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Tie-jun Wu

Publications and source records attributed to Tie-jun Wu.

5 recordsLinked to original sources
PubMed2006

[Effect of total parenteral nutrition with supplementation of glutamine on the plasma diamine oxidase activity and D-lactate content in patients with multiple organ dysfunction syndrome].

OBJECTIVE: To explore the effect of total parenteral nutrition (TPN) supplemented with glutamine on the activity of plasma diamine oxidase (DAO) and D-lactate content in blood of patients with multiple organ dysfunction syndrome (MODS). METHODS: Forty patients with MODS in the intensive care unit (ICU) from September 2003 to June 2005 were involved in a randomized controlled study, and divided into routine group (group A, n=20), the glutamine +TPN treatment group (group B, n=20). All patients received equivalent nitrogen and caloric values in parenteral nutrition. Group A was given routine TPN, and group B was given extra glutamine 0.27 g.kg(-1).d(-1) (i. e. dipeptiven 0.4 g.kg(-1).d(-1)) for 7 days. The activity of plasma DAO and D-lactate content, the treatment time and the mortality rate of the two groups were determined before TPN, on the 1st, the 3rd and the 7th day after TPN. At the same time, 20 healthy blood donors formed the healthy control group (group C). All the data were analyzed with the SPSS 10.0 software. RESULTS: Before treatment, the activity of plasma DAO and D-lactate content of the two patient groups were significantly higher than those of group C (both P<0.01), and there was no difference between group A and group B (P>0.05). After the treatment of glutamine supplemented TPN, the activity of plasma DAO and D-lactate content of group B were lower than those of group A (both P<0.01). The duration of TPN was (15.8+/-2.3) days for group A and (12.5+/-2.4) days for group B. The former was significantly longer than that of group B (P<0.05). The mortality rate of group A was 25%, the mortality rate of group B was 10%, but there was no significant difference between the two groups (P>0.05). CONCLUSION: The glutamine (dipeptiven) supplementation through vein can help increase the supply of energy substrate to intestinal mucosa epithelium, and decrease the activity of plasma DAO and D-lactate content. It has an important effect on protecting the intestinal mucosa epithelial function. It also helps shorten the TPN treatment course.

Adult↗
PubMed2004

[Clinical study of cerebral oxygen utilization coefficients in patients with severe head injury].

OBJECTIVE: To investigate the relationship in cerebral oxygen utilization coefficients (O.2UCc) in patients with acute severe head injury and illness prognosis. METHODS: Forty patients with acute severe head injury were studied, and 40 patients with light head injury were used as control. Through blood analysis, the changes in oxygen saturation of carotid blood (SaO(2)), oxygen saturation of jugular blood (SjO(2)), cerebral arteriovenous difference of oxygen saturation (S(a-j)O(2)), O.2 UCc were observed. Furthermore, the relationship of these patients' condition and prognosis was analyzed. RESULTS: There was no significant change between the test group and control group in SaO(2). In test group, SjO(2) increased and O.2 UCc decreased, there was an obvious difference between two groups (both P<0.01). In test group, 26 died and 14 lived. There was no significant difference between died and lived patients in SaO(2). SjO(2) significantly increased and O.2 UCc obviously decreased in died patients in comparison with those of the lived patients (both P<0.01). CONCLUSION: Cerebral oxygen metabolism dynamics obstacle frequently was accompanied with acute severe head injury. The high SjO(2) and low O.2 UCc are main symptoms with O.2 UCc<11percent hinting a bad prognosis.

Adult↗
PubMed2004

[Clinical analysis of the factors related to diarrhea in intensive care unit].

OBJECTIVE: To assess the causative factors of diarrhea in intensive care unit(ICU) patients for the purpose of providing a scientific basis for the treatment regime. METHODS: The factors related to diarrhea in patients in the ICU of Liaocheng People's Hospital were studied by analyzing the features of 86 patients who developed diarrhea among 735 patients admitted in 2 years (from January 2001 to December 2002). RESULTS: Among the total of 86 patients(11.70%) who had developed diarrhea, 51 had received enteral nutrition improperly, accounting for 59.30%; 18 patients had suffered from intestinal tract infection, accounting for 20.93%. In 15 patients diarrhea occurred after the administration of broad-spectrum antibiotics, accounting for 17.44%. In 11 patients it was due to the use of drugs which enhanced motility of gastrointestinal tract, and this accounted for 12.79%. Finally, in 5 patients, diarrhea was thought to be related to the mechanical ventilation, and it accounted for 5.81%. The mean age of the patients was (57.71+/-13.40) years, the average acute physiology and chronic health evaluation (APACHE II) was (21.51+/-4.90)scores, and the mean length of staying in the ICU was (8.0+/-1.2) days, which was longer than that of patients without the complication of diarrhea ((51.20+/-11.31)years, (12.01+/-1.20) scores, (4.0+/-1.0) days respectively, all P<0.01). The pathogenic factors related to diarrhea complicating ICU patients seemed to be different from that in other patients. CONCLUSION: The causative factors of diarrhea in ICU patients appear to be different from that in other patients, and special attention should be given in order to avoid it.

Adolescent↗
PubMedDate not supplied

An adaptive ant colony system algorithm for continuous-space optimization problems.

Ant colony algorithms comprise a novel category of evolutionary computation methods for optimization problems, especially for sequencing-type combinatorial optimization problems. An adaptive ant colony algorithm is proposed in this paper to tackle continuous-space optimization problems, using a new objective-function-based heuristic pheromone assignment approach for pheromone update to filtrate solution candidates. Global optimal solutions can be reached more rapidly by self-adjusting the path searching behaviors of the ants according to objective values. The performance of the proposed algorithm is compared with a basic ant colony algorithm and a Square Quadratic Programming approach in solving two benchmark problems with multiple extremes. The results indicated that the efficiency and reliability of the proposed algorithm were greatly improved.

Algorithms↗