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Teruki Sone

Publications and source records attributed to Teruki Sone.

28 records · Page 2Linked to original sources
PubMed2003

T2-weighted MR imaging of prostate cancer: multishot echo-planar imaging vs fast spin-echo imaging.

The aim of the present study was to assess the performance of pre-biopsy T2-weighted MR imaging using multishot echo-planar imaging (EPI) sequence for visualization of prostate cancer and to compare image quality with that of fast spin-echo (FSE) sequence. Thirty-nine patients with suspected prostate cancer and one healthy male volunteer were examined on a 1.5-T MR scanner equipped with a pelvic phased-array coil. Axial MR images were obtained using multishot EPI sequence with a multishot number of 16 and FSE sequence without fat suppression. Paired EPI and FSE images were independently evaluated by three radiologists. Furthermore, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were compared between EPI and FSE images of 12 pathologically proven lesions of prostate cancer. Delineation of the periprostatic venous plexus, prostate zonal anatomy, and seminal vesicle on EPI was graded to be superior/inferior to FSE in 15.8/0, 14.6/0, and 21.5/4.3% of cases, respectively. On the other hand, delineation of the neurovascular bundle was superior/inferior to FSE in 2.6/13.2% of cases. The SNR and CNR of prostate cancer on EPI were significantly higher than those on FSE (7.99 +/- 2.51 vs 3.36 +/- 0.58, p<0.0001, and 5.51 +/- 2.02 vs 2.21 +/- 0.79, p<0.0001, respectively). In conclusion, multishot EPI has higher quality of contrast resolution for imaging of prostate cancer compared with FSE and would have the potential usefulness in the detection of prostate cancer, although these results obtained with a phased-array coil cannot be extrapolated to examinations performed with an endorectal coil.

Aged↗
PubMed2003

[Methodology of bone mass measurement].

Over the last several decades, methodologies for the assessment of bone mineral density have considerably progressed and at present bone densitometry has become a prerequisite for diagnosis, monitoring, and epidemiological studies of osteoporosis. However, until recently it was difficult to monitor the response to therapy by bone mineral measurement since the change of bone mineral density by therapy was small compared with measurement errors. On the other hand, bisphosphonate such as risedronate and alendronate have a strong effect on bone mineral density and bone densitometry would be expected to be used more widely in the evaluation of their therapeutic effect. In this paper, bone mass measurement clinically used at present is outlined.

Bone Density↗
PubMed2003

[Bone mass measurement and its evaluation: their usefulness and problem].

In this paper, bone mass measurement and its evaluation have been reviewed. The bone lesions in renal osteodystrophy are classified into high- and low turnover, and the decreased rate of bone mineral density (BMD) might be different in osteitis fibrosa and adynamic bone disease. Secondary hyperparathyroid patients showed lower BMD values in mainly composed of the cortical bone than those in mainly composed of the trabecular bone.

English Abstract↗
PubMed2003

[Therapeutic approaches to increased bone resorption].

The accelerated bone resorption contributes significantly to the pathophysiology of diseases such as osteoporosis, Paget's disease, hypercalcemia, bone metastasis, and inflammation of bone associated with rheumatoid arthritis. Several antiresorptive agents have been validated as a means to control bone resorption in these diseases. A recent understanding of the molecular mechanism of osteoclastic bone resorption is providing opportunities for developing novel antiresorptive agents.

English Abstract↗
PubMed2003

[Diagnosis of male osteoporosis].

Male osteoporosis is not rare because of the recent increase of elderly population. The diagnosis of male osteoporosis is based on BMD as well as in women. Although most of the cross-sectional studies have suggested that men fracture at higher BMD than women, recent prospective longitudinal studies show that the fracture risk increases as BMD decreases in men in the same way as that described in women. However, because of the different BMD distribution, the average BMD in men who fracture is higher than in women and to capture the same proportion of fractures in men, the cutoff BMD value needs to be higher than in women.

English Abstract↗
PubMed2003

[Guideline for diagnosis and therapy of osteoporosis from a point of view of sex difference].

Osteoporosis occurs more common in women than that in men. In addition, there exist the sex differences in bone indexes such as bone mineral density (BMD), bone mineral content, and bone area or width, and in the decreased pattern of BMD associated with aging. Therefore, it is necessary to use a cut-off value of BMD of not women but men, as diagnostic criteria for male osteoporosis. In this article, from a point of view of sex difference, diagnosis and treatment of osteoporosis will be reviewed.

English Abstract↗
PubMed2002

[Techniques for the assessment of bone microstructure].

Recent advances in non-destructive techniques for imaging of cancellous bone have made possible true three-dimensional (3D) quantification of trabecular architecture. The architectural property can be measured from 3D reconstruction of cancellous bone specimens. Examples of such procedures are model-independent assessment of trabecular dimensions, 3D connectivity estimation, degree of anisotropy and structure type assessment. These new techniques would be utilized for the analysis of bone microstructure in various pathophysiological models.

English Abstract↗