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Biomedical subjects

T Wronski

Publications and source records attributed to T Wronski.

6 recordsLinked to original sources

The volume elasticity of the heart: a method for its evaluation under closed chest conditions.

A method is described for measuring the volume elasticity of the heart under closed chest conditions by simply inserting a catheter in the left ventricle. The heart as a system capable of oscillations detunes an external oscillating system. The shift in resonance frequency is a measure of the volume elasticity. The time course of diastolic volume elasticity values during one filling phase shows that active mechanisms are involved in the filling. The method can be applied to human beings: it allows the measurement of the volume elasticity of the whole ventricle and of small areas of the myocardium.

Blood Pressure

The influence of mixed venous pO2 on the natriuretic activity of cat plasma.

Plasma was taken from anaesthetised cats with high or low mixed venous pO2. Different plasma fractions were then administered to anaesthetised rats to examine the effect on sodium excretion. It was found that only the low molecular weight fraction of the plasma from cast with high mixed venous pO2 showed any natriuretic activity. A lipid soluble extract from the same plasma also increased sodium excretion. It is concluded that an increase in mixed venous pO2 in anaesthetised cats leads to the release or activation of a natriuretic factor, which has a molecular weight below 700 and is lipid soluble.

Animals

Premedical and medical school performance in predicting first-year residency performance.

In the study reported here the authors examined the relationships among 40 measures of undergraduate college and medical school performance and competence in 18 medical care tasks during the first year of residency. A rating form was developed for the study to assess residents' competency in the medical care tasks and was sent to the directors of the residency programs entered by the graduates of a medical school. Stepwise multiple regression procedures were used to analyze the relationship between these ratings of residency performance and the residents' premedical and medical school performance and to identify the best predictors of residency performance for the 1982 and 1984 classes. A Rasch model analysis of the residency performance ratings indicated the ease or difficulty of each of the 18 tasks. The results provide information that would allow medical educators to use premedical and medical school performance to predict residents' competencies. The task of "clinically evaluates research and clinical data" was the most difficult for the graduates; that is, they were rated lower on it than on any other task. Two groups of measures of undergraduate and medical school performance were significantly related to performance in the residency: the Part II examination of the National Board of Medical Examiners (particularly the scores on the obstetrics-gynecology, medicine, surgery, and pediatrics subtests and the overall score) and the clerkships (particularly the third-year medicine clerkship, the fourth-year medicine clerkship, and the surgery clerkship).

Chicago