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Tosiaki Miyati

Publications and source records attributed to Tosiaki Miyati.

13 recordsLinked to original sources
PubMed2006

[Optimization of three-dimensional triple IR fast spoiled gradient recalled acquisition in the steady state (FSPGR) to decrease vascular artifact at 3.0 Tesla].

The purpose of this study was to decrease vascular artifacts caused by the in-flow effect in three-dimensional inversion recovery prepared fast spoiled gradient recalled acquisition in the steady state (3D IR FSPGR) at 3.0 Tesla. We developed 3D triple IR (3IR) FSPGR and examined the signal characteristics of the new sequence. We have optimized scan parameters based on simulation, phantom, and in-vivo studies. As a result, optimized parameters (1st TI=600 ms, 3rd TI=500 ms) successfully have produced the vessel signal at more than 40% reduction, while gray-white matter contrast was preserved. Moreover, the reduced artifact was also confirmed by visual inspection of the in-vivo images for which this condition was used. Thus, 3D 3IR FSPGR was a useful sequence for the acquisition of T1-weighted images at 3.0 Tesla.

Adult↗
PubMed2006

[Vessel contrast and saturation effect at three Tesla in three-dimensional time of flight magnetic resonance angiography].

The purpose of this study was to clarify the effects of the increased field strength of 1.5T vs. 3.0T on blood vessel contrast and saturation in 3D time of flight MR angiography. Vessel contrast and saturation effect were evaluated for various flow velocities and flip angles using a steady-state flow phantom. The results showed increased vessel contrast and decreased saturation of blood on 3.0T compared to 1.5T, due to the following factors: 1) sufficient saturation of stationary tissue by extended T1 relaxation time, 2) increased signal-to-noise ratio (SNR), and 3) high in-flow effect. However, the blood signal on 3.0T revealed a strong tendency to phase dispersion compared to that of 1.5T. Therefore, in order to exploit the characteristic of high field strength in 3.0T, it is suggested that adequate consideration of these factors is important in setting the image acquisition parameters.

Imaging, Three-Dimensional↗
PubMed2006

[Performance evaluation of computed tomography with equivalent resolution images].

A method of evaluating the performance of computed tomography (CT) with equivalent resolution images was investigated. Generally, in performance evaluations of CT, the resolution property is measured by the wire method, and the noise property is measured from noise images of a cylindrical water phantom. The signal-to-noise ratio (SNR) is then calculated for the integrated evaluation. Our proposed method enabled perceptual integrated evaluation by using equivalent resolution images created with frequency processing. The frequency-processing factor was calculated from the ratio of the modulation transfer factors of two models of CT, and the image of one of the two was processed by the factor. Because these processed images have resolution equivalent to images of the other CT, the perceptual evaluation with noise images becomes effective. In this investigation, images of a water phantom and a middle contrast resolution phantom were employed. Perceptual comparison of the amount of noise with equivalent resolution images could be performed easily, and effective performance evaluation was achieved. Therefore, our proposed method is useful for noise property and performance evaluation of CT.

Evaluation Studies as Topic↗
PubMed2006

Evaluation of CH3-DTPA-Gd (NMS60) as a new MR contrast agent: early phase II study in brain tumors and dual dynamic contrast-enhanced imaging.

PURPOSE: A newly developed contrast material, CH3-DTPA-Gd (NMS60), a trimer containing 3 Gd(3+) atoms per molecule, has been shown to offer greater enhancement and longer vascular retention than gadopentetate dimeglumine (Gd-DTPA) in animals. We report on our early phase II study on NMS60 in brain tumor patients together with supplementary investigations. METHODS AND MATERIALS: The longitudinal relaxation rate (R(1)=1/T(1)) and the transverse relaxation rate (R(2)*=1/T(2)*) of NMS60 and Gd-DTPA were determined at 20 degrees C in water at 1.5 T. An NMS60 dose of 0.1 or 0.2 mmol (Gd)/kg was randomly assigned and administered to 10 patients (five women, five men; mean age: 49 years) with brain tumors. Safety and contrast-enhancing ability of NMS60 were evaluated. Dual dynamic contrast-enhanced T(1) and R(2)* studies (DUCE imaging) were also carried out in two patients. RESULTS: Regarding the relaxivity per Gd, R(1) and R(2)* of NMS60 were 9.5 and 11.0 (mmol/L x s)(-1), respectively, compared to 4.8 and 7.2 (mmol/L x s)(-1) for Gd-DTPA. Although a transient slight increase of alanine aminotransferase was observed in one case, no other adverse reactions were observed after administration of NMS60. Contrast enhancement by NMS60 was excellent at both concentrations, and when tumor detectability was assessed with a five-point scale, the diagnostic usefulness was 4 or higher in all cases. In DUCE imaging, NMS60 appeared to show high signal intensity, when compared with the data obtained separately for Gd-DTPA. CONCLUSION: NMS60 had a high contrasting effect and little toxicity, and is expected to be clinically useful.

Brain↗
PubMed2006

[MRI-intracranial compliance analysis in patients with NPH].

We devised a method for non-invasively assessing intracranial compliance with retrospective ECG-triggered phase contrast cine MRI. This method was examined in patients with normal pressure hydrocephalus (NPH) group and those with asymptomatic ventricular dilation or brain atrophy (VD group), and in healthy volunteers (control group). Intracranial volume change (DeltaV(max)) was calculated from arterial inflow, venous outflow, cerebrospinal fluid (CSF) flow, and spinal cord motion at the C2 level during a cardiac cycle. Next, craniospinal CSF pressure gradient change (DeltaPG(max)) was calculated from measured CSF flow velocity using a simplified Navier-Stokes equation. Finally, Ci was obtained by dividing Delta V(max) into DeltaPG(max). Ci in the NPH group was significantly smaller and could be differentiated from other groups. This method makes it possible to non-invasively obtain a more detailed determination of the intracranial state and dynamics in NPH and to assist in its diagnosis.

Adolescent↗
PubMed2006

An experimental comparison of flat-panel detector performance for direct and indirect systems (initial experiences and physical evaluation).

The purpose of this work was to compare direct and indirect detectors in terms of their system linearity, presampled modulation transfer function (MTF), Wiener spectrum (WS), noise equivalent quanta (NEQ), and power spectrum. Measurements were made on two flat-panel detectors, GE Revolution XR/d (indirect) and Shimadzu Safire (direct) radiographic techniques. The system linearity of the systems was measured using a time-scale method. The MTF of the systems was measured using an edge method. The WS of the systems was determined for a variable range of exposure levels by two-dimensional Fourier analysis. The NEQ was assessed from the measured MTF, WS, and estimated ideal signal-to-noise ratios. Power spectrum analyzed the chest phantom within artificial lesions. System linearity was excellent for the direct systems. For the direct system, the MTF was found to be significantly higher than that for the indirect systems. For the direct system, the WS was relatively uniform across all frequencies. In comparison, the indirect system exhibited a drop in the WS at high frequencies. At lower frequencies, the NEQ for the indirect system was noticeably higher than for the direct system. Power spectrum for the direct system was relatively flat and similar to that for white noise. The indirect system exhibited significant reduction at high spatial frequencies. In general, the direct systems exhibit improved image quality over indirect systems at comparable exposure dose.

Computer Terminals↗
PubMed2003

[MRI safety].

Explore the source record for details and available documents.

Electromagnetic Fields↗
PubMed2002

Frequency analyses of CSF flow on cine MRI in normal pressure hydrocephalus.

Our objective was to clarify intracranial cerebrospinal fluid (CSF) flow dynamics in normal-pressure hydrocephalus (NPH). Frequency analyses of CSF flow measured with phase-contrast cine MRI were performed. The CSF flow spectra in the aqueduct were determined in patients ( n=51) with NPH, brain atrophy or asymptomatic ventricular dilation (VD), and in healthy volunteers (control group; n=25). The changes in CSF flow spectra were also analyzed after intravenous injection of acetazolamide. Moreover, a phase transfer function (PTF) calculated from the spectra of the driving vascular pulsation and CSF flow in the aqueduct were assessed. These values were compared with the pressure volume response (PVR). The amplitude in the NPH group was significantly larger than that in the VD or control group because of a decrease in compliance. The phase in the NPH group was significantly different from that in either the VD or the control group, but no difference was found between the VD and control groups. The amplitude increased in all groups after acetazolamide injection. The PTF in the NPH group was significantly larger than in the control group, and a positive correlation was noted between PTF and PVR. Frequency analyses of CSF flow measured by cine MRI make it possible to noninvasively obtain a more detailed picture of the pathophysiology of NPH.

Acetazolamide↗
PubMed2002

Measurements of MTF and SNR(f) using a subtraction method in MRI.

A method was developed for accurate measurement of the modulation transfer function (MTF) and signal-to-noise ratio in the spatial frequency domain (SNR(f)) of magnetic resonance images (MRI). The MTF was calculated from the complex images of a line object which were obtained by the subtraction of two separately acquired data sets of a specially designed phantom with a sliding sheet. Moreover, the SNR(f) was calculated from the MTF and Wiener spectrum, both of which were determined using the same phantom configuration. The MTFs and SNR(f)s in the conventional spin-echo (SE) and turbo SE, in which the effective echo time was set to the first echo, were evaluated by changing the T2 of the phantom and the echo train length. The MTFs in the positive and negative frequencies indicated the effect of the k-space trajectory for each pulse sequence. SNR(f)s gave spatial frequency information that was not obtained with conventional methods. In this method, the influence of image nonuniformity and unwanted artefacts (edge and ghost) could be eliminated. An analysis of the MTF and the SNR in the spatial frequency domain provides additional information for the assessment of image quality in MRI.

Artifacts↗
PubMed2002

[New method of measuring presampling MTF by fourier transform of square-wave chart image].

We developed an easy method of measuring the presampling modulation transfer function (MTF) using the square wave chart in digital radiography. In this method, the presampling MTF is measured by Fourier transform of image data of the square wave chart. When Fourier analysis of the sampling data of a square wave is carried out, it is generally difficult to find the starting point and terminal point of the periodic data that should be extracted because of an insufficient number of data. To solve this problem, interpolated data were calculated by using a window function of the frequency domain. The aliasing error was avoided using a characteristic such that the square wave has discrete frequency components. The accuracy of this method was investigated by computer simulation study. Actual measurement of the presampling MTF by this method was also performed with a CR system. These studies indicated the effectiveness of our proposed method in terms of accuracy and ease of use.

Computer Simulation↗