Biomedical subjects
Publications and source records attributed to Takeshi Kuramochi.
By introducing an intercalator through D-threoninol to the 10-23 DNAzyme at the junction between its catalytic loop and the binding arm, the RNA cleavage activity was greatly improved.
Between the enactment of Japan's "Organ Transplantation Law" (OTL) in 1997 and the end of October 2003, there were 27 (30 now) legal declarations of brain death, and organs were donated from 26 (29) of those. During this period, four applications for human rights relief were made against organ donation facilities by Takayoshi Okamoto and others. One of these remains under investigation, but the Japanese Federation of Bar Associations (JFBA) has offered recommendations relating to the other three. The purpose of this report lies in examining these applications and recommendations.
If we abide by the dead donor rule, we have to comply with the rule that an organ donor must be declared to be irreversibly and unequivocally dead and not merely dying before the commencement of organ extraction. In this paper, I will show the following: that living donor transplantations violate the dead donor rule; that we cannot say that not only all the brain dead patients (HBDs) but also all the cardiac arrest patients (NHBDs) have been irreversibly and univocally dead at the time of organ extraction; and that we do not know how to tell living potential donors from dead potential donors.