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Biomedical subjects

T Yuri

Publications and source records attributed to T Yuri.

36 records · Page 2Linked to original sources
PubMed1987

[A study on the immunologic effects in workers exposed to low levels of toluene-diisocyanate (TDI)].

Forty-three workers exposed to low levels of toluene diisocyanate (TDI) during the process of producing polyurethane forms were examined immunologically for IgG, A, M, and E and serum enzyme activities such as serum angiotensin converting enzyme (SACE), serum lysozyme (SLZM) and glycylproline dipeptidyl aminopeptidase (GP-DAP). Air concentration of TDI was annually measured in various places of work during the past five years from 1979 to 1983. The results obtained in the present study were as follows. 1. The air concentration of TDI at all places of work was below the permissible concentration level of 0.02 ppm throughout the study period. 2. Subjective symptoms and abnormal findings on chest X-ray considered directly related to TDI exposure were not observed. 3. No remarkable abnormal findings in blood cell counts and in serum biochemical studies could be seen in any of the workers. 4. The serum IgG levels in workers directly exposed to TDI were significantly higher (p less than 0.05) than those in workers indirectly exposed to TDI and in non-exposed workers. 5. In the study of serum enzymatic activity, SLZM activity in workers exposed directly to TDI was significantly higher (p less than 0.01) than those in workers indirectly exposed to TDI and in non-exposed workers.

Adult↗
PubMed1985

Persistent wedge-shaped contrast enhancement of the kidney.

A case with a single wedge-shaped high-density area of the kidney that persists after urography was observed by CT scan. This might be an aberrant form of acute renal failure with multiple wedge-shaped contrast enhancement.

Acute Kidney Injury↗
PubMed1984

'Decubitus' of renal graft on psoas muscle. Local changes of cortical thickness and function in the graft.

Using computerized tomography (CT scan), it was demonstrated that the renal cortex of the graft was thinner in the contact area with the psoas muscle than in the rest of the kidney and that its function in the local area appeared somewhat decreased. These findings might be related to the importance of the perirenal fat in shielding the kidney from mechanical pressure.

Adipose Tissue↗
PubMed1981

Accessible plasma exchange using membrane filter - a successfully treated case of TTP with repeated plasma exchanges.

Plasma exchanges with a hollow-fiber type plasma filter were attempted in a variety of diseases. The unit was easily assembled and the procedures were safely carried out by our dialysis personnel after some instruction. Approximately 2 liters of fresh frozen plasma were used during each plasma exchange and about the same amount of plasma was removed from the patient in 1.5 to 2 hours. This resulted in 66% replacement of patient's albumin on one occasion. Fifty-four plasma exchanges were done in seven patients. The procedure was well tolerated by all patients with only occasional muscle cramps or itching, which were treated with calcium gluconate infusion or antihistamines, respectively. A successfully treated case of TTP in which we used repeated membrane plasma exchanges combined with conventional treatment is also reported.

Adult↗
PubMed1980

Development of acquired cystic disease and adenocarcinoma of the kidney in glomerulonephritic chronic hemodialysis patients.

The fate of the contracted kidney in long-term hemodialysis patients was examined. Total kidney volume was measured by computer assisted tomography in 96 chronically hemodialyzed patients with chronic renal failure due to chronic glomerulonephritis. The presence of cysts and/or tumor in the renal parenchyma was evaluated. Kidney volume decreased progressively up to 3 years after the start of dialysis. However, after 4 years of dialysis, it then increased in a number of cases. Multiple cysts were found in 43.5% of patients on dialysis for less than 3 years and in 79.3% of patients who had been on dialysis for more than 3 years. They were found in 100% of those whose total kidney volume exceeded 50 ml despite more than 3 years dialysis. Bilateral nephrectomy was performed in 4 cases who had been dialyzed for more than 5 years and all showed acquired cystic disease of the kidney. Three out of 4 resected cases had adenocarcinoma and multiple adenomas in addition to acquired cystic disease of the kidneys. The other had intracystic epithelial hyperplasia. These results suggest that long-term hemodialysis is associated with a very high incidence of acquired cystic disease of the kidney. There is frequent enlargement of the contracted kidney, and a high incidence of renal adenocarcinoma in patients with glomerulonephritis leading to treatment with hemodialysis.

Adenocarcinoma↗
PubMed1978

Microangiographic evaluation of the effects of heparin on progressive Masugi nephritis.

Unilateral progressive Masugi nephritis was produced in rabbits and studied by microangiography as well as light and immunofluorescence microscopy. The following five groups were studied: Group 1. Heparin was started simultaneously with nephrotoxic serum (NTS) and was given for one week. The animals were then sacrificed along with the untreated controls. Group 2. This was the same protocol as in group 1 but with three weeks' heparin. Group 3. Heparin was started one day after NTS was given for three weeks. Group 4. Heparin was started one to two weeks after NTS and was given for three weeks. Group 5: late effect group. Heparin was started simultaneously with NTS, was given for four weeks, and the animals were then sacrificed 10 to 13 weeks later. Heparin dose was 5,000 U, s.c., per day in all treated groups. The number of glomeruli seen per unit of cortex by microangiography was significantly increased in the first through the third groups, as compared to the controls. Group 1 did not show this increase but there was some decrease of immunofluorescent fibrinogen. The late effect group (group 5) showed no modification by the treatment, suggesting that an initial improvement may have been negated by persistent immunologic insults after heparin withdrawal.

Angiography↗
PubMedDate not supplied

Dynamic computed tomography in acute renal failure: analysis of time-density curve.

An analysis of dynamic CT curves in 12 patients with acute renal failure was performed. An oliguric patient who demonstrates corticomedullary differentiation on CT images will develop diuresis within 4 days. A corticoaortic junction time of more than 180 s associated with no differentiation between cortex and medulla is associated with prolonged oligoanuria. Impending diuresis is heralded by a corticoaortic junction time of less than 180 s. These preliminary results suggest that an analysis of dynamic CT curves in acute renal failure can predict the time of appearance of the diuretic stage.

Acute Kidney Injury↗
PubMedDate not supplied

Regression of acquired cystic disease of the kidney after successful renal transplantation.

The effect of renal transplantation on acquired cystic disease of the kidney in patients who have been on hemodialysis for more than 5 years was examined in 7 cases by computer-assisted tomography (CT scan). Almost all acquired cysts disappeared, and the size of the original kidneys decreased remarkably in 2 cases 8--10 months after transplantation. 3 other patients, in whom CT scans were performed only after transplantation, showed contracted scarred kidneys with few or no cysts. The involution of acquired cysts was incomplete in 1 case, in whom the cysts persisted for 3 years and 2 months, despite normal renal function. The last case, who was off hemodialysis only for 4 months, exhibited enlargement of the original kidneys and an increase in the number of cysts. These results suggest that a significant number of acquired renal cysts in dialyzed patients with end-stage kidney disease regress rapidly after successful renal transplantation, but this is not always so.

Adult↗