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Biomedical subjects

T Washizu

Publications and source records attributed to T Washizu.

At least 55 records · Page 3Linked to original sources
PubMed1990

Altered mitogen response of peripheral blood lymphocytes in different stages of feline immunodeficiency virus infection.

To elucidate relationship between disease progress and immunologic alteration in feline immunodeficiency virus (FIV) infection, we classified naturally infected cats into clinical stage groups using the working criteria modified from those for human immunodeficiency virus (HIV) infection. Among the five distinct stages described for HIV infection, the three phases; asymptomatic carrier (AC), AIDS related complex (ARC), and acquired immunodeficiency syndrome (AIDS), were evaluated for concanavalin A (Con A)-induced lymphocyte blastogenic activities by using glucose consumption assay. There was a significant decrease of lymphocyte response in AC phase. The loss of response became marked as the disease progressed to ARC and AIDS, with an almost complete loss of mitogen response in AIDS phase. In addition to the loss of a lymphocyte function, AIDS in FIV infection was characterized by marked emaciation, anemia or pancytopenia, and postmortem evidences of opportunistic infections and lymphoid depletion.

AIDS-Related Complex↗
PubMed1989

Feline immunodeficiency virus infection in cats of Japan.

A seroepidemiologic survey for feline immunodeficiency virus (FIV) infection was conducted in Japan. Between June and December 1987, individual sera (n = 3,323) were submitted by veterinary practitioners from many parts of the country. Specimens were from 1,739 cats with clinical signs suggestive of FIV infection and from 1,584 healthy-appearing cats seen by the same practitioners. The overall FIV infection rate among cats in Japan was 960/3,323 cats (28.9%). The infection rate was more than 3 times higher in the clinically ill cats, compared with that in the healthy cats of the same cohort (43.9 vs 12.4%). Male cats were 1.5 times as likely to be infected as were females. Almost all FIV-infected cats were domestic cats (as opposed to purebred cats). Complete clinical history was available for 700 of 960 FIV-infected cats. Of these 700 FIV-infected cats, 626 (89.4%) were clinically ill, and the remainder did not have clinical signs of disease. The mean age at the time of FIV diagnosis for the 700 cats was 5.2 years, with younger mean age for males (4.9 years) than for females (5.8 years). Most of the infected cats (94.7%) were either allowed to run outdoors or had lived outdoors before being brought into homes. The mortality for FIV-infected cats during the 6 months after diagnosis was 14.7%, and the mean age at the time of death was 5.7 years. Concurrent FeLV infection was seen in 12.4% of the FIV-infected cats, but this was not much different from the historical incidence of FeLV infection in similar groups of cats not infected with FIV.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗
PubMed1987

Atrial fibrillation in the cow, pig, dog, and cat.

Atrial fibrillation (AF) is the most frequently observed arrhythmia in milking cows. About 50% of AF-affected cows have a history of ketosis, suggesting a relationship between AF and ketosis. Clinical signs of AF include a sudden decrease in milk production and an unstable appetite. Oral administration of quinidine is effective in the treatment of AF. AF in the pig has been observed only in one breeding animal. The clinical signs included anorexia and abnormal heart sounds. The AF was successfully terminated by the administration of 10 mg/kg quinidine every 8 h. AF in dogs and cats appears as a sign of cardiac failure, although AF may also be observed in large dogs without any underlying cardiac disease. Direct current defibrillation is effective in the treatment of these animals.

Animals↗
PubMed1984

A study of sequential anastomoses in aortocoronary bypass surgery--internal configuration by the casting injection technique.

Presently, sequential aortocoronary bypass grafting is a widely used method for the revascularization of multiple coronary vessel disease. In this study, the internal configurations of the anastomosed portions were investigated by casting models and the following results were obtained: In crossed side-to-side anastomoses with longitudinal incisions, the anastomosed area for the incised length was larger than in the other anastomosis techniques. Interrupted sutures produced a larger anastomosed area for the incised length than other suture techniques. Crossed side-to-side anastomoses with one longitudinal and one transverse incision resulted in the most frequent reoccurrence of narrowings.

Animals↗