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Biomedical subjects

T Yagihara

Publications and source records attributed to T Yagihara.

At least 163 records · Page 9Linked to original sources
PubMed1981

Corrective surgery for tetralogy of Fallot without or with minimal right ventriculotomy and with repair of the pulmonary valve.

Thirty-six of 42 consecutive patients who underwent corrective surgery for tetralogy of Fallot were operated upon without or with minimum right ventriculotomy and with repair of the pulmonary valve. The other six patients underwent conventional right ventriculotomy primarily because they required external valved conduits for repair. One of the 36 patients (2.8%) died 11 days postoperatively. Postoperative hemodynamic and angiocardiographic studies were performed randomly in eight patients. The results were compared with those obtained from 21 control patients who underwent conventional corrective surgery with right ventriculotomy and without repair of pulmonary valve. There were no differences in the degree of residual pulmonary stenosis. Moderate-to-severe pulmonary regurgitation occurred in none of the patients who underwent the new procedures and in 24% of the controls. Cardiac and stroke volume indexes at rest measured postoperatively did not differ significantly between the two series of patients. The cardiac index for both series of patients increased significantly during isoproterenol infusion, measuring 7.29 +/- 1.97 l/min/m2 for the present series of patients (p less than 0.005) and 5.76 +/- 1.64 l/min/m2 for the controls (p less than 0.001). These two values were significntly different (p less than 0.05). Stroke volume index in the present series of patients increased significantly during isoproterenol infusions., from 37 +/- 5 ml/m2 to 45 +/- 15 ml/m2 (p less than 0.05), whereas that for the controls decreased significantly, from 43 +/- 10 ml/m2 to 38 +/- 12 ml/m2 (p less than 0.01). These differences in the response to isoproterenol infusion in the two series of patients indicated that right ventricular function after corrective surgery for tetralogy of Fallot was well maintained in patients who underwent the new method of operation. The two series of patients did not differ with respect to the development of right bundle branch block.

Adolescent↗
PubMed1981

[Determination of right ventricular volume by subxiphoid two-dimensional echocardiography (author's transl)].

To establish the measurement method of right ventricular (RV) volume by two-dimensional (2-D) echocardiography, a comparative study was performed in respect to the quantitative evaluations of the RV areas or volumes obtained by biplane 2-D echographic and angiographic methods. At first, a preliminary investigation was performed to define the optimum tracing of the endocardial surface on the 2-D echogram by using a fresh mongrel dog heart. It was revealed that the 2-D echographic views of the ventricular surface contained some artifact echoes inside the true echo of the endocardium. As a result, the optimum line for tracing was considered to be in external margin of the echo which seemed to represent the endocardium. This technique was then applied to 10 patients with congenital heart disease who were followed by cardiac catheterization. Ages ranged from 9 months to 5 years with an average of 2 years and 4 months. The RV was imaged by a subxiphoid approach. The RV apex, pulmonary valve (PV) and mid-portion of the tricuspid valve were showed in a frontal view, which allowed to measure the frontal RV area (f). In a sagittal plane, the RV wall and the PV were imaged, and then the lateral area (l) and the RV long axis (d) were measured. From the biplane cineangiography, the frontal RV area (f') lateral area (l'), RV long axis (d') and RV end-diastolic volume (EDV) by arealength method were calculated. The f and l were correlated with the f' (r = 0.90) and with the l' (r = 0.86), respectively. However, the values by the echocardiographic measurement were smaller than those by the cineangiographic ones. The f was also well correlated with the RVEDV (r = 0.94). The f.l/d, considered to represent a variable of echography measurement of the RV volume by area-length method, was well correlated with the RVEDV (r = 0.84). Although there are still some problems related to the imaging technique and sharpness of the echogram, further improvement to establish a echocardiographic measurement of RV volume is expected with the advance of the techniques.

Animals↗