As a result of our preliminary study which confirmed the safety and promising clinical usefulness of 67Ga-DFO-DAS-fibrinogen, scintigrams were taken on seven patients with suspected thrombosis. No evidence of radioactivity accumulation was found in the sites of suspected thrombi. However, in one patient accumulation of 67Ga-fibrinogen was observed in thrombi localized in the obstructed internal shunt for hemodialysis. A photon-deficient area corresponding to a gigantic thrombus in the left atrium was seen in an early 67Ga-fibrinogen image in a patient with mitral stenosis. Accumulation of radioactivity in the atrial thrombus was not observed in a later image. The necessity of performing 67Ga-fibrinogen scintigraphy in the acute phase of thrombus formation is discussed. The promising usefulness of 67Ga-fibrinogen for the early detection of thrombus formation in internal shunts for hemodialysis is also emphasized.

Adult↗

PubMedDate not supplied

Medical electronics in surgery.

I have described the results of a telemetering radio capsule which we used in the clinical assessment of digestive disease. This method has many merits which we have never found with other methods. This is one example of the clinical use of medical electronics. Medical electronics provides surgeons with many useful aids to improve diagnosis and treatment of their patients. Medical electronic technics should be used more often.

Female↗