EI) evaluated in three areas (carpal-bone and wrist, MCP and PIP joints) revealed an undistinguishable degree of X-ray damage either in seropositive or seronegative patients, whereas seropositive EORA fared clearly worse than seronegative ones. A prospective study in two small sub-groups of LORA and EORA revealed a progression of X-ray erosions despite second line drug treatment in both groups, especially in LORA.

Adult↗