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Biomedical subjects

T Yamura

Publications and source records attributed to T Yamura.

At least 37 records · Page 2Linked to original sources
PubMed1978

Plasma-kinin-forming enzyme in human skin: extraction and column chromatographic separation of plasma-kinin-forming enzyme and its inhibitor.

The optimal salt concentration for extraction of plasma-kinin-forming enzyme from the human skin was investigated. It was confirmed that a salt concentration higher than 1.5 M in the extraction buffer was required for optimal extraction of this enzyme. An inhibitor of this enzyme was detected in the extract with buffer alone, and the coexistence of this enzyme with the inhibitor in buffer extract was also confirmed by using G-200 gel chromatography.

Bradykinin↗
PubMed1978

[Urticaria].

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Histamine Release↗
PubMed1977

A case of eosinophilic lymphfolliculosis of the skin (Kimura's disease).

Eosinophilic lymphfolliculosis of the skin (Kimura's disease) in a 31-year-old male is reported. He had two subcutaneous tumors, 10 x 9 x 3 cm and 9 x 7 x 2 cm in size, in the right retroauricular and submaxillary areas respectively. Histopathologic examination of the tumors showed marked infiltration of eosinophils, mast cells and lymphocytes, and angiomatous proliferation of blood vessels from the dermis to the skeletal muscular tissue. In subcutaneous adipose tissue, there were numerous lymphfollicles with germinal centers in which IgE deposition with reticular appearance was observed by immunofluorescent technique. Study of the peripheral blood showed marked eosinophilia and an increase of serum IgE level. These findings suggest the possibility that Type 1 allergic reaction may be involved in the histogenesis of eosinophilic lymphfolliculosis of the skin, although there is no direct evidence for the existence of antigens which react to IgE antibody in the skin lesion.

Adult↗
PubMed1977

Prevention of plasmin autodigestion by human plasma alpha2-macroglobulin.

The autodigestion of plasmin in neutral solution at 37 degrees C and prevention of plasmin autodigestion by methylamine were confirmed by using rho-Tosyl-L-Arginine-Methyl ester as a substrate of plasmin. The autodigestion of plasmin was prevented by human plasma alpha2-macroglobulin which has been reported as an antiplasmin of immediate and reversible type but was not prevented by alpha1-antitrypsin which has been reported as an antiplasmin of slow and irreversible type.

Fibrinolysin↗
PubMed1976

Release of chymotrypsin-like esterase from isolated rat peritoneal mast cells by arginine-rich calf thymus histone.

Release of chymotrypsin-like esterase from isolated rat peritoneal mast cells by arginine-rich and lysine-rich calf thymus histones was investigated. The arginine-rich histone released the esterase, but the lysine-rich histone did not release the esterase from the mast cells. The isolated mast cells spontaneously released the esterase gradually. The chymotrypsin-like esterase released from the mast cells is considered to digest the destructed material in tissues in a state of chronic destruction, such as chronically inflamed tissues and malignant tumours.

Animals↗